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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Improved Performance of Neonatal Vascular Access Catheters via 3D Magnetic Printing

    SBC: N2 Biomedical, LLC            Topic: NICHD

    DESCRIPTION provided by applicant Clinical treatment of infants in the neonatal intensive care unit NICU is particularly challenging due to their small anatomies medical instability and immature physiological processes Treatment is often complicated by the lack of therapeutic devices and instrumentation designed specifically to accommodate this unique patient population For instance curr ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Macromolecule Crystallization Screening Results Analysis

    SBC: iXpressGenes, Inc.            Topic: 100

    DESCRIPTION provided by applicant Crystallization followed by subsequent structure determination is a major step in understanding the structure function relationship of macromolecules Understanding macromolecule structure has become a key part in the development of new pharmaceuticals and is a major area of NIH research Crystallization however is also the rate limiting step despite techno ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. BlueBox- a complete code blue data recorder

    SBC: NeoVative, Inc.            Topic: 400

    DESCRIPTION provided by applicant andquot Code blue andquot the term used in hospitals to call for an immediate cardiopulmonary resuscitation CPR signals dire emergencies where medical errors can occur and lives can be lost Reviewing CPR performance of the code blue team is a cornerstone for improving outcomes Thorough and accurate recording of code blue events enable detailed reviews to ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Developing efficient and safe cell-permeable reprogramming peptides for generation of iPS cells.

    SBC: Vivoscript, Inc.            Topic: 200

    DESCRIPTION provided by applicant The groundbreaking discovery of induced pluripotent stem cells iPSCs has opened a new page for developing personalized cell based therapies against various devastating human diseases without ethical concerns of using human embryonic stem cells However the future clinical applications of iPSCs remain in doubt due to potential risks of undesired genomic alter ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Mechanistic Studies of a Novel Small Molecule HIV Inhibitor

    SBC: ADVANCED GENETIC SYSTEMS, INC.            Topic: 100

    DESCRIPTION provided by applicant There is a significant need for novel HIV therapies given the emergence of viruses resistant to existing drug regimens The Rev RRE protein RNA interaction in HIV plays an essential role in the transport of viral mRNA from the nucleus to the cytoplasm where it can be translated or packaged Previously we identified the thienopyridine scaffold that inhibited HIV ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  6. Optimizing HaploSeq for whole-genome phased haplotypes in biomedical applications

    SBC: ARIMA GENOMICS, INC.            Topic: 172

    DESCRIPTION provided by applicant Phenomenal advances in DNA sequencing technologies have enabled systematic identification of genetic variants in human individuals and the recent FDA marketing authorization of the first next generation genome sequencer signals the arrival of a new era of pharmacogenomics and personalized medicine Nevertheless DNA sequencing alone fails to provide complete i ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Targeting C/EBP-beta Phosphorylation for the Treatment of Lung Fibrosis

    SBC: XFIBRA, LLC            Topic: NHLBI

    DESCRIPTION provided by applicant Activation of lung myofibroblasts LMF is responsible for the development of lung fibrosis in chronic lung diseases of all causes and remarkably LMF clearance by apoptosis may prevent development of lung fibrosis and lung injury and possibly allow recovery from reversal of lung fibrosis There is full agreement among tissue fibrosis experts that inhibiting o ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Utilization of cord blood-expanded stem cells for megakaryocyte and platelet production

    SBC: AllCells, LLC            Topic: NHLBI

    DESCRIPTION provided by applicant Platelet transfusions are the most effective treatments for patients with thrombocytopenia The growing demand for platelet transfusions is often limited by shortage in the platelets PTL supply due to dependency on volunteer donors short shelf life risk of infections and alloimmunization It is therefore critical to create an efficient donor independent ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Continuing Care App for Probationers and Parolees with Substance Use Disorders

    SBC: COG ANALYTICS, LLC            Topic: NIMHD

    DESCRIPTION provided by applicant Substance use disorders SUDs continue to be one of the most serious public health problems in the US Studies have consistently documented a substantially higher prevalence of SUDs among individuals under criminal justice supervision At year end approximately million adults were on probation or parole in adults African American probationer ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. A Tool for Research on Emotion in Naturally Occurring Speech

    SBC: Converspeech LLC            Topic: NLM

    DESCRIPTION provided by applicant A Tool for Research on Emotion in Naturally Occurring Speech It is now widely accepted that defects or limitations in emotion processing underlie many disorders such as anxiety depression bipolar and eating disorders If bio behavioral markers of emotions could be found researchers would have the basis for investigating emotions in both normal mental functi ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
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