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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Breakthrough intra-operative detection of the parathyroid glands

    SBC: Anasys Instruments Corp.            Topic: NIBIB

    DESCRIPTION (provided by applicant): Currently, about 20 million Americans have some form of thyroid disease. Thyroid disease occurs when the thyroid gland does not supply the appropriate amount of thyroid hormone needed. Thyroid and parathyroid diseases combine the fields of endocrinology and oncology leading to a complex combination of pathological conditions. When the disease cannot be treated ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  2. Phase 1 Safety and Pharmacokinetics of ALK001 in people over 60

    SBC: ALKEUS PHARMACEUTICALS, INC.            Topic: NEI

    DESCRIPTION (provided by applicant): The overall goal of this collaborative research between Alkeus Pharmaceuticals and Columbia University Medical Center is to evaluate a new oral investigational treatment for dry age-related macular degeneration (dry-AMD), the leading cause of blindness in the U.S., and Stargardt's disease, also known as juvenile macular degeneration. The investigational co ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  3. ShH10-Mediated Long-Term Delivery of Neurotrophic Factors in Animal Models of Gla

    SBC: AVALANCHE BIOTECHNOLOGIES, INC.            Topic: NEI

    DESCRIPTION (provided by applicant): The objective of this proposal is to examine the efficacy of a novel adeno-associated virus (AAV) variant, ShH10, expressing neurotrophic factors for the treatment of glaucoma. Glaucoma is the second leading cause of blindness with high associated societal costs, and is expected to grow. The hallmark of glaucoma is retinal ganglion cell (RGC) death, which leads ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  4. Development of a new Imaging Platform for Pharmaceutical and Biomedical applicati

    SBC: Anasys Instruments Corp.            Topic: NIGMS

    DESCRIPTION (provided by applicant): In this project, the breakthrough new technique of nanoscale infrared (IR) spectroscopy, pioneered by Anasys Instruments, will be adapted and refined for Pharmaceutical and biological systems. The technique has numerousapplications such as Polymorph screening; sub-cellular spectroscopy and Drug-Polymer composites. In this research proposal, we will focus on dem ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  5. GPU Accelerated Protein Docking Software with Flexible Refinement

    SBC: ACPHARIS            Topic: NIGMS

    DESCRIPTION (provided by applicant): Protein-protein interactions are involved at multiple points in virtually all biological pathways. Understanding such interactions is also important for the design of biologics that can target extracellular receptors with high affinity and specificity. Since determining the structure of protein complexes by X-ray crystallography is expensive and slow, it is im ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  6. Development of website devoted to legal issues associated with medical research

    SBC: IP ADVANTAGE            Topic: NIGMS

    DESCRIPTION (provided by applicant): There is a clear lack of needed information geared towards investigators and other clinical trial professionals on the legal/regulatory aspects of clinical trials. While keeping up with regulatory changes related to clinical trials is challenging staying abreast of other areas of the law which do not immediately come to mind when thinking about clinical trials ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  7. Protein Sequencing Tools for Biological Therapeutics

    SBC: PROTEIN METRICS INC            Topic: NIGMS

    DESCRIPTION (provided by applicant): Mass spectrometry has become a method of choice for identifying and characterizing small quantities of proteins in complex mixtures. However, the ability to perform the identification in a high- throughput fashion hasdepended on the availabilit of protein sequence databases. This means that proteins from organisms with unsequenced genomes (e.g. peptide toxins) ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  8. Discerning Pathological and Braxton Hicks Contractions in Mid-Trimester Gestation

    SBC: CERVOCHECK, LLC            Topic: NICHD

    DESCRIPTION (provided by applicant): This STTR Phase I Project will determine if uterine activity measured from the utero-cervico- vaginal wall can be a predictor for discerning Braxton Hicks (false) contractions and pathological (true) labor contractionsin mid-gestation pregnancies. We will use a previously developed prototype to measure uterine activity from the utero-cervico-vaginal interface t ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  9. Non-invasive neonatal respiration monitor

    SBC: FLUOROMETRIX CORPORATION            Topic: NICHD

    DESCRIPTION (provided by applicant): Preterm birth requires technologies for supporting immature organ systems on one hand while minimizing technology-induced injury on the other that may contribute to long-term adverse outcomes. Specific problems of thiskind are extremes in arterial partial pressure of oxygen and carbon dioxide. A variety of pathological conditions are known to result from both ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  10. Developing an online educational curriculum to enhance parent-supervised driving

    SBC: Parallel Consulting, LLC            Topic: NICHD

    DESCRIPTION (provided by applicant): Motor vehicle crashes are the leading cause of death and injury for teens, accounting annually for over 3000 deaths, 100 times as many injuries, and over 14 billion dollars in associated costs. The CDC has identified traffic crashes and associated injuries as a top public health priority. Inexperience is the leading cause of crashes among novice teen drivers, b ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
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