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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 1171 - 1180 of 8756 results
  1. Treatment of Restless Legs Syndrome through non-invasive peripheral nerve stimulation

    SBC: NOCTRIX HEALTH, INC.            Topic: NINDS

    Restless Legs Syndrome (RLS) affects the ability to fall and stay asleep for more than 10% of the western adult population. In the median age group of 50-79 years alone, more than 25 million adults are seeking treatment for RLS, making it the second most common sleep disorder in the world. The severe leg sensations of RLS are most prevalent at night, thus leading to sleep deprivation and its downs ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  2. DNA 3.0: Developing novel enzymes for DNA synthesis with deep learning and combinatorial genetics

    SBC: PRIMORDIAL GENETICS, INC.            Topic: NHGRI

    Project Summary/AbstractDNA synthesis has played a key role in the biotechnology revolution. The ready availability of synthetic DNA oligonucleotides and of genes assembled from them, has been invaluable for elucidating and unlocking biological function and enabling the new field of synthetic biology which can create novel cells, enzymes, therapeutics, diagnostics and other reagents of commercial ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  3. Submission of Investigational New Drug application to the Federal Drug Administration to support clinical development of topical pirenzepine for CIPN.

    SBC: WinSanTor, Inc.            Topic: NCI

    PROJECT SUMMARY Chemotherapy-induced peripheral neuropathy (CIPN) is a debilitating side effect of many first-line chemotherapeutic drugs. Depending on the specific drug and dose regimen, CIPN can afflict between 20-85% of cancer patients receiving these drugs at standard doses and nearly 100% of patients at high drug doses. Many patients with CIPN experience neuropathic pain, and there are no FDA ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  4. N6-Methyl-2'-O-Methyladenosine Sequencing

    SBC: ELECTRONIC BIOSCIENCES, INC.            Topic: 102

    Project Summary During this Phase I IMAT SBIR program, Electronic BioSciences, Inc. (EBS), specialists in nanopore platform/methodology developments and high-performance electronics integration, will demonstrate RNA adenosine methylation sequencing by directly differentiating the 3 most abundant adenosine methylations: N6- methyladenosine (m6A), N6,2’-O-dimethyladenosine (m6Am), and N1-methylade ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  5. Robust Visualization in CT Colonography

    SBC: KENTUCKY IMAGING TECHNOLOGIES LLC            Topic: 102

    Computed-Tomography Colonoscopy (CTC) refers to visualization of the colon surface (lumen) by radiologists following an abdominal CT scan of prepped patients. Removal of colonic polyps is performed by a minimally- invasive procedure known as Optical Colonoscopy (OC). Through a sequence of image analysis steps, a three- dimensional (3D) representation of the colon can be constructed, which is then ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  6. Speech Hero: a rhythm-based speech therapy app for individuals with aphasia

    SBC: FLINT REHABILITATION DEVICES, LLC            Topic: NIDCD

    It is estimated that 1 in 6 people worldwide will experience a stroke, with about 30% of those individuals experiencing aphasia, which is a loss in their ability to understand or express speech. Aphasia is associated with increased mortality, decreased rates of functional recovery and reduced probability to return to work compared with nonaphasic stroke patients. While intensive speech and languag ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  7. An Accurate, Non-invasive, and Cost-effective Methylome Test for Early Cancer Detection

    SBC: EARLYDIAGNOSTICS INC            Topic: 102

    The long-term goal of this project is to develop and market a commercially viable,blood-based methylation profiling test that can detect and locate cancer early. Clinicalintervention in the early stages of cancer can greatly improve the survival of cancerpatients. Despite the tremendous demand for early detection methods in the clinical practice, fewtechnologies exist on the market. To address thi ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  8. Low-Cost Instrument-free Point-of-Care Test for Chlamydia and Gonorrhea

    SBC: Lucira Health, Inc.            Topic: NIAID

    Summary Chlamydia trachomatis (Ct) and Neisseria gonorrhoeae (Ng) cause over 3 million sexually transmitted infections (STI) annually in the U.S. The estimated global rates are ~131 million and 78 million, respectively. These rates have been increasing 6% to 18% over the last few years. Both are responsible for severe morbidity, including pelvic inflammatory disease, infertility, ectopic pregnancy ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  9. Validating of Machine Learning-Based EEG Treatment Biomarkers in Depression

    SBC: ALTO NEUROSCIENCE, INC.            Topic: 102

    SUMMARY/ABSTRACT The overarching aim of Alto Neuroscience is to advance brain-based biomarkers for psychiatric disorders in order to both optimize treatment pathways and drive the development of novel pharmacological and non- pharmacological interventions. Alto does this by developing and applying sophisticated machine learning computational models to electroencephalography (EEG) data collected at ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  10. Rapid Low Cost Phenotypic Antibiotic Susceptibility Testing

    SBC: Specific Diagnostics, Inc.            Topic: NIAID

    Project Summary The rise and spread of antimicrobial-resistant (AMR) infection now makes it increasingly vital to speed the availability of phenotypic susceptibility test results. In the case of AMR organisms, the broad- spectrum antimicrobial therapy used to protect patients during the 2 day period required for growth of colonies and performance of overnight automated susceptibility testing (AST) ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
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