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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Preparation of a Quantitative Apoptosis Imaging Agent

    SBC: NAVISCAN PET SYSTEMS, INC.            Topic: N/A

    This proposal addresses development of new imaging technology for noninvasive quantitative measurement of apoptosis in vivo. Apoptosis is genetically defined cell death. Understanding the role of apoptosis is critical to the development of new molecular-based therapeutic modalities. An apoptosis-imaging agent could be used to modify therapy for cancer patients, and to monitor cardiac transplant pa ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  2. Hypocretins and Their Role in the Control of Sleep

    SBC: Neurocrine Biosciences, Inc.            Topic: N/A

    DESRIPTION: (Adapted from the Applicant?s Abstract) Insomnia is one of the more prevalent sleep disorders in the US, affecting about 10 percent of the population. Other sleep disorders include obstructive sleep apnea, restless leg syndrome and narcolepsy. Recently, a mutation in the G-protein coupled receptor hypocretin receptor-2 has been linked to the development of narcolepsy in dogs. In additi ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  3. Compact Tunable Mid-IR/UV Laser/Ion source for IR MALDI

    SBC: OPOTEK, INC.            Topic: N/A

    The goal of this Phase II STTR cooperative research program between OPOTEK and Emory University is to continue development of a small and inexpensive infrared laser based on optical parametric oscillator (OPO) technology and to develop a target system specifically designed for liquid matrix IR-MALDI. This package of IR laser and ion source is designed for high-end MALDI mass spectrometers, and wil ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  4. Compact Tunable Mid-IR/UV Laser/Ion source for IR MALDI

    SBC: OPOTEK, INC.            Topic: N/A

    The goal of this Phase II STTR cooperative research program between OPOTEK and Emory University is to continue development of a small and inexpensive infrared laser based on optical parametric oscillator (OPO) technology and to develop a target system specifically designed for liquid matrix IR-MALDI. This package of IR laser and ion source is designed for high-end MALDI mass spectrometers, and wil ...

    STTR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  5. TREATMENT OF OVARIAN CANCER WITH CONTORTROSTATIN

    SBC: PIVOTAL BIOSCIENCES            Topic: N/A

    DESCRIPTION: (Applicant's Description) Ovarian carcinoma (OC) is the fourth most frequent form of cancer death of women in the United States. Approximately 1 in 70 women in the US will develop OC; in advanced stages of the disease there is a 5-year survival of about 15-20%. Present methods of treatment for advanced sta ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  6. Icon Teacher: Stimulus Control Shaping Technology

    SBC: PRAXIS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We request Phase I funding to support development of a prototype product, Icon Teacher, that is intended for certain children who require augmentative/ alternative communication (AAC) intervention. In AAC systems, children who have not learned to speak may indicate wants and needs by responding nonverbally to symbol ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  7. BEHAVIORAL TECHNOLOGY FOR INSTRUCTIONAL READINESS

    SBC: PRAXIS, INC.            Topic: N/A

    This application seeks support for an STTR Phase I project to develop and study a computer software product for computer-managed evaluation and instruction with children who have severe mental retardation, autism, and other intellectual disabilities. The product is primarily targeted to those students who lack the behavioral prerequisites to participate in ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  8. Development of basic tools for Cancer Research

    SBC: PROTEIN RESEARCH, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Our goal is to produce active recombinant proteins involved in cancer progression and other important cellular processes. Recombinant proteins in biomedical research have now become an essential tool to study many aspects of cellular biology. Genes coding for several important cellular function such as tumor suppres ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  9. Human Protein Kinase Microarrays

    SBC: PROTOMETRIX            Topic: N/A

    DESCRIPTION (provided by applicant): The analysis of protein function has conventionally been done by studying, in depth, a single protein. Recently several groups have initiated efforts to display proteins in two-dimensional array suitable for performing various types of binding studies or assays. In particular, Dr. Snyder's laboratory has developed a microwel ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  10. Control of Biofilms by Natural Products

    SBC: SEQUOIA SCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The importance of Biofilms in chronic and treatment-resistant infectious disease, increasingly is clear. Biofilms also are a major problem in industrial processes. The focus of this proposal is to develop methods for discovering compounds that block and/or reverse biofilm formation, and to discover, and structurally characterize, a ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
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