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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Targeting MtrAB of M. tuberculosis

    SBC: Sequella, Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): Tuberculosis (TB) has a massive impact on global health. The World Health Organization estimates that one- third of all people worldwide harbor latent TB infections, with sixteen million cases of active disease and nearly two million deaths caused by Mycobacterium tuberculosis (MTB) each year. TB infections are heterogeneous, and current medicines do not work e ...

    STTR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  2. A non-invasive, automated platform for hemodynamic assessment of patients at risk of heart failure or pulmonary hypertension

    SBC: SENSYDIA CORPORATION            Topic: NHLBI

    PROJECT SUMMARY Heart failure (HF) and abnormal heart function directly affects 6 million people in the U.S. and is a leading cause of death. Early intervention is key to reducing mortality and morbidity, yet early diagnosis, particularly for those with asymptomatic disease, is challenging. Effective diagnosis and management of HF and accompanying pulmonary hypertension (PH) requires accurate meas ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  3. Using Interactive Digital Media to Teach Cardiopulmonary Resuscitation to High School Students

    SBC: CORAM TECHNOLOGIES, INC.            Topic: 400

    Summary Abstract Out of hospital cardiac arrest affects overpeople in the U Sannuallybut onlysurviveBystander cardiopulmonary resuscitationCPRimproves survivalbut rates of training in the U Sare lowIt is recently required by law inU Sstates that high school students learn CPRHoweverthere is great variability nationwide in howby whomand when students are taughtAdditionallycurrent methods of teachin ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Using Interactive Digital Media to Teach Cardiopulmonary Resuscitation to High School Students

    SBC: CORAM TECHNOLOGIES, INC.            Topic: 500

    Abstract Out-of-hospital cardiac arrest affects over 350,000 people in the U.S. annually, but only 10.8% survive. Bystander cardiopulmonary resuscitation (CPR) improves survival, but rates of training in the U.S. are low. It is recently required by law in 39 U.S. states that high school students learn CPR. However, current methods of teaching CPR use outdated pedagogical strategies and expensive d ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  5. Smartphone-based rewards as a bridge to treatment for naloxone reversal patients

    SBC: DYNAMICARE HEALTH INC            Topic: NIDA

    ABSTRACT Opioid overdose is a major public health crisisand a clear sign of problem drug useMany people who experience an overdose receive a naloxone reversal and are treated in a hospital emergency departmentHoweverfew overdose survivors enroll in treatmenteven if they receive care and referral to treatment while in an emergency departmentMedication assisted treatmentsMATsuch as methadone or bupr ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Catheter Development for Epicardial Atrial Gene Painting

    SBC: RITHIM BIOLOGICS INC.            Topic: NCATS

    ABSTRACT Atrial fibrillationAFis the most common rhythm disturbance in the US and other developed countriesAF significantly affects the lives of the afflictedcausing symptoms that range from palpitations to fatigueweakness and activity intoleranceand substantially increasing the risks of strokecongestive heart failure and deathThe impact on public health is substantialwith more thanhospital admiss ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Software to compute sample size for high-volume genetic studies

    SBC: CHERYL FAUCETT            Topic: N/A

    DESCRIPTION (provided by applicant): In the study of complex traits such as cancer, heart disease, and asthma, it is essential for investigators to have an honest estimate of required sample size when they design their studies. This is particularly true in the modern era of high-volume genetic studies, including pathway-based candidate-gene and genome-wide association studies, as they typically re ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  8. Aminonaphthyridine compounds as potential therapeutics for lung and thyroid cancers

    SBC: KINARX, INC            Topic: 102

    Over the past three decades a growing number of cancer-driving protein kinases have been successfully targeted as reflected in the approval of 49 kinase inhibitors by the Food and Drug Administration (FDA). Recent approval of the first tyrosine kinase inhibitor (Larotrectinib) for treatment of any cancer bearing mutation in neurotrophic receptor kinase validated a novel paradigm of precision targe ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  9. Leveraging platelet signal transduction for personalized antiplatelet therapy

    SBC: PLATELETDIAGNOSTICS, LLC            Topic: NHLBI

    Project Summary/Abstract Platelet-mediated thrombosis causes both coronary arterial disease (CAD) and stroke, the first and fifth most common causes of mortality in the US. Antiplatelet agents, typically aspirin and/or clopidogrel, significantly improve survival in patients with CAD or stroke and have remained a mainstay of treatment for more than two decades. Yet despite the consensus that platel ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  10. Wearable Sternal Skin Conductance Device for Hot Flashes

    SBC: METIS DESIGN CORPORATION            Topic: N/A

    Abstract: The majority of American women transitioning through the menopause will experience hot flashes. However, safe and effective treatments for hot flashes are currently lacking. Investigation of new treatments for hot flashes has been limited by the measurement of hot flashes. Current gold standard physiologic measures of hot flashes have key limitations, including electrode design, monitor ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
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