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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 1541 - 1550 of 1616 results
 
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  • Record 1001 TO 1616

  1. Modification of Intervertebral Disk Fatigue Resistance

    SBC: Ampac Biotechnology, Inc.            Topic: N/A

    DESCRIPTION (Provided by Applicant): An investigation is proposed exploring the use of biochemical reagents to improve fatigue resistance of intervertebral disc tissue. While not well quantified, the capacity of spinal tissue to withstand repetitive loading is a critically important factor in the progression of spinal osteoarthritis. Current treatments for ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health

  2. FLUOROPHORE GLYCOSYLATION PROFILES--PROSTATE CANCER TEST

    SBC: Glyko, Inc.            Topic: N/A

    N/A

    STTR Phase I 1998 Department of Health and Human Services

  3. Development of a Multi-sample Solids NMR Probe

    SBC: REVOLUTION NMR LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this application is to enable more efficient and cost-effective utilization of solid state NMR systems for health care research. Solid-state NMR spectroscopy is an important tool for the analysis of Pharmaceuticals and biological compounds such as proteins, but is often not used due to the length of time required to collect data. The specific a ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health

  4. HIGH THROUGHPUT GENOTYPING TECHNOLOGY

    SBC: PARALLELE BIOSCIENCE, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): There is a need for inexpensive high throughput platforms for analyzing large number of single nucleotide polymorphisms. In this proposal, we describe the development of a technique, which will enable more than 10,000 SNPs to be analyzed in a single tube and its transfer to a commercial entity (ParAllele Genomcis Inc.). T ...

    STTR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health

  5. Preclinical development of the tsetse thrombin inhibitor

    SBC: L2 DIAGNOSTICS LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Thromboembolic disease is a major cause of morbidity and mortality in the developed world. Despite the need for effective therapies for treating and preventing pathologic activation of thrombosis, there are relatively few currently available alternatives to intravenous heparin. The total commercial market for antithrombotic agents has been estimated at 2 billio ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health

  6. Novel Therapy for Asthma Targeting beta-Adrenoceptors

    SBC: INVERSEON, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Asthma is a chronic inflammatory disease that effects approximately 17 million Americans. Despite the availability of inhaled beta-adrenoceptor (betaAR) agonists and corticosteroids, 1.8 million emergency room visits a year occur due to severe asthma attacks demonstrating a significant unmet medical need. The Company intends to develop and commercialize INV102, ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health

  7. Combo beta-blockers & beta2-agonists for asthma therapy

    SBC: INVERSEON, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Approximately 5% of Americans have asthma, an inflammatory airway disease whose hallmark is airway hyper-reactivity (AHR). During AHR, bronchial smooth muscles rapidly constrict resulting in airway obstruction. Most patients self-administer inhaled beta2-adrenoceptor (beta2AR) agonists such as salmeterol for relief of this life-threatening event. Unfortunately, ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health

  8. High-throughput portable software for fragment-based drug design

    SBC: ACPHARIS            Topic: NIGMS

    DESCRIPTION (provided by applicant): Fragment-based drug design (FBDD) is a combinatorial approach in which individual fragments binding to regions of the target site are selected from a fragment library, and then combined to form potential lead compounds.Interest in this approach has significantly increased during the last few years, with many companies using FBDD methods based on X-ray crystallo ...

    STTR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health

  9. Remote focusing through spatial light modulation for multifocal multiphoton micro

    SBC: BOULDER NONLINEAR SYSTEMS, INC.            Topic: NIMH

    DESCRIPTION (provided by applicant): Nonlinear optical microscopy techniques (such as two-photon florescence) are being used to acquire volumetric (i.e. three dimensional) images that probe several hundred microns into scattering tissue. These techniques are being combined with fast acquisition schemes to allow imaging of live, moving specimens at high NA. This combination allows for high-resoluti ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health

  10. REMOTE EXPERT SCREENING FOR DIABETIC RETINOPATHY

    SBC: EYETEL CORPORATION            Topic: N/A

    N/A

    STTR Phase I 1999 Department of Health and Human Services
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