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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Heterologous Production of Eleutherobin Precursors

    SBC: AMYRIS BIOTECHNOLOGIES            Topic: N/A

    DESCRIPTION (provided by applicant): Terpenoids are a diverse class of natural compounds with equally diverse and potent bioactivities. Because the practical use of terpenoids hinges on the ability to extract or synthesize these compounds, only the most abundant or easily synthesized compounds have been commercially developed. The long-term goal of this Small Business Technology Transfer Phase I p ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  2. Development of a novel whole blood coagulation assay

    SBC: HEMODYNE            Topic: N/A

    The inability to adequately monitor the effects of newer, potent anticoagulants is increasingly apparent. These powerful drugs have a very narrow therapeutic window. This is especially true in high-risk populations such as those with hepatic and renal dysfunction. Conventional monitoring parameters (i.e., PT, aPTT, INR) do not adequately measure or predict efficacy or toxicity for many of these ne ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  3. Bounding generalization risk for Deep Neural Networks

    SBC: EULER SCIENTIFIC            Topic: NGA20A001

    Deep Neural Networks have become ubiquitous in the modern analysis of voluminous datasets with geometric symmetries. In the field of Particle Physics, experiments such as DUNE require the detection of particle signatures interacting within the detector, with analyses of over a billion 3D event images per channel each year; with typical setups containing over 150,000 different channels.  In an ...

    STTR Phase I 2020 Department of DefenseNational Geospatial-Intelligence Agency
  4. Immune Attack: Simulation Game for Adolescent Education

    SBC: SIMQUEST INTERNATIONAL, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): This research project will develop an engaging game for high school students using simulation of immune cells in the human body fighting infection. The approach combines visually stunning 3D graphics and advanced training technologies including automated case scenario generation, intelligent tutoring, automated debriefing, live conferencing, and performance ass ...

    STTR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  5. Aerosolized hyaluronic acid as a treatment for emphysema

    SBC: EXHALE THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Chronic obstructive pulmonary disease afflicts 12-14 million people in the US and in an advanced form, emphysema, disables 2 million and ultimately leads to death. No approved, existing treatment can arrest emphysema's progressive destruction of the lung. Exhale Therapeutics, Inc intends to develop and commercialize aeros ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  6. A novel platelet inhibitor from bloodfeeding hookworms

    SBC: L2 DIAGNOSTICS LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Thromboembolic disease is a major cause of morbidity and mortality in the developed world. Because platelets play a critical role in the activation and propagation of thrombosis, they represent important targets for new anti-thrombotic drugs. A potent inhibitor of human platelet function has been isolated from the bloodfeeding hookworm, Ancylostoma caninum. ...

    STTR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  7. CELLULAR PSYCHOPHARMACOLOGICAL MONITORING SYSTEM

    SBC: Plastics One, Inc.            Topic: N/A

    N/A

    STTR Phase I 1998 Department of Health and Human Services
  8. Creating Research Files from CMS Data for Integration with Survey Data

    SBC: ACUMEN LLC            Topic: N/A

    DESCRIPTION (provided by applicant): This STTR proposal to the National Institute on Aging (NIA) requests funding to expand the capabilities of the Medicare Research Information Center (MedRIC) recently established by Acumen LLC with earlier support from NIA. The purpose of MedRIC is to facilitate the acquisition and linking of administrative data from the Centers for Medicare and Medicaid Service ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  9. TARGETED CPG OF CCR5 GENE--NOVEL HIV THERAPY

    SBC: SANGAMO BIOSCIENCES, INC.            Topic: N/A

    N/A

    STTR Phase I 1999 Department of Health and Human Services
  10. Image-Guided Minimally Invasive Robotic Surgery

    SBC: INTUITIVE SURGICAL            Topic: N/A

    DESCRIPTION (provided by applicant): Image-guided surgery allows surgeons to specifically target diseased tissue while sparing healthy tissue, reducing morbidity and improving patient outcomes. Minimally invasive surgical techniques deliver specific intervention without the morbidity associated with large open incisions. Image-guidance technology has the potential to provide significant benefit ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
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