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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A web-based platform to support team-based genome diagnostics

    SBC: FRAMESHIFT LABS INC            Topic: 172

    Summary/Abstract Genomic sequencing is rapidly becoming a standard tool in diagnosing complex diagnostic cases, especially in critically ill newborns, and patients suffering from rare diseases. Current programs focused on addressing these cases utilise a team-based approach to identify, interpret and evaluate a patient’s genetic variants. These diverse teams include bioinformaticians, medical ge ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  2. The First Non-Surgical Anti-Stomal Prolapse Medical Device to Treat and Prevent Stomal Prolapse

    SBC: PEDIATRIC MEDICAL DEVICE COMPANY, LLC            Topic: 300

    ABSTRACT Intestinal stomas such as ileostomies and colostomies are openings of the intestinal tract surgically exteriorized onto the abdominal surface to divert enteric content away from distal cancer, obstruction, inflammation, and infection 5. In the US alone, about 1.5 million people have stomas14. Prolapse, or protrusion, of the bowel through the stoma is a common complication that can cause p ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  3. System for documenting and tracking skin lesions

    SBC: Lumo Imaging LLC            Topic: NIBIB

    Project Summary The objective of this STTR proposal is to develop a system for longitudinally tracking the locations and morphologic changes to all Pigmented Skin Lesions on the patient’s body. The proposed software will build on a previously developed Total Body Photography (TBP) system, called Lumo Scanner, that can provide unprecedented resolution across the entire body surface. Skin cancers, ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  4. Translating an In-Person Brief, Bystander Bullying Intervention (STAC) to a Technology-Based- Phase II

    SBC: KLEIN BUENDEL, INC.            Topic: 102

    While studies support the efficacy of comprehensive, school-wide interventions in reducing bullying, these types of programs can require significant time and financial resources for implementation, resulting in barriers to providing school-based bullying prevention, especially in low-income and rural communities. Additionally, although training bystanders to act as “defenders” on behalf of tar ...

    STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  5. Development of protease activity-based detector substrates for diagnosing Candida infections

    SBC: BIOSYNESIS, INC.            Topic: NIAID

    Project Summary/Abstract Members of the Candida genus of fungi form part of the normal human microbiota but are also opportunistic pathogens capable of causing serious mucosal and systemic infections. Candida cells grow and divide in suspension (planktonic) cultures, but they also form resilient and drug resistant biofilms – organized, tightly- packed communities of cells that attach to surfaces ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  6. Development of novel, targeted small molecule inhibitors of DNA repair in high unmet need tumors-TNBC

    SBC: DNATWO, Inc.            Topic: NCI

    DNATWO, Inc. was founded out of Caltech to develop small molecule drugs targeting a new cancer target, DNA2, to treat triple-negative breast cancer (TNBC). We have spent decades unraveling the role of the DNA2 ATP-motor driven nuclease activity in relieving replication stress at the replication fork and carrying out repair at forks collapsed to double strand breaks (DSBs). Our scientific premise i ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  7. An automated system to differentiate Kawasaki disease from febrile illness with real life clinical datasets in New York City

    SBC: HBI SOLUTIONS INC.            Topic: 100

    ABSTRACT – Kawasaki disease (KD) is the most common cause of acquired heart disease in children. Treatment with intravenous immunoglobulin (IVIG) reduces the incidence of coronary aneurysms and risk of long-term cardiovascular complications. IVIG is recommended to be given within 10 days of illness; however only 4.7% receive the correct diagnosis at the first medical visit. Timely and accurately ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  8. Clinical Decision Support System to Optimize Neonatal Nutrition and Growth

    SBC: Medical Predictive Science Corporation            Topic: NICHD

    Project Summary/Abstract: Clinical Decision Support System to Optimize Neonatal Nutrition and Growth Nutrition, defined as energy, macronutrients (protein, fat, and carbohydrates), and micronutrients (e.g., electrolytes), is a critical feature of care for preterm infants in the neonatal intensive unit (NICU). Inadequate nutrition is associated with growth and neurodevelopmental impairment, and inc ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  9. Development and Evaluation of an Integrated Biomarker Capture System for Use in Remote Trials

    SBC: MOUNTAINPASS TECHNOLOGY LLC            Topic: NCATS

    ABSTRACT Remote trials are led and coordinated by a local investigative team, but are based remotely, typically in the participant’s home. Remote trials offer several advantages over traditional in-person trials including: 1) a wider participant pool, 2) reduced regulatory hurdles, and 3) reduced participant burden. Remote trials face one key methodological limitation: the need for biomarker col ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  10. Glycoengineering of CHO cells to express recombinant alpha-1 antitrypsin

    SBC: NEUIMMUNE BIOLOGICS, INC.            Topic: NHLBI

    ABSTRACTAlpha-1 antitrypsin (A1AT) is well-established as a biotherapeutic used for the treatment of alpha-1 antitrypsin deficiency, and shows promise for treating a variety of other diseases. However, A1AT augmentation therapy carries unnecessary risk since it relies upon the weekly transfusion of plasma-derived product, which presents supply chain and contaminant risks. This could be remedied wi ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
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