Award Data

DESCRIPTION (provided by applicant): Genital herpes is one of the most prevalent sexually transmitted infections worldwide and is associated with substantial morbidity. The impact of genital herpes as a public health threat is amplified because of its epidemiologic synergy with HIV. Epidemiological studies consistently demonstrate that HSV infection increases the risk of HIV transmission and acqu ...

DESCRIPTION (provided by applicant): The goals of this proposal are to devise rapid serological tests that can replace the sputum smear test for the diagnosis of active TB and meets the WHO specifications to replace microscopy in resource-limited countries based on immunodominant peptides from three M. tb cell-wall proteins. Although direct smear microscopy is highly specific, the test is tedious, ...

In this Small Business Technology Transfer Program (STTR) - Phase II project we will build photonic integrated circuits that perform flip-flop and optical switching operations on silicon platform. These circuits are based on our Phase I work where we have established the feasibility of using coupled microdisk resonators and active waveguides coupled to a single microring resonator to realize bista ...

This STTR Phase II project will develop novel engineered Clostridia strains for fermentation and economically produce butanol as a biofuel from sugars derived from starchy and lignocellulosic biomass. The conventional acetone-butanol-ethanol (ABE) fermentation has low butanol yield (

In this Phase I STTR, Illuminaria, in collaboration with Professor Erickson’s Laboratory at Cornell University, designed and developed a practical liquid based reconfigurable photonic device photonic switch using low voltage microfluidic pumps and microfabricated optofluidic waveguides. Briefly, the basic element of this approach comprises a stream of high index of refraction liquid (core) micr ...

This Small Business Technology Transfer (STTR) Phase II project is a study to expand the high speed addressing work conducted under Phase I using monochrome Plasma-spheres to color Plasma-spheres. Plasma-spheres are hollow transparent shells that encapsulate a selected pressurized gas. When a voltage is applied across the shell, the gas ionizes and glows. Plasma-spheres are applied to flexible, el ...

The proposed work seeks to clearly demonstrate the advantage of the multiple-input multiple-output (MIMO) radar architecture over a similar single-input multiple-output (SIMO) or phased array system; the benefit of applying data-adaptive signal processing techniques in favor of their data-independent counterparts; and the utility of transmitting advanced probing waveforms as opposed to conventiona ...

If a computer system suffers a cyber attack, any compromised component that is simply reinstalled will remain vulnerable to the attack that damaged it; so replacements should provide equivalent services implemented differently. This defense can be applied proactively, to create a"moving target"by periodic reconfiguration. Implementing these strategies requires an effective way to create diversity. ...

The objective of this research is to advance technologies for accurately and reliably characterizing the distributed fields within Naval aircraft and the associated currents on avionic systems and their interconnecting cables in the operational electromagnetic (EM) environment. This includes computing the fields and currents within aircraft cockpits, cabins and equipment bays at/near metallic wall ...

The 3-D SAR imaging of objects in a scene provides improved military target identification and weapons targeting accuracy. This capability can also potentially be combined with simultaneous SAR/GMTI surveillance modes to provide 3-D context information for moving targets in a scene. In Phase I, TSC demonstrated a promising approach for noncoherently combining 3-D tomographic SAR images generated f ...