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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Exemplar-Based Medical Text Classification

    SBC: Belmont Research, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1994 Department of Health and Human Services
  2. Cesium-131 Sources for Brachytherapy

    SBC: Best Industries, Inc.            Topic: N/A

    Low energy X and Gamma ray sources such as Cs-131 (9.7 Days T1/2, 30 keV) are extremelyuseful in cancer therapy with obvious advantages such as ease of shielding, useful range in tissue. SinceCs-131 is capable of forming insoluble metal complexes with metal salts such as AmmoniumMolybdophosphate, it is intended to exploit this property of Cesium in this study. The purpose of thepresent study is to ...

    SBIR Phase I 1994 Department of Health and Human Services
  3. Islet Transplantation Using Implantable Microreactors

    SBC: BioHybrid Technologies Inc.            Topic: N/A

    N/A

    SBIR Phase I 1994 Department of Health and Human Services
  4. Carbon 13 Lipids, Oral Absorption in Cystic Fibrosis

    SBC: Biomolecular Products, Inc.            Topic: N/A

    Cystic fibrosis (CF) is a lethal disease with a median survival age of 29 years in 1991. Increasedsurvival is associated with a more normal growth curve. However, growth failure continues to be aproblem; for example, approximately 40% of the CF individuals in 1990 were below the 5th percentilefor normal weight and height. The nutritional deficit in CF is associated with pancreatic insufficiencyand ...

    SBIR Phase I 1994 Department of Health and Human Services
  5. Early Diagnosis of Mucosal Cancer by Confocal Scanning

    SBC: MEDISPECTRA, INC.            Topic: N/A

    Tumors originating in the mucosa account for more than half of all cancer deaths in the US;therefore, early detection is important. We will apply a novel technique to real-time diagnosis andassessment of precancerous growth and early cancer of the mucosa, by measuring its fluorescenceindependently of the much stronger submucosal fluorescence. Fluorescence and scatteringmeasurements of the lining o ...

    SBIR Phase I 1994 Department of Health and Human Services
  6. Multidose Dispenser for Unpreserved Ophthalmic Solutions

    SBC: BIOPOLYMERIX, INC.            Topic: N/A

    N/A

    SBIR Phase I 1994 Department of Health and Human Services
  7. Hydroformed Microspheres as New Injectable Drug Vehicle

    SBC: BIOTEK, INC.            Topic: N/A

    We have developed a new hydroforming process for making sustained release injectablebiodegradable microsphere and microcapsule well suited for delivery of water soluble drugs such aspeptides and proteins. The process incorporates drug into hydroformed microspheres made of sparinglysoluble calcium minerals, such s calcium sulfate, which can then be overcoated with a polymer, mineralor lipid shell. ...

    SBIR Phase I 1994 Department of Health and Human Services
  8. Buprenorphine For Transdermal Analgesia

    SBC: BIOTEK, INC.            Topic: N/A

    We will demonstrate the practical feasibility of transdermal analgesic therapy based onbuprenorphine, a potent opioid already used intravenously and intramuscularly for the relief of moderateto severe pain. Preliminary in vitro experiments have confirmed that buprenorphine can pass throughhuman skin at potentially therapeutic rates. Using BIOTEK's patented DermaPatch transdermal systemit should be ...

    SBIR Phase I 1994 Department of Health and Human Services
  9. New assays for Pathogens Relevant to Blood Transfusion

    SBC: BIOTRACES, INC.            Topic: N/A

    The strategy for highly parallel screening of blood borne pathogens is proposed. Constituentsteps are simultaneous collection of all suspect pathogens on magnetic beads coated with correspondingantibodies. The polymerase chain reaction (PCR) is then used to amplify different length, targetedsegments of the proposed pathogens genomes. The primers carry PG and/or EC isotopic labelsincorporated. The ...

    SBIR Phase I 1994 Department of Health and Human Services
  10. New Assays for Methylation Patterns in Cancer

    SBC: BIOTRACES, INC.            Topic: N/A

    The Genomic Walking strategy is currently the only sequencing method sensitive to methylationpatterns and thus should be used to detect methylated residues. The current implementation of the GWstrategy is limited by the sensitivity of the autoradiography used to image the sequencing blots (about10[-17] moles per sequencing band). The use of a spatially resolving MPD system (that has a provenresolu ...

    SBIR Phase I 1994 Department of Health and Human Services
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