Award Data

Project Summary Abstract Development of Optimized Endectocide treated Bird Feed Formulations for West Nile Virus Control STTR Phase I Application PIs Brady Clapsaddle TDA Research Inc Dr Brian Foy Colorado State University West Nile Virus WNV is the leading cause of domestically acquired arboviral disease in the United States resulting in significant disease and death every year in both ...

Project Summary AbstractDevelopment of a Nerve Cuff Electrode from Soft and Elastomeric Conducting Wires STTR Phase I ApplicationPIBrady ClapsaddleTDA ResearchIncBio electronic interfaces are used in a wide array of applications for recording and providing electrical impulses to treat diseaseOne common interface device for the PNS is the cuff electrodeCurrent cuff electrodes have many failure mode ...

DESCRIPTION provided by applicant Like all neurons of the central nervous system CNS retinal ganglion cells fail to regenerate and often die after damage to the optic nerve such as occurs in optic nerve stroke or other optic neuropathies Loss of axonal connectivity and neuronal death that occurs after damage to the optic nerve results in vision loss While therapeutics targeting secondary ...

DESCRIPTION provided by applicant RAP as a therapeutic compound for neuronal regeneration after spinal cord injury Novoron Bioscience Inc RESEARCH andamp RELATED Other Project Information Project Summary There are an estimated to new cases of spinal cord injury SCI each year and million people in the United States are paralyzed in some form due to SCI Currently ther ...

7. Project Summary Multiple sclerosis (MS) is a neurodegenerative disease in which myelin of the central nervous system (CNS) is destroyed by a self-reactive immune response. This demyelination is accompanied by the death of the myelinating cells themselves, the oligodendrocytes. Repeated bouts of demyelination leave the denuded CNS neurons vulnerable to degradation and is the major cause of neuro ...

7. Project Summary Alzheimer’s disease (AD) is the most common cause of dementia and is a growing problem as populations age. More than 25 million people are affected by dementia worldwide with most suffering from AD. AD is characterized by the presence of plaques of insoluble amyloid-beta (Aβ) and tangles of hyperphosphorylated aggregates of the cytoskeletal protein, tau. Thus far, most AD tre ...