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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Nano-Ceramic for Metabolic Stem Cell Engineering

    SBC: Angstrom Medica, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall objective of this project is to develop a clinically and commercially viable tissue engineered bone construct using nanocrystalline ceramic scaffolds for proliferating and differentiating adipose-derived progenitor cells into cells of the osteogenic lineage. The use of a nanostructured hydroxyapatite (nano-HAP) scaffold offers several advantages for ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  2. METHOD FOR DISCOVERING NOVEL TRANSCRIPTIONAL REGULATORS

    SBC: CROSSLINK GENETICS CORPORATION            Topic: N/A

    N/A

    STTR Phase I 1998 Department of Health and Human Services
  3. Mapping disease-specific human protein networks

    SBC: Curagen Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): While the human genome sequence is known, medical advances will require knowledge of how individual genes and proteins assemble into functional biological networks. These networks are built in part through physical interactions between proteins. Protein interaction networks can now be probed using highthroughput experimental methods, yet challenges remain: dat ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  4. Behavioral Multimedia for ACL Reconstructive Surgery

    SBC: VIRTUAL BRANDS            Topic: N/A

    DESCRIPTION (provided by applicant): Approximately 80,000 Americans sustain acute tears of the anterior cruciate ligament (ACL) of the knee each year, with associated healthcare costs estimated at roughly 1 billion dollars annually. Surgical reconstruction followed by an extended rehabilitation period is commonly recommended for ACL tears. The purpose of this STTR project is to develop a compreh ...

    STTR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  5. Multimedia for College Student Eating Disorder Education

    SBC: VIRTUAL BRANDS            Topic: N/A

    DESCRIPTION (provided by applicant): Eating disorders and sub-clinical eating disturbances are widespread among female college students. Unfortunately, many college students with disordered eating fail to seek help due to embarrassment and privacy concerns. The purpose of this STTR project is to develop an interactive CD-ROM to educate college students about essential eating disorder issues. Using ...

    STTR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  6. Multimedia for Exercise During Pregnancy and Postpartum

    SBC: VIRTUAL BRANDS            Topic: N/A

    DESCRIPTION (provided by applicant): Women's exercise is significantly reduced during pregnancy and postpartum due to the physical and psychological demands of childbearing. For example, about 60 percent of pregnant women are sedentary, which is significantly above the national average of 25 percent for U.S. adults. Thus, pregnancy and postpartum are strong contributors to either a sedentary or a ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  7. Investigation of Shape Memory Polymers in Orthodontics

    SBC: New Ortho Polymers            Topic: N/A

    DESCRIPTION (provided by applicant): All orthodontic treatment is based on the application of optimal forces that minutely displace teeth initiating a biological response that alters both hard and soft tissues. Because of the precision of control, most treatment is carried out with fixed appliances that are capable of delivering forces and moments to the crowns of teeth. More limited treatment an ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  8. Parametric models for survival analysis

    SBC: EPICENTER SOFTWARE            Topic: N/A

    DESCRIPTION (provided by applicant): The most commonly used statistical methods for the design and analysis of cancer clinical trials today rely heavily on the idea of proportional hazards or its generalizations; i.e., that the important differences between treatments are reflected in the differences between failure rates. Implicit in the use of these methods is the assumptio ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  9. Novel Bone Graft Material With Osteoinductive and Hemostatic Function

    SBC: CEREMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Bone is one of the most implanted materials in the body, second only to blood. The market for bone grafting and dental implants is currently over 4.8 billion and is expected to grow rapidly in the future. Autograft has traditionally been used, but limited supply, donor-site risks, and cost created a demand for bone graft substitutes. As an osteoinductive bone ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  10. Structure guided rational engineering of novel DNA reagents.

    SBC: NEW ENGLAND BIOLABS, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Type II restriction enzymes (REases) are indispensible tools of modern medical research. It has long been a goal of REase manufacturers to be able to offer programmable specificity enzymes, where the sequence recognizedand resulting cutting activity can be precisely directed to any desired point in a DNA, as this will offer opportunity for improvement in many a ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
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