You are here

Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Developing novel technologies to monitor nociception and opioid administration during surgery and general anesthesia in order to minimize post-operative opioid requirements

    SBC: PASCALL Systems, Incorporated            Topic: NIDA

    PROJECT SUMMARY In light of the opioid crises, minimizing postoperative pain and postoperative opioid requirements to reduce chronic opioid dependency among surgical patients have become major concerns for surgeons and anesthesiologists. Effective intraoperative nociception control can mitigate these concerns. Unfortunately, existing nociceptive monitoring tools use indicators that are inherently ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  2. Using Targeted Lipid Nanoparticles to Deliver Chemotherapeutic Agents againstPancreatic Cancer

    SBC: Doric Pharma            Topic: 102

    PROJECT SUMMARY/ABSTRACT Pancreatic cancer continues to be a devastating disease with less than 10% 5-year survival. Pancreatic cancer is aggressive and there are no good tools for early detection. By the time of diagnosis, the tumor is often surgically unresectable. At this stage, patients are often treated with different chemotherapeutic agents or their combination, which while potent, have sign ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  3. A Novel Strategy for Diagnosis of Esophageal Adenocarcinoma.

    SBC: CAPSULOMICS INC            Topic: 102

    Contact PD/PI: Abraham, John M Esophageal adenocarcinoma (EAC) is one of two major types of esophageal cancer, which causes 509,000 deaths worldwide annually. EAC diagnosis is made using the invasive, expensive, risky, and not universally accessible procedure, esophagogastroduodenoscopy (EGD). Thus, there is a pressing need for easier, safer, cheaper strategies for EAC diagnosis. Our novel strateg ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  4. Unbiased longitudinal neuromorphometry for clinical decision support

    SBC: CORTICOMETRICS LLC            Topic: NIA

    Project Summary Normal human neuroanatomy is incredibly variable, and increases with age. This impedes the ability of neuroimaging to detect effects in neurological conditions such as Alzheimerandapos;s disease (AD), Huntingtonandapos;s disease (HD), multiple sclerosis (MS) and schizophrenia. Most of the recently available state-of-the-art quantitative imaging tools still use cross-sectional metho ...

    STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  5. Marburg Virus Prophylactic Medical Countermeasure

    SBC: Flow Pharma, Inc.            Topic: CBD18A002

    Through this STTR contract, we propose to evaluate the efficacy of our vaccine, FlowVax Marburg, in nonhuman primates (NHPs). This will be achieved through four Tasks. In Task 1, we will manufacture the vaccine in a quantity sufficient for the animal studies. In Task 2, we will perform MHC genotyping on a representative population of NHPs and, based on results, select a set of MHC-matched NHPs for ...

    STTR Phase II 2020 Department of DefenseOffice for Chemical and Biological Defense
  6. Marburg Virus Prophylactic Medical Countermeasure

    SBC: MAPP BIOPHARMACEUTICAL, INC.            Topic: CBD18A002

    There are currently no vaccines or therapeutics available for Marburg Virus Disease (MVD). Given the specter of weaponization and the terrible morbidity and high mortality rate of MVD, this represents a critical threat to the operational readiness of the Warfighter. While traditional vaccines have contributed greatly to public health, they have some limitations especially in the context of operati ...

    STTR Phase II 2020 Department of DefenseOffice for Chemical and Biological Defense
  7. Aminonaphthyridine compounds as potential therapeutics for lung and thyroid cancers

    SBC: KINARX, INC            Topic: 102

    Over the past three decades a growing number of cancer-driving protein kinases have been successfully targeted as reflected in the approval of 49 kinase inhibitors by the Food and Drug Administration (FDA). Recent approval of the first tyrosine kinase inhibitor (Larotrectinib) for treatment of any cancer bearing mutation in neurotrophic receptor kinase validated a novel paradigm of precision targe ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  8. Bounding generalization risk for Deep Neural Networks

    SBC: EULER SCIENTIFIC            Topic: NGA20A001

    Deep Neural Networks have become ubiquitous in the modern analysis of voluminous datasets with geometric symmetries. In the field of Particle Physics, experiments such as DUNE require the detection of particle signatures interacting within the detector, with analyses of over a billion 3D event images per channel each year; with typical setups containing over 150,000 different channels.  In an ...

    STTR Phase I 2020 Department of DefenseNational Geospatial-Intelligence Agency
  9. Spray-based visual indicator of opioids for the rapid and effective decontamination of large areas

    SBC: TRITON SYSTEMS, INC.            Topic: CBD20AT001

    Triton Systems, Inc. will collaborate with The University of Massachusetts Lowell to develop a spray-based technology for the rapid, visual identification of opioids, turning contaminated areas from nondescript white powders to a brightly colored spots for easy recognition with the naked eye. The technology leverages molecular recognition units that bind strongly and specifically to a variety of o ...

    STTR Phase I 2021 Department of DefenseOffice for Chemical and Biological Defense
  10. Eye-readable Solution-based Dye Displacement Probe for Large-area Detection of Opioids

    SBC: INTELLIGENT OPTICAL SYSTEMS, INC.            Topic: CBD20AT001

    Intelligent Optical Systems, Inc., in collaboration with Bowling Green State University, proposes to develop a field-rugged, eye-readable indicating spray solution that can immediately detect synthetic opioids over a large area of contamination (i.e., military vehicles, individual protective equipment, clandestine labs, etc.). The proposed chemosensor in a spray solution format will detect multipl ...

    STTR Phase I 2021 Department of DefenseOffice for Chemical and Biological Defense
US Flag An Official Website of the United States Government