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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Development of an Electromyographically Controlled Electrolarynx Voice Prosthesis

    SBC: GRIFFIN LABORATORIES, INC.            Topic: NIDCD

    DESCRIPTION (provided by applicant): The most common artificial voice source for post-laryngectomy speech rehabilitation is the hand-held buzzer or electrolarynx (EL). This device is relatively easy to use and enables most laryngectomees to verbally communicate, but with reduced intelligibility and markedly degraded naturalness. In addition, EL speech is often described as robotic and monotone, at ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  2. Lentiviral gene therapy for mucopolysaccharidosis

    SBC: LENTIGEN CORPORATION            Topic: NIDDK

    DESCRIPTION (provided by applicant): Mucopolysaccharidosis type II (MPS II, Hunter syndrome) is an X-linked recessive inherited disorder caused by absence of iduronate-2-sulfatase, resulting in systemic accumulation of glycosaminoglycans heparan sulphate and dermatan sulphate. Affected individuals suffer from skeletal abnormalities, organomegaly, life- threatening obstructive airway disease, and, ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  3. Bio-monitoring Methylene Diphenyl Diisocyanate (MDI) exposure and body burden

    SBC: L2 DIAGNOSTICS LLC            Topic: NIEHS

    DESCRIPTION (provided by applicant): Exposure to isocyanate, the essential cross-linker for making polyurethane, is a leading cause of occupational asthma world-wide. Three major types of isocyanate are used commercially, methylene-diphenyl diisocyanate (MDI) and toluene diisocyanate (TDI), or aliphatic, hexamethylene diisocyanate (HDI). Despite being the newest of the three, MDI has overtaken th ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  4. Enhanced Liquid Core Waveguide Biosensor for PBDE Detection

    SBC: SYNTHIA, LLC            Topic: NIEHS

    DESCRIPTION (provided by applicant): Polybrominated diphenyl ethers (PBDEs) are common flame retardants used to reduce the risk of fire in a wide variety of products, such as mattresses, furniture, home electronics, textiles, upholstery fabrics, carpet, and children's toys. As a consequence, wide spread occurrence in the environment and bioaccumulation through various exposure routes have been rev ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  5. PROOF OF CONCEPT FOR ANTIMICROBIAL PROPERTIES OF LACRITIN IN VIVO

    SBC: EYERX RESEARCH, INC.            Topic: NEI

    DESCRIPTION (provided by applicant): Over the past sixty years, antibiotics have comprised a key component in both the treatment and prophylaxis of bacterial infections. Since that time the continuous development of new antibiotics has been necessary to limit toxicity, promote broader spectrum therapy, increase convenience of use, and decrease the time to clear the infection. Another driving force ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  6. Characterization of Exudative Macular Degeneration and Diabetic Retinopathy Using

    SBC: VISDEX CORP            Topic: NEI

    DESCRIPTION (provided by applicant): Since its first use in the retina in 1961, fluorescein angiography (FA) has been the gold standard for objective characterization of retinovascular disease (e.g. diabetic retinopathy, retinal vein occlusions, and choroidal neovascularization associated with age-related macular degeneration (AMD)). Despite its widespread use, FA is costly, invasive, and time con ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  7. Learning System for Continuous Professional Education in Low Vision Rehabilitatio

    SBC: Emerald Events, Inc.            Topic: NEI

    Emerald Education Systems has developed an online continuing professional education learning system that targets low vision rehabilitation service providers. This CE learning system has three components: 1) a set of coordinated in depth online courses that provide a broad and deep foundation of knowledge on low vision rehabilitation that is delivered using a didactic approach at a learner-controll ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  8. Numerical Tools for Predicting Drug Dissolution Profiles

    SBC: RES Group, Inc.            Topic: NIGMS

    DESCRIPTION (provided by applicant): This STTR Phase I proposal describes the development of a modeling framework that combines a mesoscopic model for hydrodynamics with dissolution kinetic models in order to accurately describe the dissolution behavior of drugs. The complexities of the drug dissolution problem have led to the development of empirical methodologies being the widespread practice in ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  9. Improve Wound Healing with HIF-CA5 DNA Vector and Electroporation

    SBC: CANTON BIOTECHNOLOGIES, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Therapy to Improve Wound Healing with DNA Expression Vector for HIF 11 and Electroporation Impaired wound healing is a tremendous problem for individuals with diabetes. Patients with diabetes are at risk for developing foot ulcers. These non-healing ulcerations on the foot are disabling, and their progression leads to amputation of the lower extremity. Diabetes ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  10. Vaginal Ring for Preventing Bacterial Vaginosis

    SBC: REPROTECT, LLC            Topic: NICHD

    DESCRIPTION (provided by applicant): Bacterial Vaginosis (BV) is an exceptionally common vaginal condition in which robust lactobacillus microflora in the vagina is replaced by a dense polymicrobial overgrowth. At any given time, about 1 in 3 women in the U.S. have BV; half are asymptomatic, and most women with symptomatic BV have only mild symptoms (increased discharge with a fishy smell). Despit ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
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