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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point of Care Applications

    SBC: GENECAPTURE, INC.            Topic: CBD15C001

    The modern warfighter faces the constant threat of endemic infections, multi-drug resistant bacteria and Biological Warfare Agents. In order to provide accurate front-line treatment that will curtail the overuse of antibiotics, a rapid and robust molecula

    STTR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  2. Exploiting Microbiome and Synthetic Biology to Discover and Produce Naturally Occurring Antibiotics

    SBC: Radiant Genomics, Inc.            Topic: CBD152004

    In this proposal, we aim to validate the human gut microbiome and arid soil as a source of antibiotic natural products (NPs ) by using ametagenomic NP discovery platform developed at Radiant Genomics. Recent studies suggest that the genomes of uncultivated microorganisms,like their cultivated counterparts, encode an enormous number of NPs. Gaining systematic access to NPs using standard, cultivati ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  3. Durable Aerosol and Liquid Repellent coatings

    SBC: HYGRATEK LLC            Topic: CBD161002

    Chemical and biological (CB) warfare agents are a serious threat to our soldiers and national security. Different warfare agents and microbes may be delivered using solids (powders, particulates, ice crystals), hydrosols (air borne liquid droplets), or aerosols (air-born particulates). Solids, hydrosols, or aerosols can penetrate, accumulate, and transport through both porous and non-porous surfac ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  4. Producing Novel Biosynthetic Therapeutics from Extreme Microbiomes

    SBC: iXpressGenes, Inc.            Topic: CBD152004

    Environmental DNA from three extreme samples will be isolated, cloned into a fosmid library (5760 clones) for sequencing. The sequencing datawill cover ~ 240 Megabases and will be assembled into contigs long enough (~ 40 Kilobases) to represent potential biosynthetic gene clusters(BGCs). This data will be compared to BGC databases looking for homology to antibiotic targets of DoD interest and with ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  5. Protective Mask Sizing App

    SBC: CFD RESEARCH CORPORATION            Topic: CBD161005

    Typical procedures for respirator masks sizing and protective fit test are time-consuming and user intensive, requiring taking anthropometric measurements of the wearer, sampling the wearers breathing zone and the use of specialized tools and equipment. The proposed software app aims to quickly, accurately and automatically perform respirator mask sizing and predict protective fit using only 2D im ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  6. Integrated Paper-Based Microfluidic Blood Analyzer for use in Austere Environments

    SBC: Physical Optics Corporation            Topic: SOCOM16002

    To address USSOCOMs need for an environmentally stable, rapid, portable comprehensive blood analyzer system, Physical Optics Corporation (POC) proposes to develop a new Integrated Paper-Based Microfluidic Blood Analyzer for use in Austere Environments (iBLAdE) based on electrochemical measurements of different panels of electrolytes, metabolites, blood gases, and blood typing antigens within a mic ...

    SBIR Phase I 2016 Department of DefenseSpecial Operations Command
  7. Wavelet-Based Approach for Signal Processing and Analysis

    SBC: Physical Optics Corporation            Topic: CBD152006

    To address CBDs need for development of analytical approaches to fuse sensor data from multiple modalities to provide common operationalpictures in threat environments, Physical Optics Corporation (POC) proposes to develop a Wavelet-based Approach for Signal Processing andAnalysis (WASP). WASP is based on novel application of wavelet-based analysis to multimodel, multidimensional data available fr ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  8. Signal Processing for Layered Sensing

    SBC: TOYON RESEARCH CORPORATION            Topic: CBD152006

    As a foundational component of a Layered Sensing architecture, Toyon proposes to develop a Multi-Modal Fusion Module (M2FM) capable ofconfirming detections from Chemical, Biological and Radiological (CBR) sensing networks by fusing together information from other (non-CBR)sensors. The module will provide information to assist operators in confirming an initial CBR detection or rejecting it as a fa ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  9. Mycotoxin Neutralization Treatment

    SBC: Physical Optics Corporation            Topic: CBD152003

    To address the Chemical and Biological Defense programs (CBDs) need for medical countermeasures against mycotoxin intoxication, PhysicalOptics Corporation (POC) proposes to develop a new Mycotoxin Neutralization Treatment (MyNT). This proposed solution is based on neutralizingmycotoxin from its deleterious effects by acting on multiple levels of mycotoxin metabolism through the novel combination o ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  10. Exploiting Natural Products-Based Therapeutics for Aflatoxin Mitigation

    SBC: CFD RESEARCH CORPORATION            Topic: CBD152003

    Aflatoxins are a paradigm among fungal produced mycotoxins that are present in food supplies and are strongly associated with increased risk forthe development of hepatocellular carcinoma. Currently, there are no known countermeasures that can selectively mitigate aflatoxin toxicity andthe available options are only symptomatic treatments. To meet this challenge, we propose to harness the microbio ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
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