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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.
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Culturally sensitive, evidence-based, Spanish language mobile app for smoking cessation for Latino cigarette smokersSBC: HEALTH BEHAVIOR SOLUTIONS INC Topic: 41
Cigarette smoking is the leading cause of mortality in the U Sresulting in overdeaths every year and costing more than $billion in loss of productivitySmoking is also the leading cause of cancer and of deaths from cancerAlthough the prevalence of smoking has declined over the pastyearslarge disparities in tobacco use remain across a number of groupsLatino a smokers represent a major health dispari ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: Sersense Inc Topic: NICHD
ABSTRACT Premature infants are frequently at risk of infectionjaundice and hypoglycemiaconditions monitored by analysis of blood for c reactive proteinCRPbilirubin and glucose respectivelyTypicallymL of blood is drawn each time an infant is tested with multiple blood draws happening over the course of daysGiven that total blood volume of in premature infants ismLup toof blood volume may be lost du ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: Navidea Biopharmaceuticals, Inc. Topic: NHLBI
Myocardial infarctionsMIor heart attacksischemic strokesISand peripheral artery diseasePADtogether considered cardiovascular diseaseCVDare all commonly caused by the same underlying pathologyatherosclerosisMIs and ISs are the leading causes of death and disability worldwideAtherosclerosis is a progressive pathology that develops asymptomatically over the course of many years as inflammatory plaque ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: Vova Ida, LLC Topic: 999
SUMMARYParkinsonandapos s diseasePDis the second most prevalent neurodegenerative disorder after Alzheimerandapos s diseaseADaffecting more thanmillion people in the United StatesBecause age is the major risk factorthe prevalence of both diseases is steadily increasing as our population agesPD belongs to the group of protein misfolding neurodegenerative diseases that are due to the misfolding and ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
The Daily Progress System- A Recovery Support Tool to Reduce Health Disparities in Outpatient Substance Use TreatmentSBC: COG ANALYTICS, LLC Topic: 102
ABSTRACTSubstance use disordersSUDsincluding opioid use disorderscontinue to be one of the most serious public health issues in the USleading to negative physical and mental health problemsfamily disruptionand premature deathAfrican Americans with drug use histories that are under criminal justice supervision are particularly vulnerable to experiencing the negative consequences associated with SUD ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
A dual histone deacetylase and glycogen synthase kinase 3 beta inhibitor for treating pancreatic adenocarcinomaSBC: Avenzoar Pharmaceuticals, Inc. Topic: 102
ABSTRACT Pancreatic cancer is a disease with no effective treatmentIt s low five year survival rateestimated at betweenandranks it the fourth highest of cancer related of death in the U Sdespite being the twelfth most common type of cancerEach year in the U Sthere are nearlynew cases and more thandeaths caused by the diseaseBypancreatic cancer is expected to be the second most common cancer relate ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: South Plains Biotechnology, Inc Topic: NIAMS
Our goal is to evaluate the efficacy of the FDA approved drug Carbidopa for the treatment of gouty arthritis in mouse modelsCarbidopa is used to treat Parkinson s diseasebut always in combination of L DOPAnever alone by itselfGouty arthritis is caused by deposition of monosodium urateMSUcrystals in jointsinitiating inflammation and arthritisInterestinglygout is not always directly related to incre ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: Microsurgical Innovations Inc Topic: 999
Project Summary Nerve injury can occur due to traumachronic compression or disease processes such as diabetes or tumors and have a tremendous socioeconomic impact from loss of work and healthcare costsThere is still a clinical need to improve recovery from nerve injuriesand a new nerve conduit drug delivery device that addresses this clinical need is the focus of the present proposalOur group has ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
Continuous real-time fentanyl sensor platform based on smart hydrogels for application in anesthesiaSBC: Sentiomed, Inc. Topic: 300
PROJECT SUMMARY ABSTRACT The opioid fentanyl is administered in millions of procedural sedations every yearIt is very potenthas large interpatient pharmacokinetic variabilityand routinely causes significant respiratory depression if bolused or not titrated judiciouslyDosing and timingcritical for safety and efficacyare presently only possible based on educated guesses and vital signsSedation assoc ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: Radiant Creative Group, LLC Topic: NICHD
ABSTRACT The goal of thisyear Fast Track STTR is to develop and evaluate a multi levelyouthparentschoolInternet based dating violenceDVprevention programMe andampYou TechMYTforthgrade middle school studentsByth gradeapproximatelyof students will have engaged in a dating relationshipOf thesealmost one third will have perpetrated physical DV and almost two thirds will have perpetrated emotional DVYo ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health