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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. In-situ Gelling Protein Polymer Intravascular Embolic Agent for Hepatic Carcinoma

    SBC: THERATARGET, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): This Phase I proposal addresses the significant need for improved treatment options for patients with liver cancer, the fifth highest incidence of cance in the world. Because of the lack of symptoms, hepatocellular carcinoma (HCC) is detected at advanced stages in 84% of cases, for which the 1-year survival rate is 22% and at 5 years it is 5%. The only curativ ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  2. CDX-301 and Plerixafor Combination in Stem Cell Mobilization for Transplantation

    SBC: CELLDEX THERAPEUTICS, INC.            Topic: OD

    DESCRIPTION (provided by applicant): The overarching goal of this proposal is to evaluate a novel method to mobilize and procure a hematopoietic stem cell (HSC) allograft which we hypothesize will lead to rapid hematopoietic engraftment but cause less graft versus host disease (GVHD) compared to G-CSF mobilized peripheral blood stem cells (G-PBSC) following allogeneic HSC transplantation (HSCT). W ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  3. Hybrid DNN-based Transfer Learning and CNN-based Supervised Learning for Object Recognition in Multi-modal Infrared Imagery

    SBC: TOYON RESEARCH CORPORATION            Topic: 1

    On this effort Toyon Research Corp. and The Pennsylvania State University are developing deep learning-based algorithms for object recognition and new class discovery in look-down infrared (IR) imagery. Our approach involves the development of a hybrid classifier that exploits both transfer learning and semi-supervised paradigms in order to maintain good generalization accuracy, especially when li ...

    STTR Phase I 2018 Department of DefenseNational Geospatial-Intelligence Agency
  4. N/A

    SBC: Alliance Pharmaceutical Corp.            Topic: N/A

    N/A

    STTR Phase I 2000 Department of Health and Human ServicesNational Institutes of Health
  5. ORAL THERAPEUTICS FOR VIRAL MALIGNANCIES

    SBC: Gene Regulation Laboratories            Topic: N/A

    N/A

    STTR Phase I 1999 Department of Health and Human Services
  6. A novel recombinant vaccine against Cryptococcus.

    SBC: MYCOLOGICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Cryptococcus neoformans is an encapsulated pathogenic yeast that causes pulmonary infections and meningoencephalitis in humans and other animals. During the last 20 years, there has been a dramatic increase in the incidence of cryptococcosis throughout the world that mirrors the increase in not only HIV infections, but also in the growing number of immuno comp ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  7. Anti Inflammatory Membranes for Implantable Biosensors

    SBC: APPLIED TISSUE AND MATERIALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The prolonged inflammatory response to an implant is one of the primary causes for the failure to integrate implanted devices into tissue. The source of inflammation common to almost all implants is the foreign body response. Based on evidence in the literature and from our research team, the inflammatory response is mediated by the reactive oxygen species gene ...

    STTR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  8. Dynamical Assessment of Cerebral Autoregulation

    SBC: DYNADX CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Cerebral autoregulation that maintains perfusion in response to fluctuations of systemic blood pressure (BP) is lost post-stroke and traumatic brain injury (TBI). Noninvasive bedside methods are urgently needed to identify people with impaired autoregulation who may be at increased risk for stroke and adverse outcomes. The phase I goals are: 1) To develop and o ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  9. Tooth Phone Auditory Device TPAD

    SBC: Audiodontics LLC            Topic: N/A

    DESCRIPTION (provided by applicant): TOPIC - Tooth Phone(R) Auditory Device - TPAD ABSTRACT The Tooth Phone(R) Auditory Device - TPAD is new alternative device to the only direct bone conduction hearing aid currently accepted by the Food and Drug Administration (FDA) for the treatment of certain specific types of hearing loss. Unlike the precedent FDA approved device that uses an osseointegrated i ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  10. Behavioral Technology for Teaching Symbolic Relations

    SBC: PRAXIS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This application seeks support for an STTR Phase I project to develop and study a computer-based product intended primarily for teaching children with intellectual disabilities. The product addresses a pivotal skill - symbolic matching to sample -- which is a target of many current programs for teaching this population. In a symbolic matching task, students are ...

    STTR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
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