Award Data

As the Web has become an increasingly important communication network, it has also become a resource for terrorists, criminals, insurgents and other adversaries. For this reason, military and intelligence analysts are increasingly interested in technology for monitoring and analyzing information on Web sites, social media and other sources.However, there are many difficult technical challenges inv ...

The modern warfighter faces the constant threat of endemic infections, multi-drug resistant bacteria and Biological Warfare Agents. In order to provide accurate front-line treatment that will curtail the overuse of antibiotics, a rapid and robust molecula

The Global Positioning System (GPS) and other Global Navigation Satellite Systems (GNSS) have created a single point of failure for many military applications requiring precise time and position. The Long Range Navigation (LORAN) system was a proven navigation aid until it was abandoned because of the success of GPS. Now it is clear that a backup to GPS is required and the enhanced-LORAN (eLORAN) ...

To address the SOCOM need for an innovative alternate means or a redundant positioning and navigation system for aircraft to operate in GPS-denied areas, Physical Optics Corporation (POC) proposes to develop a new Redundant Gimbal-less Navigation and Positioning (REGINA) system, providing precise all-weather, all-altitude, day/night navigation and positioning of aircraft. This proposed system is b ...

In this proposal, we aim to validate the human gut microbiome and arid soil as a source of antibiotic natural products (NPs ) by using ametagenomic NP discovery platform developed at Radiant Genomics. Recent studies suggest that the genomes of uncultivated microorganisms,like their cultivated counterparts, encode an enormous number of NPs. Gaining systematic access to NPs using standard, cultivati ...

Chemical and biological (CB) warfare agents are a serious threat to our soldiers and national security. Different warfare agents and microbes may be delivered using solids (powders, particulates, ice crystals), hydrosols (air borne liquid droplets), or aerosols (air-born particulates). Solids, hydrosols, or aerosols can penetrate, accumulate, and transport through both porous and non-porous surfac ...

Environmental DNA from three extreme samples will be isolated, cloned into a fosmid library (5760 clones) for sequencing. The sequencing datawill cover ~ 240 Megabases and will be assembled into contigs long enough (~ 40 Kilobases) to represent potential biosynthetic gene clusters(BGCs). This data will be compared to BGC databases looking for homology to antibiotic targets of DoD interest and with ...

Typical procedures for respirator masks sizing and protective fit test are time-consuming and user intensive, requiring taking anthropometric measurements of the wearer, sampling the wearers breathing zone and the use of specialized tools and equipment. The proposed software app aims to quickly, accurately and automatically perform respirator mask sizing and predict protective fit using only 2D im ...

To address USSOCOMs need for an environmentally stable, rapid, portable comprehensive blood analyzer system, Physical Optics Corporation (POC) proposes to develop a new Integrated Paper-Based Microfluidic Blood Analyzer for use in Austere Environments (iBLAdE) based on electrochemical measurements of different panels of electrolytes, metabolites, blood gases, and blood typing antigens within a mic ...

To address CBDs need for development of analytical approaches to fuse sensor data from multiple modalities to provide common operationalpictures in threat environments, Physical Optics Corporation (POC) proposes to develop a Wavelet-based Approach for Signal Processing andAnalysis (WASP). WASP is based on novel application of wavelet-based analysis to multimodel, multidimensional data available fr ...