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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. MODIFIED SURFACES FOR CHEMICALLY DEFINED CELL CULTURE

    SBC: Tekmat Corp            Topic: N/A

    THE PRIMARY GOAL OF THIS RESEARCH IS IN THE DEVELOPMENT OF NOVEL PLASTICS ON WHICH TO CULTURE CELLS IN SERUM-FREE MEDIA. CURRENTLY, BIOLOGICAL ATTACHMENT AIDS MUST BE USED FOR ANCHORAGE-DEPENDENT CELLS TO ATTACH AND GROW NORMALLY INTHE ABSENCE OF SERUM. WE WILL EMPLOY LOW TEMPERATURE GAS PLASMA TECHNIQUES TO MODIFY THE SURFACES OF POLYSTYRENE CULTUREWARE. SUCCESS WILL BE DETERMINED BY THE ABILITY ...

    SBIR Phase I 1991 Department of Health and Human Services
  2. PREPARATION OF NON-INFECTIOUS HIV-LIKE PARTICLES

    SBC: Therion Biologics Corp.            Topic: N/A

    N/A

    SBIR Phase I 1991 Department of Health and Human Services
  3. TELESIGN\VIDEO TELECOMMUNICATION OF SIGN LANGUAGE

    SBC: Topologic Systems Corpon            Topic: N/A

    THE PROJECT IS INTENDED TO SUPPLY LOW COST VISUAL COMMUNICATION MEANS FOR THE TRANSMISSION OF SIGN LANGUAGE OVER THE TELEPHONE SYSTEM. THIS WILL BE ACCOMPLISHED BY CONSTRUCTING A SYSTEM FOR REAL-TIME TWO-WAY VISUAL TRANSMISSION OF UPPER BODY OR FULL-HEAD IMAGE SEQUENCES, FOR SIGN LANGUAGE AND LIP READING, RESPECTIVELY, WITH PARAMETERS ADAPTED TO THE ISDN NETWORK OR THE SUBSCRIBER TELEPHONE NETWORK ...

    SBIR Phase I 1991 Department of Health and Human Services
  4. NOVEL ENZYME IMMOBILIZATION FOR BIOSENSOR APPLICATIONS (BACTERIA)

    SBC: Vertex Pharmaceuticals Inc.            Topic: N/A

    ENZYME CRYSTALS, CROSS-LINKED USING A BIFUNCTIONAL REAGENT SUCH AS GLUTARALDEHYDE, CONSTITUTE A NOVEL FORM OF ENZYME IMMOBILIZATION. SUCH CROSS-LINKED IMMOBILIZED ENZYME CRYSTALS (CLIECS) ARE SUPERIOR TO CONVEN- TIONALLY IMMOBILIZED ENZYMES IN MANY RESPECTS. FOR EXAMPLE, THE CRYSTAL LATTICE INTERACTIONS, SUPPLEMENTED BY CHEMICAL CROSS-LINKS, PROVIDE THE INDIVIDUAL ENZYME MOLECULES WITHIN A CLIEC W ...

    SBIR Phase I 1991 Department of Health and Human Services
  5. INVESTIGATION OF SAFER TEST TUBES FOR LABORATORY USE

    SBC: Virafree Corp.            Topic: N/A

    N/A

    SBIR Phase I 1991 Department of Health and Human Services
  6. ROTATIONAL ANGIOGRAPHIC DIGITAL IMAGING

    SBC: Xre Corp.            Topic: N/A

    N/A

    SBIR Phase I 1991 Department of Health and Human Services
  7. Heart Rate Variability Analysis Using Polynomial Network

    SBC: ABTECH CORPORATION            Topic: N/A

    High-risk newborn infants in an intensive care unit often suffer significant morbidity and mortalitybecause of infectious illnesses which elude early diagnosis and are present in advanced stages withcirculatory shock. Earlier diagnosis and therapy might present in advanced stages with circulatoryshock. Earlier diagnosis and therapy might prevent or reduce late complications and deaths. A strategyf ...

    SBIR Phase I 1994 Department of Health and Human Services
  8. Maclab Hypercard Tutorials for Physiology Teaching

    SBC: Adinstruments            Topic: N/A

    The initial step to producing a series of interactive HyperCard packages for laboratory instructionwill involve developing a template program based on the Physiology of striated muscle. The flexibilityinherent within the software programs will permit students to learn at their own level. QuickTime videosequences will be developed to display the experiment on the computer screen together with dataa ...

    SBIR Phase I 1994 Department of Health and Human Services
  9. Surface Modification of Polymers for Artificial Corneas

    SBC: AST PRODUCTS, INC.            Topic: N/A

    Opacification of the normally transparent cornea is among the leading causes of blindnessworldwide. Often vision can be restored by corneal transplantation but the procedure requires theavailability of a) suitable human corneal donor tissue; and b) a sophisticated eye banking system. It isfurther limited by the potential to transmit diseases such as AIDS and hepatitis. A significant advancewould b ...

    SBIR Phase I 1994 Department of Health and Human Services
  10. Large Area Digital Imaging System for Mammography

    SBC: RADIATION MONITORING DEVICES, INC.            Topic: N/A

    N/A

    SBIR Phase I 1994 Department of Health and Human Services
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