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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. N/A

    SBC: VERACHEM LLC            Topic: N/A

    N/A

    STTR Phase I 2000 Department of Health and Human ServicesNational Institutes of Health
  2. DEVELOPMENT OF NUCLEAR TARGETING DNA VACCINE VECTORS

    SBC: VICAL, INC.            Topic: N/A

    N/A

    STTR Phase I 1999 Department of Health and Human Services
  3. Nanostenting Hydrogels for Sinus Surgery

    SBC: RECOGNITION ROBOTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Chronic sinus disease affects over 31 million Americans, and surgery for this disease is performed over 200,000 times annually. Success in functional endoscopic sinus surgery (FESS) is frequently limited by poor wound healing and scar contracture. Sentrx Surgical, Inc., a University of Utah startup formed to commercialize in situ crosslinkable glycosaminogly ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  4. Thiol-Reactive Crosslinkers for Biomaterials

    SBC: RECOGNITION ROBOTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): A limited number of cytocompatible crosslinkers are available for the preparation of cell-seeded hydrogels and in vivo biocompatible injectable biomaterials. To expand this selection, Sentrx Surgical, Inc. will synthesize and evaluate a series of thiol-reactive bivalent and polyvalent crosslinkers based on polyethylene glycol (PEG). We will determine the relati ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  5. Crosslinkable Hydrogels for Tympanic Membrane Repair

    SBC: RECOGNITION ROBOTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Tympanic membrane perforation (TMP, or "ruptured eardrum") is a common occurrence caused by trauma, ear infections, or pressure equalization tube insertion. TMP may cause significant hearing loss or a portal for water exposure or infection. Current treatment uses a patient's own adipose or soft tissue to provide a template for repair of the perforation, often r ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  6. Biomaterials for Adhesion-Free Tendon Repair

    SBC: RECOGNITION ROBOTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The formation of adhesions following flexor tendon surgery in the hand is a common post-operative complication. Adhesions can severely impair the function and range of motion of the affected digit and can cause the partial loss of hand function. Injection of hyaluronan (HA) or insertion of barriers prepared from chemically-modified HA are currently used to redu ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  7. An In Vitro Assay for Screening Chemicals Interacting with the Blood-Brain Barrie

    SBC: IN VITRO ADMET LABORATORIES, LLC            Topic: NIEHS

    DESCRIPTION (provided by applicant): The objective of our grant application is to develop an in vitro model of the blood-brain barrier and assays to examine permeability by using isolated brain microvessels. Unlike capillaries in other organs, brain capillaries establish a barrier that is largely impermeable to polar and larger chemicals, which are due to tight junctions, the absence of both f ...

    STTR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  8. Targeted Polymeric Combination Delivery for Treatment of Ovarian Cancer

    SBC: THERATARGET, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): This Phase I proposal details the rationale and the research plan for the synthesis and characterization of a polymeric delivery system that will deliver two anticancer drugs with diverse mechanisms of action simultaneously into ovarian cancer cells. The delivery system will be composed of N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer as the backbone. It i ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  9. Development of an Electromyographically Controlled Electrolarynx Voice Prosthesis

    SBC: GRIFFIN LABORATORIES, INC.            Topic: NIDCD

    DESCRIPTION (provided by applicant): The most common artificial voice source for post-laryngectomy speech rehabilitation is the hand-held buzzer or electrolarynx (EL). This device is relatively easy to use and enables most laryngectomees to verbally communicate, but with reduced intelligibility and markedly degraded naturalness. In addition, EL speech is often described as robotic and monotone, at ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  10. Low-Cost, Noninvasive Liver Iron Measurements in African American Iron Overload

    SBC: Avrin, William F.            Topic: NIMHD

    DESCRIPTION (provided by applicant): This STTR program will test the utility of a low-cost device for noninvasive liver iron measurements, by using the device to determine the prevalence of iron overload in African Americans. African American iron overload is both an under-studied health issue in a medically underserved population, and an example of the wider problem of mild to moderate iron overl ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
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