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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Mitochondrial dysfunction in HAART: Point of care tests

    SBC: MITOSCIENCE, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): HAART is an effective treatment for HIV infection but can cause serious metabolic complications including lacticacidemia, lipodystrophy, peripheral neuropathies, and cardiomyopathies. There is considerable evidence that the metabolic complications are the result of unintended mitochondrial toxicity of HAART. Because these complications can limit treatment, ther ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  2. Rapid Diagnosis of Monkeypox and Smallpox Infections

    SBC: NAJIT TECHNOLOGIES INC            Topic: N/A

    DESCRIPTION (provided by applicant): Smallpox and monkeypox represent two dangerous orthopoxviruses that can cause high morbidity and mortality - as well as widespread fear in unvaccinated populations. Although the last case of natural smallpox infection occurred in 1977, it was weaponized by the former Soviet Union and remains a significant concern due to the potential that stocks of this highly ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  3. Chitosan hemostatic device for laparoscopic applications

    SBC: HemCon Medical Technologies Inc            Topic: N/A

    DESCRIPTION (provided by applicant): Intraoperative bleeding can be a serious problem in parenchymal organ surgery and is generally difficult to manage during laparoscopic procedures. Our long-term goal is to develop a novel internal chitosan hemostatic device that can be deployed laparoscopically to control severe bleeding. External chitosan based hemostatic dressings have been applied success ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  4. Internet-based Fidelity Enhancement of MTFC

    SBC: Tfc Consultants, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The fields of mental health, child welfare, and juvenile justice are jointly faced with the challenge of reducing the prevalence of antisocial behavior among adolescents. In the last 20 years, conduct disorders have moved from being considered intractable difficulties to having difficult but available solutions. Empirically-validated interventions are now being ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  5. Osteopontin, a Novel Neuroprotectant in Brain Ischemia

    SBC: VIROGENOMICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This is an STTR Phase II proposal to develop the application of a novel neuroprotectant in the treatment of stroke. As in our previous Phase I STTR, this Phase II STTR unites the Stenzel-Poore laboratory and Virogenomics, Inc., a Portland-based genomics and drug discovery company. Here we plan to develop the use of an endogenous 'injury response' protein, osteo ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  6. HLA-DR4-derived RTLs for Treating Rheumatoid Arthritis

    SBC: VIROGENOMICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The specific goal of this Phase I STTR is to design, manufacture, characterize and evaluate a set of therapeutic agents that can control the pathogenic CD4+ T cells that mediate an inflammatory autoimmune disease, rheumatoid arthritis (RA). The approach presented is based on patented Recombinant T cell receptor Ligand (RTL) technology (US Patent # 6,270,772) fo ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
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