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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Ultraviolet-C Therapy for Onychomycosis

    SBC: KERADERM, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Keraderm LLC and the Wellman Center for Phototherapy propose a radically new treatment for onychomycosis using germicidal radiation instead of current medications which have significant drawbacks. Onychomycosis is a fungal nail infection that affects approximately 30 million Americans. Americans spend more than $1 Billion per year to treat this problem. However ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  2. REDUCING HEALTH CARE COSTS AND IMPROVING QUALITY OF CARE

    SBC: Oztech Systems, Inc.            Topic: N/A

    N/A

    STTR Phase I 1998 Department of Health and Human Services
  3. DEVELOPMENT OF AN ELECTROCHEMICAL GUSTOMETER

    SBC: Electrodermal Diagnostics            Topic: N/A

    N/A

    STTR Phase I 1998 Department of Health and Human Services
  4. FAST LIGAND FOR PROTECTION OF TRANSPLANTED B ISLET CELLS

    SBC: Chrysallis Research Laboratori            Topic: N/A

    N/A

    STTR Phase I 1998 Department of Health and Human Services
  5. CANCER THERAPY THROUGH REDIRECTING NATURAL ANTIBODIES

    SBC: SANGSTAT MEDICAL CORPORATION            Topic: N/A

    N/A

    STTR Phase I 1998 Department of Health and Human Services
  6. Reagents for Preparing Structure-Free DNA and RNA

    SBC: TRILINK BIOTECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Secondary structure in single-stranded ONA and RNA is a significant barrier to the efficient hybridization of short oligonucleotide probes. While some probes to a given target hybridize efficiently, other probes to the same target may not hybridize at all. Use of longer probes, on the order of 60 nucleotides in length, is one way to overcome this problem. Unfor ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  7. Dose Response/Dynamics Ultrasound Mediated BBB Opening

    SBC: Perfusion Technology, LLC.            Topic: N/A

    DESCRIPTION (provided by applicant): A wide range of brain disorders are inaccessible to therapeutic agents because of the blood-brain barrier (BBB). The BBB prevents most large molecule drugs and gene preparations from entering into brain tissue. A method to safely and reversibly change the permeability of the BBB is therefore needed. Preliminary data show that ultrasound can be used to reversib ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  8. Feasibility of a Home-based Self-Management Program for Chronic Fatigue

    SBC: WARREN STRESS MANAGEMENT            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term objective of this application is to establish a commercially viable program of illness self- management in people with unexplained chronic fatigue (UCF) and chronic fatigue syndrome (CFS). A successful self-management product has the potential (1) to improve the generally poor outcomes for UCF and CFS patients, (2) to greatly expand the availa ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  9. Development of a peptide array synthesis system

    SBC: Boston Array Technologies, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of phase I and II of this proposal is to develop microarray-based methods for high throughput profiling of proteins. This will be done in two different ways, one based on arrays of 100s of thousands of distinct peptides on 1 cm2 chips that can be used to fingerprint proteins, the other based on thousands or tens of thousands of antibodies again ...

    STTR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  10. Modified HER-2 Tumor Antigens for Vaccination in Cancer

    SBC: L2 DIAGNOSTICS LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The proposed studies are aimed at developing a new tumor immunotherapy by using isoaspartyl-modified peptides to break immune tolerance to "self" tumor antigens on breast cancer cells. Most tumor antigens have been characterized as normal, non-mutated self-peptides, linking the concepts of autoimmunity with the development of tumor immunity. Previous studies de ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
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