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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Blockade of histamine-releasing factor as a new prophylactic and therapeutic strategy for food allergy

    SBC: ABWIZ BIO INC            Topic: NIAID

    DESCRIPTION provided by applicant The prevalence of food allergy has been dramatically increasing for the last few decades Food Allergy and Anaphylaxis Network www foodallergy org estimates that up to million Americans have food allergies Six to eight percent of children under the age of three have food allergies and nearly four percent of adults have them Signs and symptoms of food all ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. A NEW HOLOGRAPHIC 3D CAMERA FOR FUNDUS IMAGING

    SBC: CELLOPTIC            Topic: N

    A NEW HOLOGRAPHIC D CAMERA FOR FUNDUS IMAGING Abstract In the United States retinal disease is the most common cause of visual impairment with age related macular degeneration AMD and diabetic retinopathy DR being the most common retinal diseases For each of the above conditions high resolution and three dimensional D imaging of the retina retinal vasculature choroid and or retinal ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Software for Determining Proteoform Heterogeneity and Protein Expression Fidelity

    SBC: GENNEXT TECHNOLOGIES, INC.            Topic: 400

    The importance of large protein drugsbiopharmaceuticalsand their generic counterpartsknown as biosimilarshas created a need for improved analytics to facilitate biopharmaceutical research and to combat adverse drug reactionsThe recombinant protein expression process is inherently prone to low level errors resulting in sequence variants caused by amino acid misincorporationwhich are observed in bot ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Pre-clinical Development of a Vaccine for the Treatment of Heroin Addiction

    SBC: MOLECULAR EXPRESS, INC            Topic: R42

    DESCRIPTION provided by applicant Heroin and related opioids are highly addictive drugs known for their analgesic properties Since the number of heroin users in the United States has skyrocketed reaching epidemic levels Abuse of prescription opioid pain relievers oxycodone Oxycotin and hydrocodone Vicodin which are known gateway drugs to heroin has also increased dramatically Beca ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Utilization of cord blood-expanded stem cells for megakaryocyte and platelet production

    SBC: AllCells, LLC            Topic: NHLBI

    DESCRIPTION provided by applicant Platelet transfusions are the most effective treatments for patients with thrombocytopenia The growing demand for platelet transfusions is often limited by shortage in the platelets PTL supply due to dependency on volunteer donors short shelf life risk of infections and alloimmunization It is therefore critical to create an efficient donor independent ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  6. A Tool for Research on Emotion in Naturally Occurring Speech

    SBC: Converspeech LLC            Topic: NLM

    DESCRIPTION provided by applicant A Tool for Research on Emotion in Naturally Occurring Speech It is now widely accepted that defects or limitations in emotion processing underlie many disorders such as anxiety depression bipolar and eating disorders If bio behavioral markers of emotions could be found researchers would have the basis for investigating emotions in both normal mental functi ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Effectiveness of VBP15, a dissociative steroidal analogue, on inflammation in a mouse model of arthritis

    SBC: REVERAGEN BIOPHARMA, INC.            Topic: NIAMS

    DESCRIPTION provided by applicant Glucocorticoids GCandapos s such as prednisolone are used frequently to induce remission and treat rheumatoid arthritis RA Despite effectiveness many GC mediated detrimental side effects including osteoporosis and muscle atrophy limit long term chronic treatment of RA patients In addition juvenile arthritis patients suffer from th side effect of signi ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Developing a novel adjuvant system for therapeutic vaccines against lung cancer

    SBC: FasCure Therapeutics LLC            Topic: 102

    DESCRIPTION provided by applicant Therapeutics is focused on the development of adjuvant systems with desired immune activities for targeted indications The Companyandapos s immune stimulatory adjuvant platform builds on combinatorial use of immune agonists with distinct immune targets and mechanisms of action for the generation of therapeutic immune responses Critical to this platform techno ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. An Agent-Based Modeling Platform for Environmental Biotechnology

    SBC: MICROVI BIOTECH, INC.            Topic: NIEHS

    DESCRIPTION provided by applicant Hazardous compounds in waters and soils are subject to a complex dynamic web of interactions among physical chemical and biological constituents in the natural environment Computational modeling has been proven indispensable to hazardous substances remediation particularly integrated modeling of pollutant hydrogeological fate and transport For the first t ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Novel noninvasive diagnostic technology for dynamic imaging of mitochondrial bioenergetics in breast cancer patients

    SBC: ROBIN MEDICAL INC            Topic: 102

    Summary Breast cancer is the second most common and the major cause of cancer related death of women in the USA The last decade has witnessed major advancement of therapeutic drugs and tools while noninvasive diagnostic imaging tools to measure interventions received much less attention Currently the mainstay of noninvasive imaging in breast cancer relies primarily on anatomic imaging Metabol ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
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