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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. High Efficiency Microfluidic Purification of Stem Cells to Improve Transplants

    SBC: GPB Scientific, Inc.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Hematopoietic stem-progenitor cell (HSPC) transplantation is an established therapy for many malignant and non-malignant diseases. HSPCs are harvested clinically from 3 sources: G-CSF mobilized adult peripheral blood (PBSC), bone marrow (BM), and umbilical cord blood (UCB). Because erythrocytes increase both the risk of harmful side effects in transplant patien ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  2. ECG Device for LQTS Screening in Newborn

    SBC: PULSENTRY, INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Long QT syndrome (LQTS) occurs in 1 out of 2,500 infants, accounts for 10-15% of deaths due to sudden infant death syndrome (SIDS), and is a major cause of mortality and morbidity in infants, children, and young adults.Electrocardiograms (ECGs) can detect LQTS at a pre-symptomatic stage, and treatments are available to prevent cardiac events and death. ECGs hav ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  3. ASC101 Enhancement of Regenerative Capacity of Amniotic Fluid-derived Stem Cells

    SBC: TARGAZYME, INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): In the present STTR we propose to investigate two novel approaches in our exploration of the therapeutic and regenerative potential of cell-based medicine. Furthermore, we will utilize a preclinical animal model of compression syndrome (CS) that mimics the pathophysiology of multiple injuries such as crush injuries, burns, circulation blockage, fractures, hemor ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  4. Ventilation Stethoscope using Hyperpolarized Xenon

    SBC: MIRTECH INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Ventilator Induced Lung Injury (VILI) is a common cause of morbidity and sometimes mortality in critically ill patients with respiratory failure. The types of VILI include barotraumas, volutrauma, atelectrauma, and biotrauma. Thus ventilator setting is a delicate balance between achieving sufficient ventilation but avoiding excessive pressure and overdistensio ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  5. COA360H: A Tool to Assess Accreditation of Healthcare Organizations

    SBC: DayStar Research            Topic: NIMHD

    DESCRIPTION (provided by applicant): This Phase I STTR application seeks support for research to enhance the commercial viability of a tool to assess the cultural competence of health care organizations. The Cultural-competency Organizational Assessment - 360 (COA360) is a web-based tool to measure the cultural competence of healthcare organizations. Major changes in the regulatory environment ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  6. A novel 3D microscope for imaging and photostimulation

    SBC: BOULDER NONLINEAR SYSTEMS, INC.            Topic: NIMH

    DESCRIPTION (provided by applicant): Mental disease, including schizophrenia, depression and autism spectrum disorders, are still poorly understood, although it is clear that they mostly represent cortical disorders. The cortex is the primary site of higher mental functions, and despite extensive research, there is still no unified theory of how the cortex works. This is partl due to the fact that ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  7. Automated image-based biomarker computation tools for diabetic retinopathy

    SBC: EYENUK, INC.            Topic: NCATS

    DESCRIPTION (provided by applicant): In this STTR project, we present EyeMark, a set of tools for automated computation of biomarkers for diabetic retinopathy using retinal image photographs. Specifically, we will develop tools for computation of microaneurysm (MA) appearance and disappearance rates (jointly known as turnover rates) for use as a biomarker in monitoring progression of diabetic reti ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  8. Human monoclonal antibodies for prevention of S. aureus infections

    SBC: SORRENTO THERAPEUTICS, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Using mouse monoclonal antibodies (mAbs) raised against the mediators of quorum sensing (QS), the Auto-Inducing Peptides (AIPs), researchers at The Scripps Research Institute (TSRI) have demonstrated that S. aureus infections can be prevented in animal challenge models. This approach, known as quorum quenching (QQ) is unique in at least two significant ways: fi ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  9. Investigation of a nanoparticle albumin-bound mTOR inhibitor, nab-rapamycin for t

    SBC: AADI, LLC            Topic: NCI

    DESCRIPTION (provided by applicant): In 2011, it is estimated that there will be 69,250 new bladder cancer cases in the United States, resulting in 14,990 deaths. Most cases (70-80%) present with nonmuscle-invasive bladder cancer (NMIBC) [1, 2]. Intravesical bacillus Calmette-Guerin (BCG), which elicits a nonspecific local immune response, is considered the standard first-line treatment. However, ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  10. Optogenetic Multiparametric Assay for HT Cardiotoxicity Testing

    SBC: VALA SCIENCES, INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Monitoring physiology of individual cardiomyocytes in high throughput has not been reported. The inability to perform high throughput physiological measurements limits many basic and applied studies, including the use of stem cell derived cardiomycoytes in cardiotoxicity testing. Current automated cardiotoxicity tests have poor predictive value because they use ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
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