Award Data

The innovation proposed in this Small Business Innovation Research Phase II project will harness the popularity and ubiquity of mobile microgames on hand-held devices for educating children on self-management of chronic health conditions. Millions of children suffer from chronic conditions which require regular management, such as diabetes, or from broader states of poor health caused by obesity. ...

This Small Business Technology Transfer (STTR) Phase II project will develop a multi-functional active fiber Bragg grating sensor technology for the monitoring and management of cryogenic fuel such as liquid hydrogen and liquefied natural gas. The proposed technology uses in-fiber light to actively adjust sensor temperature, which will drastically improve responsivity and sensitivity of fiber sens ...

TBD

Today the evaluation methods employed in the development and assessment of soldier borne Personal Protective Equipment (PPE) system designs are often extremely slow, expensive, and subjective, resulting in significant delays and expense in the fielding of improved designs. Recent rapid advancements in digital human modeling now allow the development of a multi-scale, comprehensive PPE evaluation t ...

Ischemic stroke is a leading cause of death and disability in the United States. This often is attributable to thrombus formation at an atherosclerotic plaque or thromboembolism. Patients who present within 4.5 hours of symptom onset are eligible for thrombolysis with tissue plasminogen activator (tPA). This serves andlt;5% of victims. Recently, major advance has been made with proven efficacy fro ...

DESCRIPTION (provided by applicant): Over the past decade, an investigation of how family members talk through cancer on the telephone has resulted in the recent publication of a lengthy volume entitled A Natural History of Family Cancer: Interactional Resources for Managing Illness (NH). Based on the conversations analyzed for this volume, and related research on the psychosocial impacts and con ...

Decontamination of chemical and biological threats demands a very reactive solution. It is ideal to generate the decontaminants on-site: the activated decontaminant is highly reactive and quickly destroys chemical and biological warfare agents; prior to activation the ingredients can be safely stored for years, shipped, and handled. TDA's electrochemical decontamination (eClO2) technology u ...

DESCRIPTION (provided by applicant): Diabetes mellitus (DM) leads to a 3-4 fold higher risk of experiencing ischemic stroke. In addition, DM stroke patients are more prone to develop more and earlier white matter (WM) high-intensity lesions than non DM stroke patients. Treatment of stroke with tissue plasminogen activator (rtPA) at 2-3 hours after stroke decreases lesion volume in non-DM rats. How ...

DESCRIPTION (provided by applicant): Image-based evaluation of pathologies over time is complicated by variability in image acquisition and patient positioning, deformations due to respiratory and cardiac motion, and the clinical standard in radiology of comparing unaligned images. This application proposes a computational method for longitudinal image analysis that captures, illustrates and quant ...

DESCRIPTION: New therapeutic agents are urgently needed for the treatment of sickle cell disease (SCD), the world's most common genetic disease. Our long-term goal is to develop a drug for use in children that prevents the inexorable progression of SCD. SCD affects approximately 100,000 people in the United States and millions worldwide. It kills more children in Africa than HIV, but while HI ...