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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Molecular Diagnosis Kits for Beta Thalassemia

    SBC: AMERICAN LABORATORY SUPPLIES            Topic: N/A

    N/A

    SBIR Phase I 1994 Department of Health and Human Services
  2. Improved Isolation of Marine Natural Products

    SBC: APHIOS CORPORATION            Topic: N/A

    The overall goal of this R&D program is to develop improved methodologies and manufacturingprocesses for the isolation of marine natural products with anticancer or anti-HIV activity. Thetherapeutic potential of marine natural products has rapidly advanced in recent years. One suchpotential therapeutic is bryostatin I which is derived from the marine bryozoan Bugula neritana. Whileharvesting the b ...

    SBIR Phase I 1994 Department of Health and Human Services
  3. Fluorophore Labeled Nucleic Acid Probes

    SBC: APHIOS CORPORATION            Topic: N/A

    This investigation is aimed at devising ways and special instrumentation for using fluorescentlanthanide chelates, detected by time resolved fluorometry, as a means for detecting nucleic acids in avariety of settings such as Southern blots and cells or tissues (e.g., as in situ hybridization). Thesemethodologies have the potential of high sensitivity, since time-resolved fluorometry permits detect ...

    SBIR Phase I 1994 Department of Health and Human Services
  4. Supercritical Fluid Extraction of Michellamine B

    SBC: APHIOS CORPORATION            Topic: N/A

    N/A

    SBIR Phase I 1994 Department of Health and Human Services
  5. Software for Characterizing Laryngeal Dynamics

    SBC: Audiofile, Inc.            Topic: N/A

    Our company will create a software "tool" to characterize aspects of the structure andperformance of the larynx from analysis of speech. The analysis relies on the theory of nonlineardynamical systems, or "chaos theory". It provides parameters (Lyapunov exponents, metric entropy,attractor dimensions) which cannot be derived from conventional reduction but which have already beenshown to have value ...

    SBIR Phase I 1994 Department of Health and Human Services
  6. Development and Evaluation of a Tactilator System

    SBC: AUDIOLOGICAL ENGINEERING CORPORATION            Topic: N/A

    N/A

    SBIR Phase I 1994 Department of Health and Human Services
  7. Development of Artificial, Collagen Based Corneal Grafts

    SBC: Autogenesis Technologies, Inc.            Topic: N/A

    The objective is to develop an artificial full-thickness corneal graft to replace damaged corneain millions of people who suffer from blindness due to damaged or diseased cornea. The specific aimsof Phase I are to fabricate prototype grafts composed of a clear, soluble collagen core surrounded by aperipheral ring, or skirt, containing' intact collagen fibers embedded in soluble collagen. Prelimina ...

    SBIR Phase I 1994 Department of Health and Human Services
  8. Kilolane DNA Sequencer

    SBC: Aztec Systems            Topic: N/A

    This research will investigate the feasibility of a sequencer that can sequence about one millionbases a day. At the heart of the research is etched glass plates that contain channels that will formdiscrete paths for DNA once the two plates are pushed together. Electrostatic gel loading and optimalcharge coupled device (CCD) detection of laser activated fluorescence will be developed. This sequenc ...

    SBIR Phase I 1994 Department of Health and Human Services
  9. Genomic Sequence Search Software for Prophet II

    SBC: Belmont Research, Inc.            Topic: N/A

    Our central goal is to develop easy-to-use software tools, for the PROPHET community, to querythese resources and extract relevant information. The software will provide a modern graphical userinterface and also command-line/scripting tools for specifying the query, and will offer transparentnetwork access for retrieving results. It will incorporate the recently developed NCBI standards forsequenc ...

    SBIR Phase I 1994 Department of Health and Human Services
  10. Software to Measure Ovarian Follicles from Sonography

    SBC: Belmont Research, Inc.            Topic: N/A

    This research will develop new software, to be used with transvaginal ultrasonography, thatwould assist in counting and measuring antral follicles > 2 mm within the ovaries of premenopausalwomen. A computer-assisted method that could quickly and reproducibly quantitate the human ovarianfollicular pool would support physiologic, epidemiologic, and clinical studies of the ovary and couldprovide new ...

    SBIR Phase I 1994 Department of Health and Human Services
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