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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Validation and Quantification of FFPE Antigen Retrieval by Proteome Analysis

    SBC: CALIBRANT BIOSYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Because of the long history of the use of formalin as the standard fixative for tissue processing in histopathology, there are a large number of archival formalin-fixed and paraffin-embedded (FFPE) tissue banks worldwide. These FFPE tissue collections, with the attached clinical and outcome information, present invaluable resources for conducting retrospective ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  2. VALIDATION AND QUANTIFICATION OF FFPE ANTIGEN RETRIEVAL BY PROTEOME ANALYSIS

    SBC: CALIBRANT BIOSYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Because of the long history of the use of formalin as the standard fixative for tissue processing in histopathology, there are a large number of archival formalin-fixed and paraffin-embedded (FFPE) tissue banks worldwid e. These FFPE tissue collections, with attached clinical and outcome information, present invaluable resources for conducting retrospective pro ...

    STTR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  3. Validation of a Diagnostic Test for Borrelia miyamotoi

    SBC: L2 DIAGNOSTICS LLC            Topic: NIAID

    ABSTRACT Borrelia miyamotoi is a tick transmitted spirochete recently shown to cause infection and disease in the United StatesEurope and AsiaA member of the relapsing fever group of Borreliathis pathogen has been proven to cause most commonly a nonspecificflu like illness with feverfatiguemyalgiaand headacheDisease can be particularly severe and involve the central nervous system in immunocomprom ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Validation of a Novel Treatment for Glioblastoma

    SBC: CURTANA PHARMACEUTICALS INC            Topic: NCI

    ? DESCRIPTION (provided by applicant): The goal of this application is to study in vivo efficacy of CT102, a newly discovered inhibitor of the OLIG2 transcription factor in animal models of glioblastoma (GBM), a highly underserved area of pharmacotherapy. In this proposal, the experienced drug discovery group at Curtana Pharmaceuticals Inc. will conduct a pre-clinical evaluation of selectivity ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. VARIATION SCANNING WITH MISMATCH REPAIR DETECTION MRD)

    SBC: PARALLELE BIOSCIENCE, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): One widely considered approach to identify susceptibility alleles is through linkage disequilibrium (LD) between these alleles and a universal set of relatively frequent SNPs distributed in all or most ethnic populations. This approach, however, may be unrealistic when variant alleles responsible for disease susceptibility are infrequent or are specific to a pa ...

    STTR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  6. Variation Scanning with Mismatch Repair Detection (MRD)

    SBC: PARALLELE BIOSCIENCE, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): One widely considered approach to identify susceptibility alleles is through linkage disequilibrium (LD) between these alleles and a universal set of relatively frequent SNPs distributed in all or most ethnic populations. This approach, however, may be unrealistic when variant alleles responsible for disease susceptibility are infrequent or are specific to a pa ...

    STTR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  7. Ventilation Stethoscope using Hyperpolarized Xenon

    SBC: MIRTECH INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Ventilator Induced Lung Injury (VILI) is a common cause of morbidity and sometimes mortality in critically ill patients with respiratory failure. The types of VILI include barotraumas, volutrauma, atelectrauma, and biotrauma. Thus ventilator setting is a delicate balance between achieving sufficient ventilation but avoiding excessive pressure and overdistensio ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  8. Veristride STEP-R: an interactive verbal/auditory gait trainer

    SBC: Veristride, Inc.            Topic: 600

    Veristride IncProject Summary When surveyedof stroke survivors said the ability toget out and aboutis considered between important and essential for a better lifeHoweverthat desire falls short of reality for most stroke survivorsOftenwalking across a neighborhood street or from a car to a home is an insurmountable task with little opportunity for working on improvement in gaitOnce insurance covera ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Very Low-Cost C-Scan Ultrasonic Imaging

    SBC: POCKETSONICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This Phase I STTR proposal seeks funding to support development and evaluation of a prototype low-cost, easy to use and portable ultrasound imaging system. There are many applications in clinical medicine where such a transcutaneous imaging system would be of great value. For this proposal, our main focus is to provide guidance for intravenous catheter insertio ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  10. Very Low-Cost C-Scan Ultrasonic Imaging

    SBC: POCKETSONICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this program is to save lives and improve the quality of care of people requiring vascular access by enabling quicker access and minimizing failed attempts. Direct visualization of target vessels with ultrasound imaging will minimize number of attempts and failed attempts, thus allowing more rapid vascular access for administration of IV fluids or m ...

    STTR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
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