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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Hydroxyl radical mapping of protein interfaces

    SBC: EXSAR CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Identifying amino acid residues of a protein that form the binding site for a drug, or that are present at the interface in a protein-protein complex are difficult to identify from the crystal structures of the individual partner proteins. Carta Proteomics is committed to the premise that monitoring isotope exchange in ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  2. Optimum Dose of rhCC10 for Lung Protection in IRDS

    SBC: CLARAGEN, INC.            Topic: N/A

    DESCRIPTION (Scanned from the applicant's description): The proposed study involves an evaluation of the dose response to recombinant human CC10 in the preterm lamb, a surfactant-dependent model of neonatal/infant respiratory distress syndrome (IRDS). The preterm lamb model was used in the clinical development of artificial surfactants for the treatment of I ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  3. Parametric models for survival analysis

    SBC: EPICENTER SOFTWARE            Topic: N/A

    DESCRIPTION (provided by applicant): The most commonly used statistical methods for the design and analysis of cancer clinical trials today rely heavily on the idea of proportional hazards or its generalizations; i.e., that the important differences between treatments are reflected in the differences between failure rates. Implicit in the use of these methods is the assumptio ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  4. SOD/Catalase mimics for age-related learning impairment

    SBC: Eukarion, Inc.            Topic: N/A

    DESCRIPTION Adapted from applicant's abstract): Aging is accompanied by a slow decline in cognitive function, now referred to as mild cognitive impairment (MCI), and by accumulation of oxidized proteins and lipids as a result of oxidative stress. Eukarion has discovered a new class of manganese complexes that display both superoxide dismutase (SOD) and catalase ac ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  5. Aerosolized hyaluronic acid as a treatment for emphysema

    SBC: EXHALE THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Chronic obstructive pulmonary disease afflicts 12-14 million people in the US and in an advanced form, emphysema, disables 2 million and ultimately leads to death. No approved, existing treatment can arrest emphysema's progressive destruction of the lung. Exhale Therapeutics, Inc intends to develop and commercialize aeros ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  6. In Silico Prediction of Metabolic Gene Expression Patter

    SBC: GENOMATICA, INC.            Topic: N/A

    The recent explosion of biological information now available to researchers at all levels of biological investigation has resulted in-part from high-throughput technologies to sequence genes and proteins, and to determine their expression patterns, in an attempt to capture the algorithmic complexity of biological functions. Collectively, this data has begun to enable the study of cells as living s ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  7. Combinatorial Carbohydrate Libraries for Drug Discovery

    SBC: IBIS BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Development of new antimicrobial compounds is urgently needed as bacteria evolve resistance to the antibiotics of last resort. The long-term objective of this proposal is to identify new carbohydrate-based compounds that bind to the small ribosomal subunit and specifically alter bacterial translation. Five hundred new a ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  8. HOMOGENEOUS MULTIPLEX PCR BY FLUORESCENCE AND TM

    SBC: IDAHO TECHNOLOGY            Topic: N/A

    DESCRIPTION (applicant's abstract): Our long-term goal is to advance techniques and instrumentation for rapid, automated analysis of nucleic acids during amplification. Our approach is to add fluorescent probes before amplification and analyze the results in real-time, completing the entire process in 10-20 min. No additional sample processing, membranes, arrays, or ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  9. HOMOGENEOUS MULTIPLEX PCR BY FLUORESCENCE AND TM

    SBC: IDAHO TECHNOLOGY            Topic: N/A

    DESCRIPTION (applicant's abstract): Our long-term goal is to advance techniques and instrumentation for rapid, automated analysis of nucleic acids during amplification. Our approach is to add fluorescent probes before amplification and analyze the results in real-time, completing the entire process in 10-20 min. No additional sample processing, membranes, arrays, or ...

    STTR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  10. High Resolution Fluorescent Melting Curve Analysis

    SBC: IDAHO TECHNOLOGY            Topic: N/A

    DESCRIPTION (Applicant's abstract): Our long-term goal is to advance instrumentation and techniques for rapid, automated and sensitive variant analysis of nucleic acids. The LightCyclerTM has been our homogenous "closed system" platform for genotyping. Fluorescent hybridization probes are included at the beginning of the reaction and are used for realtime P ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
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