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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Development of Infection-Resistant Suture Materials

    SBC: BIOSURFACES INC            Topic: N/A

    DESCRIPTION (provided by applicant): Infection remains as one of the major complications associated with utilizing biomaterials. Surgical site infections account for approximately 14-16% of the 2.4-million nosocomial infections in the United States, with these infections resulting in increased patient morbidity and mortality. The inherent bulk properties of various biomaterials, including those ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  2. A Bioactive Prosthetic Vascular Graft

    SBC: BIOSURFACES INC            Topic: N/A

    DESCRIPTION (provided by applicant): Over 60,000 prosthetic grafts, which are comprised of either polyethylene terephthalate (polyester) or expanded polytetrafluoroethylene (ePTFE), are implanted in the United States each year. Medium (6-8mm) and small (l t5mm) internal diameter (I.D.) prosthetic arterial grafts continue to have unacceptably high failure rates when used in the clinical setting. T ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  3. A Nanofibrous Bioactive Prosthetic Sewing Cuff

    SBC: BIOSURFACES INC            Topic: N/A

    DESCRIPTION (provided by applicant): Cardiac valve replacement using prosthetic valves is indicated when progression of degenerative disease or bacterial infection of the native valve results in valvular dysfunction, thereby impacting on cardiac output. An estimated 50,000 prosthetic valves are implanted annually in the United States, with this number increasing due to an aging population and, to ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  4. Resuscitating Blood-Substituted Hypothermic Dogs

    SBC: BioTime, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Currently, due to high morbidity and mortality, the use of hypothermic circulatory arrest (HCA) is limited to only the most difficult surgical cases. During HCA, the body receives no perfusion, oxygen, or energy supply. Our goal is to develop technology to achieve hours rather than minutes of HCA during which extensive traumatic injuries and currently "unres ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  5. Development of Lysosomal Modulatory Drugs to Treat Alzheimer's Disease

    SBC: SYNAPTIC DYNAMICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Reducing protein deposition events is essential for slowing the progression of Alzheimer's disease (AD), especially A 1-42 peptide oligomers that accumulate inside and outside neurons and cause functional compromise. Finding a strategy to reduce A oligomeric assemblies is widely thought to be the key objective for treating AD. Accumulation of A peptides is on ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  6. Web-based Empowerment Program for Disaster Victims and First Responders

    SBC: BLUESUN, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This project will support research and further development of a novel commercializable product designed to reduce and mitigate the psychological impact of a major disaster. The long-term objective of this project is to provide a scientifically supported, highly accessible, culturally relevant, anonymous multi- media system that fills the current gap in mental ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  7. Development of a peptide array synthesis system

    SBC: Boston Array Technologies, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of phase I and II of this proposal is to develop microarray-based methods for high throughput profiling of proteins. This will be done in two different ways, one based on arrays of 100s of thousands of distinct peptides on 1 cm2 chips that can be used to fingerprint proteins, the other based on thousands or tens of thousands of antibodies again ...

    STTR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  8. Design of an Automated Psoriasis Treatment System

    SBC: Boston Array Technologies, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Up to 3 percent of populations worldwide have psoriasis. A large number of the patients with psoriasis can be treated using UV light exposure. We propose to employ a light modulating microchip based on recent Micro Electro Mechanical Systems (MEMS) technological developments to build an Automated Psoriasis Treatment System. The overall goal of Phase I a ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  9. N/A

    SBC: BOSTON MEDICAL PRODUCTS, INC.            Topic: N/A

    N/A

    STTR Phase I 2000 Department of Health and Human ServicesNational Institutes of Health
  10. DEVELOPMENT OF A MIDDLE EAR BALLOON IMPLANT

    SBC: BOSTON MEDICAL PRODUCTS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Development of a new type of middle ear implant, a "middle ear balloon" is proposed. This implant is intended to restore hearing in non-aerated ears by creating and permanently maintaining an air or gas-filled space within the middle ear. Non-aerated middle ears resulting from eustachian tube dysfunction camonly occur in chronic otitis media (COM) and in otitis ...

    STTR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
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