You are here

Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Biomarker-enhanced Artificial Intelligence-Based Pediatric Sepsis Screening Tool Towards Early Recognition and Personalized Therapeutics

    SBC: COMPUTER TECHNOLOGY ASSOCIATES, INC.            Topic: NIAID

    PROJECT SUMMARY The overall objective of this proposed STTR effort is focused on the derivation and validation of a commercialized biomarker-enhanced artificial intelligence (AI)-based pediatric sepsis screening tool (PSCT) that can be incorporated into emergency department (ED) workflows to enhance early recognition and the initiation of timely, aggressive personalized sepsis therapy. The early r ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  2. New Agents for the Treatment on Mycobacteria Avium Infections

    SBC: Quercus Molecular Design, LLC            Topic: NIAID

    Abstract: Non-Tuberculosis Mycobacteria (NTM) are responsible for widespread, life threatening infections of the lungs, skin, lymphatic and hematological systems. The rapid, global spread of resistant organisms has significantly reduced the number of agents that can be used effectively to treat these infections. Of specific clinical relevance are the slow-growing Mycobacterium avium complex (MAC) ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  3. A digital tool for monitoring speech decline in ALS

    SBC: MODALITY.AI , INC            Topic: NIDCD

    PROJECT SUMMARYAmyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease resulting in the progressive loss of limb, trunk, and head and neck (bulbar) motor function and is the most common adult-onset motor neuron disease. The disease is characterized by significant across-patient heterogeneity in the onset region and in pattern and progression rate, making early and accurate diagnos ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  4. Discovery of Bunyaviral Endonuclease Inhibitors for Antiviral Therapy

    SBC: MICROBIOTIX, INC.            Topic: NIAID

    Abstract Segmented negative-sense, single-stranded RNA viruses (sNSVs), which include bunyaviruses, are causative agents of human diseases. Rift Valley Fever Virus (RVFV), a bunyavirus, causes hemorrhagic fever in humans with a case fatality rate of patients developing hemorrhagic fever reaching approximately 50% and has been classified by the NIAID as a Category A Priority Pathogen. RVFV is mosqu ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  5. Development of Broad-Spectrum CyclicAmphiphilic Peptides against Multidrug-Resistant Bacteria

    SBC: AJK BIOPHARMACEUTICAL LLC            Topic: NIAID

    ABSTRACT The emergence of antibacterial resistance to common frontline antibiotics, such as methicillin, vancomycin, cephalosporins, and carbapenem, have created a global public health challenge for millions of patients. It is therefore critical to discover and commercialize new antimicrobial agents that can successfully neutralize multidrug-resistant bacteria (MDRB) with minimal toxicity. The obj ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  6. Computer-based Learning to Enhance ADRD Care in Prison: Just Care for Dementia

    SBC: KLEIN BUENDEL, INC.            Topic: R

    Project Summary/Abstract U.S. prison systems face sharply increased demands in caring for older people living in prisons. Alzheimerandapos;s Disease and related dementias (ADRD) are age-related diseases. Prison populations are over- represented by minority populations who experience disparities in prevalence and incidence of dementia. Prison health, social, and security staff perceive they lack th ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  7. Development and characterization of HIV-1 Tat degraders

    SBC: Thimble Therapeutics Inc            Topic: NIAID

    AbstractDespite effective antiretroviral therapy (ART), latent proviruses can reinitiate viral production upon cell stimulation or treatment interruption. The viral Tat protein enhances transcript elongation from the HIV-1 promoter, controlling the switch between latency and active viral production. The block-and-lock functional cure aims at the transcriptional silencing of the viral reservoir, re ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  8. Nanoimmunotherapy for chronic immune-mediated diseases

    SBC: GENERAL NANOTHERAPEUTICS LLC            Topic: NIAID

    ABSTRACT Current pharmaceutical agents that are used for the treatment of immune-mediated inflammatory conditions including autoimmune diseases generally do not lead to remission and frequently carry toxic side effects. Here we propose a strategy that can harness the capacity of the immune system to induce immunoregulatory response that can suppress immune hyperactivity and chronic inflammation in ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  9. Next generation anti-cancer drugdelivering cement for bone metastasis patients

    SBC: CURER INC            Topic: 102

    Abstract Our mission is to develop an innovative anti-cancer drug delivering bone cement for bone metastasis patients, which can be injected into metastasis-caused bone degeneration sites in a minimally invasive manner, to regress cancer, regenerate bone, and stop the pain. Metastasis is the main cause of cancer death. Bone is one of the most frequent cancer metastatic sites. About 350,000 America ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  10. A web-based platform to support team-based genome diagnostics

    SBC: FRAMESHIFT LABS INC            Topic: 172

    Summary/Abstract Genomic sequencing is rapidly becoming a standard tool in diagnosing complex diagnostic cases, especially in critically ill newborns, and patients suffering from rare diseases. Current programs focused on addressing these cases utilise a team-based approach to identify, interpret and evaluate a patient’s genetic variants. These diverse teams include bioinformaticians, medical ge ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
US Flag An Official Website of the United States Government