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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Thiol-Reactive Crosslinkers for Biomaterials

    SBC: RECOGNITION ROBOTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): A limited number of cytocompatible crosslinkers are available for the preparation of cell-seeded hydrogels and in vivo biocompatible injectable biomaterials. To expand this selection, Sentrx Surgical, Inc. will synthesize and evaluate a series of thiol-reactive bivalent and polyvalent crosslinkers based on polyethylene glycol (PEG). We will determine the relati ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  2. Thromboresistant vascular grafts:heparin-peptidomimetics

    SBC: BIOSURFACE ENGINEERING TECHNOLOGIES            Topic: N/A

    Thrombosis of synthetic vascular grafts is a major problem with current grafts that necessitates prophylaxis, can lead to loss of patency with an attendant need for repeat surgery, and comes with a high risk of limb loss. The applicant proposes to develop thromboresistant extended polytetrafluoroethylene (ePTFE) vascular grafts that use an absorbed coating of heparin to control acute and subacute ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  3. Tick Midgut Thrombin Inhibitor as a Vaccine Target

    SBC: L2 DIAGNOSTICS LLC            Topic: N/A

    DESCRIPTION (provided by applicant): We seek in this proposal to develop a tick vaccine to block tick feeding and pathogen transmission to the vertebrate host. Ticks can harbor bacterial, viral and protozoan pathogens and infected ticks transmit pathogens to the mammalian host during feeding, causing human and cattle disease worldwide. Ixodid ticks are obligate hematophagous arthropods that feed ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  4. TITLE OMITTED

    SBC: APOLLO LIGHT SYSTEMS, INC.            Topic: N/A

    N/A

    STTR Phase I 1998 Department of Health and Human Services
  5. TLR5 Antagonists for Infectious Disease Therapy

    SBC: MICROBIOTIX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): A family of conserved toll-like receptors (TLRs) found on a variety of human cell types plays an important role in recognition of invading pathogens and in mounting an effective inflammatory immune response. Each these receptors binds a specific microbial ligand and triggers a signal transduction pathway leading to transcription of genes encoding pro-inflammato ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  6. Tooth Phone Auditory Device TPAD

    SBC: Audiodontics LLC            Topic: N/A

    DESCRIPTION (provided by applicant): TOPIC - Tooth Phone(R) Auditory Device - TPAD ABSTRACT The Tooth Phone(R) Auditory Device - TPAD is new alternative device to the only direct bone conduction hearing aid currently accepted by the Food and Drug Administration (FDA) for the treatment of certain specific types of hearing loss. Unlike the precedent FDA approved device that uses an osseointegrated i ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  7. Topical application of heterologous protein-expressing Staphylococcus epidermidis for potential therapeutic treatment of skin diseases

    SBC: Azitra Inc.            Topic: NIAID

    PROJECT SUMMARY Current treatment options for a number of skin diseases generally aim for symptomatic relief and fail to address underlying pathophysiological changes leading to skin disease In the case of genetic mutations that cause loss of function mutations supplementation of the missing protein is a viable approach to treatment However delivery of functional protein to the target keratino ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Topical Therapeutic to Promote Healing of Chronic Wounds

    SBC: Phoenicia Biosciences, Inc.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Chronic refractory, or non-healing, wounds or ulcerations of the extremities represent a major medical condition affecting millions of patients. A chronic wound is defined as a wound that does not show signs of significant healing, or progresses, after use of topical/surgical treatment measures for six months. Non-healing wounds affect 6.5 million patients, aff ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  9. TOWAR: a comprehensive Training on Women's Addiction and Recovery

    SBC: SOCIAL SOLUTIONS INTERNATIONAL            Topic: N/A

    DESCRIPTION (provided by applicant): The purpose of this Phase I Small Business Technology Transfer (STTR) proposal is to develop a woman-focused model of care specifically for use in a drug court system. Social Solutions International, Inc. (SSi), in cooperation with UCLA Integrated Substance Abuse Programs (ISAP), proposes to develop this woman-focused, innovative model of a drug court program. ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  10. Toward Automated Spike Sorting via Ground Truth Neural Recordings

    SBC: Leaflabs, LLC            Topic: 101

    PROJECTSUMMARY Scaling extracellular electrophysiology to higher channel counts is hindered by the burden of data handling storageand especially preprocessinge gspike sortingThe burden of spike sorting can in principle be reduced through a combination of high density multielectrode arrayprobetechnology and algorithm optimization to yield a spike sorting method that is both highly accurate and full ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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