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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Catheter for Complex Percutaneous Coronary Intervention

    SBC: CROSSLINER INC            Topic: NHLBI

    ABSTRACT Nearly 1 million percutaneous coronary interventions (PCIs) are performed each year in the US. Approximately 70% of these cases are considered complex and require the treatment of calcified lesions, tortuous vessels, and multi-vessel disease, often with total or sub-totally occluded lesions. Many operators avoid these more complex cases, which are often not suitable for radial access appr ...

    SBIR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
  2. Geostatistical software for merging multivariate data with various spatial supports

    SBC: BIO-ANALYTICS, INC.            Topic: R

    7. Project Summary/Abstract A key component in any investigation of association and/or cause-effect relationships between the environment and health outcomes is the availability of accurate models of exposure. Because the cost of collecting field data is often prohibitive, it is critical to incorporate any source of secondary information available to supplement sparse datasets. Secondary data can ...

    SBIR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
  3. Development of a Novel Resolvin-Based Therapy for the Prevention and Treatment of Acute Respiratory Distress Syndrome (ARDS)

    SBC: Thetis Pharmaceuticals LLC            Topic: NIAID

    ABSTRACTAcute Respiratory Distress Syndrome (ARDS) is a life-threatening lung injury characterized by an acute inflammatory response leading to lung and organ failure. It is estimated that up to 190,000 cases of ARDS occur in the US each year resulting in 74,000 deaths. ARDS can be caused by respiratory infections, including COVID- 19, for which it is the leading cause of death. The treatment of p ...

    SBIR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  4. Pediatric ECMO Oxygenator with Integrated Monitoring

    SBC: MICHIGAN CRITICAL CARE CONSULTANTS, INC.            Topic: NICHD

    ABSTRACTExtracorporeal membrane oxygenation (ECMO) is increasingly utilized to provide cardiopulmonary support in patients due to its versatility, immediate benefit, and relatively low cost. However, there continues to be significant morbidity and mortality related to hemostatic complications, especially in the neonatal and pediatric population. A few pediatric oxygenators are used in ECMO; howeve ...

    SBIR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
  5. A therapeutic for Lyme disease based on Peptidoglycan Recognition Protein 1

    SBC: L2 DIAGNOSTICS LLC            Topic: NIAID

    ABSTRACTLyme disease, the most common vector-borne illness in North America, is caused by the spirochete B. burgdorferi. Infection begins in the skin following an infected tick-bite and acute illness is characterized by headache, fever and myalgia. Currently, there is no human vaccine against Lyme disease and therapeutic administration of antibiotics remains the recommended treatment option. In th ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  6. Accurate, High-Throughput, and Affordable Nucleic Acid Sequencing Technology

    SBC: WEDDELL TECHNOLOGIES LLC            Topic: 172

    Project Summary / Abstract Remarkable progress in cancer immunotherapy, and decreasing cost of Next Generation Sequencing (NGS) diagnostics, have sparked clinical tests targeting tumor-immune cell interactions using genomic tools. Non-small cell lung cancer (NSCLC) exemplifies precision medicine with multiple FDA-approved biomarkers. Despite these advancements, the practical use of NGS remains lim ...

    SBIR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  7. DEVELOPMENT OF A FULLY-INTEGRATED CHATBOT TO IMPROVE MEMBER ENGAGEMENT IN ONLINE ADDICTION TREATMENT PROGRAMS

    SBC: WORKIT HEALTH INC            Topic: NIDA

    Project Abstract High attrition and low adherence rates continue to hinder the efficacy of digital addiction treatment programs. When individuals prematurely drop out of treatment programs, they are unable to realize the numerous benefits associated with completing an addiction treatment program, such as fewer relapses and higher levels of employment. Workit Health is developing a fully integrated ...

    SBIR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  8. An Efficacy Trial of a Digital Therapeutic for Suicide Prevention

    SBC: OUI THERAPEUTICS INC            Topic: 104

    ABSTRACT Suicide is one of the top ten causes of death in the US and suicide rates have increased steadily over the last twenty years. Currently, the most effective treatment options are cognitive behavioral therapies for suicide prevention (CBT-SP), which have been shown to reduce both suicide attempt (SA) risk and suicide ideation (SI). However, access to these treatments is limited because ther ...

    STTR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
  9. Development of an AMF Orion/Blackrock HD-USEA based 60/128 channel implantable wireless simulator system for human auditory nerve implants

    SBC: BLACKROCK MICROSYSTEMS, INC            Topic: NIDCD

    Abstract The development of implantable high channel electronics interfacing with the central and peripheral nervous system has been a continuing effort for decades covering a wide range of applications. Reliable and clinically proven high channel solutions with hermetic encapsulation of the electronics that would be suitable for the use in a Cochlear or auditory nerve have so far not been demonst ...

    SBIR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
  10. A peptide-based point-of-care vertical flow assay for the rapid diagnosis of Lyme disease

    SBC: BIOPEPTIDES CORP            Topic: NIAID

    Abstract Project Summary There is an obvious need for new approaches and better assays for the laboratory diagnosis of Lyme disease. All attempts to develop a practical assay for the direct detection of Borrelia burgdorferi in infected patients have failed. Thus far, all proposed alternatives to serology have been unsuccessful, not cost-effective, or are still in early development. Improving serol ...

    SBIR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
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