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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Modified HER-2 Tumor Antigens for Vaccination in Cancer

    SBC: L2 DIAGNOSTICS LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Breast cancer remains one of the most insidious and difficult to treat human malignancies, affecting thousands of individuals each year. Our proposed studies are aimed at developing a novel tumor immunotherapy by using cryptic peptides of Her-2 protein and modified Her-2 peptides, both of which break immune tolerance to ?self? tumor antigens expressed on breast ...

    STTR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  2. Development of breakthrough intra-operative detector and imaging system for parat

    SBC: Anasys Instruments Corp.            Topic: 102

    DESCRIPTION provided by applicant There are parathyroid glands in the neck and they are responsible for the production of parathyroid hormone which maintains calcium homeostasis throughout the body They are difficult to identify relative to the other tissues in the neck such s lymph nodes fat thyroid etc This has resulted in the incidence of accidental parathyroid removal ranging from ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. DNA helicase and primase inhibitors for biodefense

    SBC: MICROBIOTIX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term goal of this project is to identify specific inhibitors of B. anthracis helicase and primase and develop them into novel antibiotics for bio-defense. New antibiotics based on novel chemical scaffolds are vital to the bio-defense armory because they are likely to be effective against both natural and engineered resistant forms of bio-terrorist agen ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  4. Feelix @ Home: Testing and optimization of a smart stethoscope for home use to monitor changes in lung status of individuals with chronic conditions

    SBC: SONAVI LABS INC            Topic: NHLBI

    Project SummaryThe goal of this project is to further develop an existing smart stethoscope in order to be capable of monitoring pediatric patients at home who suffer from asthma as well as adults with COPD. Lung diseases impose a serious burden on healthcare systems, individuals and governments. The World Health Organization (WHO) found that chronic obstructive pulmonary disease (COPD) and lower ...

    STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  5. Broncho-adventitial Drug Delivery: Paclitaxel for Bronchial Carcinoma

    SBC: MERCATOR MEDSYSTEMS, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Over 215,000 people will be diagnosed in 2008 with bronchial carcinoma in the U.S. according to the Surveillance, Epidemiology, and End Results (SEER) Program of the National Cancer Institute. Currently, asthma afflicts22.9 million people in the U.S., and tracheomalacia is believed to afflict 3 million people in the U.S. In addition to these chronic or deadly c ...

    STTR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  6. Development of a Clinical Screening Platform for Type 1 Diabetes

    SBC: Op-T-Mune, Inc            Topic: NIDDK

    AbstractA major shortfall in clinical care for diabetes is a rapid and accurate screen for progression to diseaseCurrent criteria involve HLA haplotypeand the presence of auto antibodiesAAGenome wide associated studiesGWASrevealed only immune associated genes including HLA as T D predictorsThe ability to differentiate from other diseases was very limitedPre typediabetesp T Dis now being identified ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Control of Biofilms by Natural Products

    SBC: SEQUOIA SCIENCES, INC.            Topic: N/A

    N/A

    STTR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  8. Phase II STTR: Portable Device for Telecare Monitoring of Elderly People

    SBC: BIOSENSICS LLC            Topic: NIA

    DESCRIPTION (provided by applicant): We propose to address two important public health quality of life concerns - fall prevention and frailty in older adults by developing an accurate wearable sensor technology that more accurately characterizes physical activity, risk of falling and early indicators of frailty. In Phase I of this STTR project, we developed a unique platform (PAMSysTM: Physical Ac ...

    STTR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  9. Single Cell Analysis via Nanoscale Tip Enhanced Laser Ablation Mass Spectrometry

    SBC: Anasys Instruments Corp.            Topic: NIGMS

    DESCRIPTION provided by applicant The goal of the proposed Phase II STTR research is to develop an imaging system capable of detecting and identifying biomolecules in cells and tissue sections with sub cellular spatial resolution The system combines an atomic force microscope AFM with mass spectrometry MS analysis and utilizes a unique tip enhanced laser ablation TELA method developed in ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Automated Analysis of Skeletal Muscle Fiber Cross-sectional Area and Metabolic Ty

    SBC: VALA SCIENCES, INC.            Topic: NIAMS

    DESCRIPTION (provided by applicant): The accurate quantification of skeletal muscle morphology is desired in a wide variety of medical areas such as muscle regeneration, muscular dystrophy, exercise physiology, and nutrition. For such studies, skeletal muscle is often fixed, sectioned, and labeled to visualize the borders of the muscle fibers, and digitally photographed. Investigators then use lab ...

    STTR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
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