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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. PD Wii: Computer-Based Training Phase II

    SBC: RED HILL STUDIOS            Topic: N/A

    DESCRIPTION (provided by applicant): Red Hill Studios and the University of California, San Francisco (UCSF) School of Nursing proposes to develop a computer-based videogame training program for patients with Parkinson's disease (PD). The program will feature a customizable Physical Gaming Regimen that will be based on an existing training program that has proven to be effective in improving gait ...

    STTR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  2. DNA HELICASE AND PRIMASE INHIBITORS FOR BIODEFENSE

    SBC: MICROBIOTIX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The increasing prevalence of antibiotic-resistant strains of bacterial pathogens represents a major unmet medical need. Naturally occuring or intentionally engineered drug-resistance in biothreat agents is also a serious risk for biodefense. The development of new antibiotics against unexploited targets with novel mechanisms of action is a vital part of the sol ...

    STTR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  3. New Rapid Diagnostic Tests for Amebiasis

    SBC: TECHLAB, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Our goal is to produce point-of-care diagnostic tests for amebiasis. Entamoeba histolytica is a protozoan parasite and the causative agent of amebiasis in humans. Intestinal amebiasis causes debilitating diarrhea and dysentery, while extraintestinal amebiasis occurs when the parasite migrates from the intestinal tract to organs throughout the body, most commonl ...

    STTR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  4. Scanning Chlamydia proteome for vaccine antigens

    SBC: ImmPORT Therapeutics Inc dba Antigen Discovery Inc            Topic: N/A

    DESCRIPTION (provided by applicant): Throughout the World Chlamydia trachomatis is the most common sexually transmitted bacterial pathogen. In areas with poor sanitary conditions C. trachomatis causes trachoma the most common cause of preventable blindness in the World. In symptomatic cases, unless therapy is implemented in a timely manner, long-term sequelae including, pelvic inflammatory disease ...

    STTR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  5. Novel Bone Graft Material With Osteoinductive and Hemostatic Function

    SBC: CEREMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Bone is one of the most implanted materials in the body, second only to blood. The market for bone grafting and dental implants is currently over 4.8 billion and is expected to grow rapidly in the future. Autograft has traditionally been used, but limited supply, donor-site risks, and cost created a demand for bone graft substitutes. As an osteoinductive bone ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  6. Flexible Ion-Mediated Artificial Retina

    SBC: LAMBDAVISION INCORPORATED            Topic: NEI

    DESCRIPTION (provided by applicant): A flexible, protein-based, ion-mediated retinal implant is proposed for the restoration of vision for patients with retinal degenerative diseases, such as age-related macular degeneration (AMD) and retinitis pigmentosa(RP). The implant under development uses the retinal- containing protein, bacteriorhodopsin (BR), to convert light into a pH gradient. This gradi ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Targeting MtrAB of M. tuberculosis

    SBC: Sequella, Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): Tuberculosis (TB) has a massive impact on global health. The World Health Organization estimates that one- third of all people worldwide harbor latent TB infections, with sixteen million cases of active disease and nearly two million deaths caused by Mycobacterium tuberculosis (MTB) each year. TB infections are heterogeneous, and current medicines do not work e ...

    STTR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  8. Software to compute sample size for high-volume genetic studies

    SBC: CHERYL FAUCETT            Topic: N/A

    DESCRIPTION (provided by applicant): In the study of complex traits such as cancer, heart disease, and asthma, it is essential for investigators to have an honest estimate of required sample size when they design their studies. This is particularly true in the modern era of high-volume genetic studies, including pathway-based candidate-gene and genome-wide association studies, as they typically re ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  9. Wearable Sternal Skin Conductance Device for Hot Flashes

    SBC: METIS DESIGN CORPORATION            Topic: N/A

    Abstract: The majority of American women transitioning through the menopause will experience hot flashes. However, safe and effective treatments for hot flashes are currently lacking. Investigation of new treatments for hot flashes has been limited by the measurement of hot flashes. Current gold standard physiologic measures of hot flashes have key limitations, including electrode design, monitor ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  10. C/EBP-beta PEPTIDES FOR THE TREATMENT OF LIVER INJURY AND FIBROSIS

    SBC: XFIBRA, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Activation of hepatic stellate cells (HSC) is responsible for the development of liver fibrosis in chronic liver diseases of all causes and remarkably, HSC clearance by apoptosis may allow recovery from liver injury andreversal of liver fibrosis. There is full agreement among liver fibrosis experts that inhibiting o reversing HS activation (the therapeutic targ ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
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