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Award Data
The Award database is continually updated throughout the year. As a result, data for FY22 is not expected to be complete until September, 2023.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
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A Bioactive Prosthetic Vascular Graft
SBC: BIOSURFACES INC Topic: N/ADESCRIPTION (provided by applicant): Over 60,000 prosthetic grafts, which are comprised of either polyethylene terephthalate (polyester) or expanded polytetrafluoroethylene (ePTFE), are implanted in the United States each year. Medium (6-8mm) and small (l t5mm) internal diameter (I.D.) prosthetic arterial grafts continue to have unacceptably high failure rates when used in the clinical setting. T ...
STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health -
A Nanofibrous Bioactive Prosthetic Sewing Cuff
SBC: BIOSURFACES INC Topic: N/ADESCRIPTION (provided by applicant): Cardiac valve replacement using prosthetic valves is indicated when progression of degenerative disease or bacterial infection of the native valve results in valvular dysfunction, thereby impacting on cardiac output. An estimated 50,000 prosthetic valves are implanted annually in the United States, with this number increasing due to an aging population and, to ...
STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health -
A Bioactive Prosthetic Vascular Graft
SBC: BIOSURFACES INC Topic: NHLBIDESCRIPTION (provided by applicant): Over 60,000 prosthetic grafts, which are primarily comprised of polyethylene terephthalate (polyester) or expanded polytetrafluoroethylene (ePTFE), are implanted in the United States each year. Unfortunately, these grafts continue to have high failure rates due to secondary complications associated with acute thromboses and incomplete, unregulated cellular prol ...
STTR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health -
Selective activation of the vagus nerve as an improved therapy for heart failure
SBC: BLACKROCK MICROSYSTEMS, INC Topic: NHLBIDESCRIPTION (provided by applicant): The goal of the proposed project is to alleviate the enormous public health burden of heart failure. Heart failure leads to significant morbidity and mortality, affects almost five million Americans, and results in morethan 35 billion dollars in annual healthcare costs. Current pharmacological and surgical treatments are only moderately effective and can have s ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Development of Improved Spin Probes for Aging Research
SBC: TDA RESEARCH, INC. Topic: N/ADESCRIPTION (provided by applicant): There is currently a need for improved spin probes to help with the diagnosis of and fundamental research into diseases mediated by reactive oxygen species (ROS). This is especially true for the study of age related diseases, since oxidative damage accumulates during the aging process, and many age related disorders such as Parkinson's and Alzheimer's disease a ...
STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health -
Lanthanide Radionuclide Production
SBC: TDA RESEARCH, INC. Topic: N/ADESCRIPTION (provided by applicant): Major advances have recently been made in the development of monoclonal antibody-based radioimmunotherapy cancer treatments, and several of these next generation antibody treatments have demonstrated good efficacy in hu man trials and are currently awaiting FDA approval. With this new generation of highly engineered monoclonal antibodies comes the need for a wi ...
STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
