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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. DEVELOPMENT OF A MIDDLE EAR BALLOON IMPLANT

    SBC: BOSTON MEDICAL PRODUCTS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Development of a new type of middle ear implant, a "middle ear balloon" is proposed. This implant is intended to restore hearing in non-aerated ears by creating and permanently maintaining an air or gas-filled space within the middle ear. Non-aerated middle ears resulting from eustachian tube dysfunction camonly occur in chronic otitis media (COM) and in otitis ...

    STTR Phase II 2002 Department of Health and Human ServicesNational Institutes of Health
  2. Multifunctional Carriers for Systemic siRNA Delivery

    SBC: SURFAGEN, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The objectives of this research project are to design and develop safe and efficient multifunctional delivery systems for systemic and target-specific delivery of small interfering RNA (siRNA) to treat human diseases with RNA interference (RNAi). RNAi is a natural mechanism for gene silencing and has a great potential to treat human disease by turning off speci ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  3. A 3-D Interactive Atlas of the Human Skull

    SBC: BROWN AND HERBRANSON IMAGING            Topic: N/A

    DESCRIPTION (provided by applicant): Broad long term objectives and specific aims: The long-term objective of this project is to develop a digital anatomical research resource library of very high-resolution computational models, and imaging data sets. Our objective is to produce an anatomical library otf the complete human skeleton. The implications of this project, both scientific and social are ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  4. A 3-D Interactive Atlas of the Human Skull

    SBC: BROWN AND HERBRANSON IMAGING            Topic: N/A

    DESCRIPTION (provided by applicant): The principal aim of this project is to develop a resource library of very high-resolution computer models and imaging data sets of human skulls. This skull database project, which builds upon and is an extension of the Tooth Atlas project, will be the first phase of a complete, whole body, osteology library. As the imaging and computer technology advances, th ...

    STTR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  5. Validation and Quantification of FFPE Antigen Retrieval by Proteome Analysis

    SBC: CALIBRANT BIOSYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Because of the long history of the use of formalin as the standard fixative for tissue processing in histopathology, there are a large number of archival formalin-fixed and paraffin-embedded (FFPE) tissue banks worldwide. These FFPE tissue collections, with the attached clinical and outcome information, present invaluable resources for conducting retrospective ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  6. VALIDATION AND QUANTIFICATION OF FFPE ANTIGEN RETRIEVAL BY PROTEOME ANALYSIS

    SBC: CALIBRANT BIOSYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Because of the long history of the use of formalin as the standard fixative for tissue processing in histopathology, there are a large number of archival formalin-fixed and paraffin-embedded (FFPE) tissue banks worldwid e. These FFPE tissue collections, with attached clinical and outcome information, present invaluable resources for conducting retrospective pro ...

    STTR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  7. OVARIAN CANCER PROTEOME VIA TISSUE MICRODISSECTION AND GEMINI TECHNOLOGIES

    SBC: CALIBRANT BIOSYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Biologically and clinically relevant proteomics data can only be generated if organ or tissue samples investigated consist of homogeneous cell populations, in which no unwanted cells of different types and/or developmen t stages obscure the results. Thus, several tissue microdissection technologies have been developed to provide a rapid and straightforward meth ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  8. IDENTIFICATION AND EXPRESSION OF INSECTICIDE TARGETS

    SBC: CAMBRIA BIOSCIENCES, LLC            Topic: N/A

    DESCRIPTION (Provided by applicant): Insect-borne infectious diseases such as malaria affect at least 1 billion people worldwide, and over 1.5 million of these infected individuals die each year. Malarial parasites and many other vector-borne pathogens have developed resistance to current drugs, and vaccines are not available or feasible for many of these pathogens. Insect vector control programs ...

    STTR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  9. Monoclonal Antibodies Against T-Regulatory Cells

    SBC: CANCER THERAPEUTICS LABORATORIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Immunotherapy is a powerful therapeutic modality that has great potential for the treatment of cancer. Considering the lack of options which exist for patients with refractory solid tumors, immunotherapy could provide patients with an alternative treatment that may be used in conjunction with existing therapies. In the last several years, it has become appar ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  10. GENETICALLY ENGINEERED STREPTAVIDINS

    SBC: CAPTEC, LLC            Topic: N/A

    N/A

    STTR Phase I 1998 Department of Health and Human Services
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