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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Star-dots fluorescent nanoparticles for flow cytometry and biomedical imaging

    SBC: Nanoscience Solutions, LLC            Topic: NIAID

    Fluorescent nanoparticlesFNPare becoming increasingly popular in biomedical imaging and taggingCompared to molecule based fluorophoresFNP are typically brighter and more photostableThey can be functionalized with more than one tagging moleculeused for the tagging and tracing of specific moleculescellstissuesBrighter fluorescence facilitates more sensitive labelingand in many casesa lower limit of ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Stimulation of Tear Secretion by a Novel Glycoprotein

    SBC: EYERX RESEARCH, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Dry eye is a ubiquitous, often overlooked, underdiagnosed and poorly understood affliction of the ocular surface. This common opthalmological complaint can markedly affect a patient's quality of life. As a multifactorial disease, dry eye has hyposecretory, auto-immune, inflammatory, hormonal, neurogenic, toxic, and iatrogenic components. Common to all etiologie ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  3. Stimulation of Tear Secretion by a Novel Glycoprotein

    SBC: EYERX RESEARCH, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Description Dry eye is a ubiquitous, often overlooked, under diagnosed and poorly understood affliction of the ocular surface. As a multifactorial disease, dry eye has hyposecretory, auto-immune, inflammatory, hormonal, neurogenic, and iatrogenic components. Common to all etiologies is a decrease of both volume and quality of tear secretion. There are currently ...

    STTR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  4. Strength and BALance (SABAL) Virtual Trainer

    SBC: BARRON ASSOCIATES, INC.            Topic: NIA

    DESCRIPTION provided by applicant Introduction The Strength and BALance SABAL program targets reduction of fall risk in older adults through fun meaningful and motivating games that incorporate evidence based exercises and automatic generation of fall risk metrics The product consisting of virtual world based gaming software and an off the shelf KinectTM sensor will be used in senior ce ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Structure guided rational engineering of novel DNA reagents.

    SBC: NEW ENGLAND BIOLABS, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Type II restriction enzymes (REases) are indispensible tools of modern medical research. It has long been a goal of REase manufacturers to be able to offer programmable specificity enzymes, where the sequence recognizedand resulting cutting activity can be precisely directed to any desired point in a DNA, as this will offer opportunity for improvement in many a ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  6. Structure guided rational engineering of novel DNA reagents.

    SBC: NEW ENGLAND BIOLABS, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Type II restriction enzymes (REases) are indispensible tools of modern medical research. It has long been a goal of REase manufacturers to be able to offer programmable specificity enzymes, where the sequence recognizedand resulting cutting activity can be precisely directed to any desired point in a DNA, as this will offer opportunity for improvement in many a ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  7. STTR: Herpes Based RNAi Vectors

    SBC: SIMPLX PHARMACEUTICALS            Topic: N/A

    DESCRIPTION (provided by applicant): Chronic pain and hypersensitivity associated with inflammation affects millions of Americans. Recently, it has become apparent that a critical mechanism in developing and maintaining inflammatory pain is the overexpression of certain sodium channels in the sensory neurons that innervate the inflamed tissue. Thus, pharmaceutical companies have for some years att ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  8. Study of CdZnTe Electrode Interface and Fabrication Technology Development

    SBC: Aguila Technologies, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): In several recent PA's, the NIH has articulated a clear vision for the future of medical imaging systems a) enhanced spatial or temporal resolution, b) better sensitivity and specificity, c) multi-modality, and d) new functional or molecular imaging or spectroscopy methods. Owing to their unique combination of properties, direct conversion gamma radiation imagi ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  9. Study of CdZnTe Electrode Interface and Fabrication Technology Development

    SBC: Aguila Technologies, Inc.            Topic: N/A

    Not avaiable.

    STTR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  10. Substance Abuse Diagnostic Clinical Interview Simulation

    SBC: SIMMERSION LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Traditional methods for training clinicians and students in mental health disciplines in substance abuse assessment have been restricted to role-playing, mock interviews, textbook lessons, and video instruction. All of these tools have limitations for imparting real world experiences. Specifically, traditional methods of instruction do not include realistic in ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
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