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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Sorting live cells using RNA-targeting CRISPR-Cas9 (RCas9)

    SBC: DAHLIA BIOSCIENCES, INC.            Topic: 172

    Project Summary/Abstract Transcriptomic-based approaches, and in recent years, single-cell RNA sequencing, are revolutionizing our understanding of cellular heterogeneity, opening up a new route to identify novel cell markers at unprecedented scale across many different cell types. ​RNA-based live-cell sorting opens up andgt;99% of the marker space to enable higher specificity cell sorting. Howe ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  2. SoundTrak: A Data Acquisition and Analysis System for OSDB

    SBC: BARRON ASSOCIATES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Obstructive sleep-disordered breathing (OSDB) is common in children and is now recognized as having substantial neurocognitive, neurobehavioral, and cardiovascular consequences. There are major limitations in diagnosing OSDB in children, who often do not have discrete apneas or hypopneas that can be diagnosed by measurement of airflow. Instead, children often h ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  3. SoundTrak: A Data Acquisition and Analysis System for OSDB

    SBC: BARRON ASSOCIATES, INC.            Topic: NICHD

    DESCRIPTION provided by applicant Obstructive sleep disordered breathing OSDB is common in both children and adults and is recognized as having substantial health related consequences at all ages Laboratory polysomnography PSG is the gold standard for diagnosing OSDB but the procedure is not without problems Polysomnographic studies are complex invasive expensive not universally avail ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  4. SoundTrak Data Acquisition and Analysis System for OSDB

    SBC: BARRON ASSOCIATES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Snoring, a symptom of increased upper airway resistance during sleep, is extremely common in children. Such obstructive sleep disordered breathing (OSDB) is now recognized as having substantial neurocognitive, neurobehavioral, and cardiovascular consequences. One of the major limitations in diagnosing OSDB is the need for relatively complex, burdensome, and cos ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  5. Spectroscopic identification /removal of PMMA from bone

    SBC: Remspec Corp            Topic: N/A

    DESCRIPTION (provided by applicant): The objective is to develop a fiber optic-based, real-time, in-situ method for distinguishing bone from polymethyl methacrylate (PMMA) cement during replacement hip arthroplasty surgery. The proposed method is based on near-infrared (NIR) spectroscopy, which has been shown to be a viable method for distinguishing bone and PMMA in the laboratory. The program is ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  6. Speech Enhancement Based on Auditory Coding of Voiced Signals

    SBC: OMNISPEECH, LLC            Topic: NIDCD

    DESCRIPTION provided by applicant The greatest challenge to auditory communication is background noise especially in the complex acoustic environments that are experienced in daily life This project proposes to develop a novel speech enhancement algorithm that is robust in the presence of everyday environmental interference The algorithm is inspired by recent findings related to the neural c ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Spinal Fusion Using Adipose Derived Adult Stem Cells

    SBC: Cognate Therapeutics, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Back pain afflicts over 75% of Americans during their lifetime and 2% of the American work force suffers a back injury on the job each year. Spinal fusion is the orthopedic procedure routinely used to treat back pain in patients suffering from degenerative disc disease, spinal stenosis, scoliosis, and spinal fracture; however, procedure failure rates range betw ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  8. SPNS2 inhibitors as renal fibrosis therapy

    SBC: Flux Therapeutics, LLC            Topic: 400

    Fibrosis is an aberrant wound healing process characterized by progressive accumulation of extracellular matrix that ultimately destroys organ function. Progressive fibrosis is inherent to chronic kidney disease (CKD), which often leads to end-stage renal disease. Although patients can be maintained by hemodialysis while awaiting transplantation, their’s and their care-giver’s quality of life ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  9. Spray-based visual indicator of opioids for the rapid and effective decontamination of large areas

    SBC: TRITON SYSTEMS, INC.            Topic: CBD20AT001

    Triton Systems, Inc. will collaborate with The University of Massachusetts Lowell to develop a spray-based technology for the rapid, visual identification of opioids, turning contaminated areas from nondescript white powders to a brightly colored spots for easy recognition with the naked eye. The technology leverages molecular recognition units that bind strongly and specifically to a variety of o ...

    STTR Phase I 2021 Department of DefenseOffice for Chemical and Biological Defense
  10. Stabilization of Therapeutic Peptides by Non-Perturbative Chemical Modification

    SBC: VERAQUEL TECHNOLOGIES, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Type 2 diabetes is a particularly debilitating disease and is endemic for a large proportion of the world's population. The unmet challenges in disease management are the lack of long-term efficacy in reducing hyperglycemia and the inability to stop progression. Glucagon-like peptide-1 (GLP-1), a natural gut hormone, provides a platform for therapeutics to ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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