You are here

Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Implantable Recording and Integrated Stimulation (IRIS) device for cortical experiments

    SBC: RIPPLE LLC            Topic: 999

    Abstract We propose to build a hermetically sealed implantable stimulation and recording system to enable closed loop experiments while mitigating the need for percutaneous leadsThe IRISImplantable Recording with Integrated Stimulationis a fully implantable system capable of both stimulating and recording on large numbers of channelschannelsOur implantable technology will provide primate researche ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Development of TP-352 for the Treatment of Pediatric Non-alcoholic Steatohepatitis

    SBC: Thetis Pharmaceuticals LLC            Topic: 300

    ABSTRACTNon alcoholic fatty liver diseaseNAFLDrefers to a spectrum of diseases related to metabolic syndrome that are characterized by steatosisthe accumulation of fat within the liverNon alcoholic steatohepatitisNASHthe most aggressive NAFLD subtyperefers to the presence of inflammation and necrosis in a background of steatosisand is associated with hepatic fibrosisNASH is a serious health proble ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Stabilization of the Alveolar-Capillary Barrier with ARF6 Inhibitor as a Treatment for Severe Influenza

    SBC: NAVIGEN, INC.            Topic: NHLBI

    SUMMARYInfluenzavirusinfectionisoneofthemostcommonacuterespiratorydiseasesandremainsoneofthelargestdiseaseburdensonhumanswithsevereprimaryviralpneumoniaoftenresultingindeathThepathogenicityofinfluenzaincludesahostresponsethatcanincludeaseveresystemicinflammatoryreactioncytokinestormandensuingvascularleakVascularleakisafundamentalelementinthepathogenesisofcirculatoryshockandmultipleorganfailurewhic ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Photochemical Generation of Gas Phase Nitric Oxide from ImmobilizedS-Nitrosothiols for Biomedical Applications

    SBC: NOTA Laboratories, Inc.            Topic: NHLBI

    AbstractNitric oxideNOplays a critical role in a wide range of bodily functionsincluding vasodilationneurotransmissionwound healingsuppression of platelet activationand modulation of ciliary beat frequencyIn additionit is a potent and endogenous antimicrobial antiviral agent produced by macrophages and normally present at moderate levelsppmvwithin the upper airways sinuses of healthy individuals t ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Automatic Quantification and Labeling of Cerebral Microbleeds, Oxygen Saturation and Sources of Abnormal Susceptibility

    SBC: Magnetic Resonance Innovations, Inc.            Topic: NHLBI

    ABSTRACT The detectionlocalization and quantification of cerebral microbleedsCMBsplays an important role in diagnosing and establishing appropriate treatment plans in neurodegenerative diseases specifically in vascular dementiaVaDTo dateevaluating CMBs is time consuminginaccurate and sometimes not possibleWe propose to mitigate these problems by developing our softwareqSPINthat will provide fast a ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Improved Ratiometric Voltage-Sensitive Dyes for In-Vitro and In-Vivo Imaging of Brain Electrical Signaling

    SBC: POTENTIOMETRIC PROBES LLC            Topic: 101

    Project Summary/Abstract Potentiometric Probes Voltage-sensitive dyes can be applied to brain cells and tissue to study the electrical signals used by the brain to function. The fluorescent dye molecules light up under a microscope and convert tiny electrical signals to measurable changes in light intensity. Virtually all neurological disorders involve changes in the brain’s normal electrical ac ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Universal Membrane Dehydrator for Dewatering Pharmaceutical Solvents

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: 400

    Project Summary Specific AimThere are numerous needs in the pharmaceutical industry to use and recover high purity solventsKey uses includehigh purity alcohol for various applicationsthe ability to develop low cost dewatering of solvents and a relatively gentle and simple process for dewatering solvent under mild conditionsCompact Membrane SystemsCMSproposes a novel membrane process that can lead ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Development and Translation of novel SiC encapsulation thin film for chronic auditory nerve implant electrodes

    SBC: BLACKROCK MICROSYSTEMS, INC            Topic: NIDCD

    Abstract A range of neurological diseases are now being researched or treated using fully implantable electronic systems to either record or modulate brain activity in humansThese implants are currently being protected using polymer coatings that envelop the implant and help keep body fluids away from the sensitive electronicsBrain implants with complex three dimensional geometrieslike the Utah El ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Development of A Narrow Spectrum Anti-Tubercular Agent

    SBC: L2 DIAGNOSTICS LLC            Topic: NIAID

    Abstract Complex and lengthy treatment regimens coupled with rising drug resistance underscore the urgent need for new and better drugs to treat tuberculosis (TB) caused by the bacterium Mycobacterium tuberculosis (Mtb). Current treatment regimens for drug resistant TB involve the use of costly, less effective, and toxic drugs that must be continued for up to 24 months. The work proposed here focu ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Faster Optical Modem for Underwater Data Acquisition

    SBC: SONALYSTS INC            Topic: NGA182001

    To address NGA’s requirements, Sonalysts’ team of world-class experts in underwater optical communication proposes development and implementation of the Precision Optical Navigation Transceiver for Undersea Systems (PONTUS). PONTUS will transfer navigation information from an Underwater Navigation Beacon (UNB) to an Unmanned Undersea Vehicle (UUV) in an electromagnetic-spectrum-denied (e.g., G ...

    SBIR Phase I 2019 Department of DefenseNational Geospatial-Intelligence Agency
US Flag An Official Website of the United States Government