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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 111 - 120 of 207728 results
  1. Novel Bispecific Nanotherapeutics as Broad-Spectrum Influenza Antivirals Refractory to Viral Escape

    SBC: Eitr Biologics, Inc.            Topic: CDC

    Project Summary Influenza A viruses (IAVs) have caused four pandemics since the turn of the 20th century. The 1918-1919 “Spanish Flu” was the most severe and is estimated to have caused more than 50 million deaths worldwide. A rapid response in the face of the next pandemic depends on the availability of pre-positioned medical countermeasures, including vaccines and therapeutics. These medical ...

    SBIR Phase I 2023 Department of Health and Human ServicesCenters for Disease Control and Prevention
  2. Rapid Point-of-Care Detection of Human Papillomavirus

    SBC: ELECTRONUCLEICS INC            Topic: CDC

    Project Summary The goal of this project is to demonstrate feasibility of a rapid (≤5 mins), sensitive system for the point-of-care (POC) detection of human papillomavirus (HPV) in human vaginal samples that integrates our patented detector of pathogens based on identification of species-specific, nucleic acid (NA) sequences. The detector relies on a patented electromechanical signal transductio ...

    SBIR Phase I 2023 Department of Health and Human ServicesCenters for Disease Control and Prevention
  3. Development of a High Throughput Assay for Rapid Detection of HSV and Treponema pallidum

    SBC: Microgen LLC            Topic: CDC

    Project Summary In response to NOT-EB-21-001 (Small Business Initiatives for Innovative Diagnostic Technology for Improving Outcomes for Maternal Health), we propose to develop a high-throughput, user-friendly diagnostic test for Treponema pallidum (T. pallidum) and Herpes simplex virus (HSV types 1 and 2) at the point-of-care (POC). Microgen’s POC test is likely to reduce costs and turn-around ...

    SBIR Phase I 2023 Department of Health and Human ServicesCenters for Disease Control and Prevention
  4. Culture-free microbial enrichment for diagnosis and characterization of anti-microbial resistance

    SBC: Triangle Biotechnology, Inc.            Topic: CDC

    Abstract Timely identification of infectious agents enables targeted antibiotic administration and better health outcomes for patients. However, current methodologies take days to months, leading to the administration of broad- spectrum antibiotics when they may not be appropriate or effective. Drastic cost reductions of DNA sequencing technologies have led to increased demand for such workflows t ...

    SBIR Phase I 2023 Department of Health and Human ServicesCenters for Disease Control and Prevention
  5. RNA aptamers for rapid response to COVID-19 variants

    SBC: DOTQUANT LLC            Topic: CDC

    ABSTRACT The COVID-19 pandemic caused by SARS-CoV-2 viruses has had an unprecedented disruptive global impact. Although vaccination has been expected to end the spread, the fast mutations have increased the breakthrough infection rates in the fully vaccinated population. RNA viruses are known to have very high rates of mutation and evolution. The high rate of mutation is correlated with virulence ...

    SBIR Phase I 2023 Department of Health and Human ServicesCenters for Disease Control and Prevention
  6. Development of a rapid, direct from blood, phenotypic antimicrobial susceptibility assay

    SBC: Aincobio LLC            Topic: CDC

    PROJECT SUMMARY Early treatment with effective antibiotics significantly improves clinical outcomes associated with bloodstream infection. However, the phenotypic antimicrobial susceptibility tests (AST) required to choose the right antibiotics take 4-24 hours (often longer in practice) following a 24–48-hour culture, which significantly exceeds the window within which treatment must begin to av ...

    SBIR Phase I 2023 Department of Health and Human ServicesCenters for Disease Control and Prevention
  7. Microfluidic immunoassay as a polysubstance oral fluid screening tool for law enforcement to rapidly identify recent drug use in traffic stops to reduce traffic fatalities and injuries.

    SBC: PORTABLE DIAGNOSTIC SYSTEMS INC            Topic: CDC

    Abstract More Americans are driving under the influence of drugs (DUID) than ever before, leading to an increase in fatal motor vehicle accidents. With more than 12 million drivers DUID each year, only a fraction of law enforcement officers (8%) has the advanced training needed to recognize drug impairment in roadside traffic stops, representing about 220 drivers DUID for every patrol officer with ...

    SBIR Phase I 2023 Department of Health and Human ServicesCenters for Disease Control and Prevention
  8. Lateral Flow Assay to Detect Malaria

    SBC: ATTOGENE CORPORATION            Topic: CDC

    Summary/Abstract Malaria is a deadly disease transmitted by mosquito bites. Every year, many millions of people in developing areas are affected by this disease. Children under 5 are most vulnerable to malaria. Great strides have been made to develop vaccines and medicines to prevent and treat malaria. The number of annual malaria deaths has decreased by about 85% in the past 100 years. This said, ...

    SBIR Phase I 2023 Department of Health and Human ServicesCenters for Disease Control and Prevention
  9. Secure and Efficient Architecture and Protocol via Ledger based Algorithms on decentralized NEtworks (SEAPLANE)

    SBC: STOTTLER HENKE ASSOCIATES, INC            Topic: N232094

    Stottler Henke proposes Secure and Efficient Architecture and Protocol via Ledger based Algorithms on decentralized NEtworks (SEAPLANE). SEAPLANE is a certificate-based authentication system which makes use of a hierarchical certificate authentication model. A node will represent a platform and each node will have a CRYSTALS-Dilithium public-private key pair that will be used when signing and vali ...

    SBIR Phase I 2023 Department of DefenseNavy
  10. DHS DoD 13.2-A13-089-MaXentric Technologies LLC

    SBC: MAXENTRIC TECHNOLOGIES LLC            Topic: A13089

    DHS in support of FEMA identifies a need for a sensor system to detect potential survivors buried in rubble piles or confined spaces in the event of a building collapse. In response to the solicitation, MaXentric proposes a radar-based system capable of detecting motion through debris such as respiration and/or heart beats. The system will alert the user of a potential victim's location relative t ...

    SBIR Phase II 2023 Department of Homeland SecurityScience and Technology Directorate
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