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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Erbb2 Targeted Novel Microbial Anticancer Agents

    SBC: BIOMES, INC.            Topic: N/A

    The long-term objective of this research is the discovery of novel cancer chemotherapeutic naturalsought target of action of these agents is the erb32 proto-oncogene and its protein products. The soproducts will be a current culture collection of deep sub- terrestrial oligotrophic micro-organisms.suggests erbB2 may be a selective tumor target. Current work demonstrates that the deep subsurface hno ...

    SBIR Phase I 1995 Department of Health and Human Services
  2. Carbon 13 Lipids, Oral Absorption in Cystic Fibrosis

    SBC: Biomolecular Products, Inc.            Topic: N/A

    Cystic fibrosis (CF) is a lethal disease with a median survival age of 29 years in 1991. Increasedsurvival is associated with a more normal growth curve. However, growth failure continues to be aproblem; for example, approximately 40% of the CF individuals in 1990 were below the 5th percentilefor normal weight and height. The nutritional deficit in CF is associated with pancreatic insufficiencyand ...

    SBIR Phase I 1994 Department of Health and Human Services
  3. PURIFICATION SYSTEM FOR HYPOTHALAMIC INHIBITORY FACTOR

    SBC: Bion, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1996 Department of Health and Human Services
  4. Early Diagnosis of Mucosal Cancer by Confocal Scanning

    SBC: MEDISPECTRA, INC.            Topic: N/A

    Tumors originating in the mucosa account for more than half of all cancer deaths in the US;therefore, early detection is important. We will apply a novel technique to real-time diagnosis andassessment of precancerous growth and early cancer of the mucosa, by measuring its fluorescenceindependently of the much stronger submucosal fluorescence. Fluorescence and scatteringmeasurements of the lining o ...

    SBIR Phase I 1994 Department of Health and Human Services
  5. Cervical Cancer Diagnosis by Volume Probe Telemicroscopy

    SBC: MEDISPECTRA, INC.            Topic: N/A

    In the US, incidence of cervical cancer in young whites is increasing and at the present rate willapproximately 20 years, although Pap smear screening has intensified. Incidence in whites and minoriequality; in developing countries, cervical cancer is the most frequent cause of disease and death fthe US, women with atypical smears are evaluated by colposcopic examination and, usually, tissue bioex ...

    SBIR Phase I 1995 Department of Health and Human Services
  6. Multidose Dispenser for Unpreserved Ophthalmic Solutions

    SBC: BIOPOLYMERIX, INC.            Topic: N/A

    N/A

    SBIR Phase I 1994 Department of Health and Human Services
  7. HEMOPURE PROTECTION AGAINST ISCHEMIA/REPERFUSION INJURY

    SBC: BIOPURE CORPORATION            Topic: N/A

    N/A

    SBIR Phase I 1997 Department of Health and Human Services
  8. HIGHLY PURIFIED AND STABLE THERAPEUTIC BOTULINUM TOXIN

    SBC: BIOPURE CORPORATION            Topic: N/A

    N/A

    SBIR Phase I 1996 Department of Health and Human Services
  9. Hydroformed Microspheres as New Injectable Drug Vehicle

    SBC: BIOTEK, INC.            Topic: N/A

    We have developed a new hydroforming process for making sustained release injectablebiodegradable microsphere and microcapsule well suited for delivery of water soluble drugs such aspeptides and proteins. The process incorporates drug into hydroformed microspheres made of sparinglysoluble calcium minerals, such s calcium sulfate, which can then be overcoated with a polymer, mineralor lipid shell. ...

    SBIR Phase I 1994 Department of Health and Human Services
  10. Buprenorphine For Transdermal Analgesia

    SBC: BIOTEK, INC.            Topic: N/A

    We will demonstrate the practical feasibility of transdermal analgesic therapy based onbuprenorphine, a potent opioid already used intravenously and intramuscularly for the relief of moderateto severe pain. Preliminary in vitro experiments have confirmed that buprenorphine can pass throughhuman skin at potentially therapeutic rates. Using BIOTEK's patented DermaPatch transdermal systemit should be ...

    SBIR Phase I 1994 Department of Health and Human Services
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