You are here

Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Antibacterial nanoparticles as insecticide synergists and insect growth regulators for improved control of cockroach infestations

    SBC: Apex Bait Technologies, Inc.            Topic: NIAID

    PROJECT SUMMARY The prevalence of asthma in the United States is approximately 8% (andgt;25 million people). In African Americans, the prevalence is andgt;11%. A majority of asthma sufferers are sensitized to allergens, including those shed in the feces, saliva, and exuviae of cockroaches. Thus, exposure to cockroach infestation is recognized as both a significant risk factor for the development o ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  2. Translation of Interferometric-based Free-solution Assay Methodology

    SBC: MERU BIOTECHNOLOGIES            Topic: 300

    Project Summary: Lung cancer is the leading cause of cancer-related deaths in the United States. Low dose chest computed tomography (CT) screening programs that target high-risk individuals can reduce lung cancer-specific mortality by 20% and overall mortality by 6.9%. There is a growing movement to implement this life saving screening into routine practice, with endorsements from the U.S. Prevent ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  3. Brillouin optical eye scanner prototypes for commercialization

    SBC: INTELON OPTICS, INC.            Topic: 100

    ABSTRACT The overall goal of this STTR project is to commercialize a novel optical eye scanner device capable of measuring the biomechanical properties of tissues via Brillouin light scattering. The Brillouin technology invented in the co-PI’s lab has shown broad potential for improving the diagnosis and treatment of vision disorders. Clinical data obtained with current laboratory systems reveal ...

    STTR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
  4. Multistage LC-MSn for automated glycan isomer assignment of glycopeptides

    SBC: PROTEIN METRICS INC            Topic: 400

    N- and O-linked glycosylation are some of the most common, abundant, and biologically important posttranslational modifications of proteins, yet they are also some of the most difficult to study. The dominant analytical platform for the study of glycosylation is mass spectrometry, yet this platform on its own is incomplete, because it cannot elucidate glycan topology and linkage stereochemistry. T ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  5. A multitargeted nanocarrier inhibitor of undruggable transcription factors for treating castration resistant prostate cancer

    SBC: PARABON NANOLABS, INC.            Topic: 102

    Project Summary This project addresses the critical need for treatments of castration resistant prostate cancer (CRPC) by proposing to engineer and develop a novel, nanostructured pharmaceutical (P-TRIS5) which will target tumor cells and deliver two potent, synergistic therapeutics (an siRNA and a small molecule) to inhibit the androgen receptor and RUNX, two commonly implicated transcription fac ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  6. Leveraging an academic-industry partnership to develop a cancer-specific mobile meditation app

    SBC: Calm.com, Inc.            Topic: 102

    1 Project Summary/Abstract2 Approximately 15.5 million US cancer patients/survivors experience a host of residual symptoms (e.g.,3 fatigue, anxiety, depression, pain, sleep disturbance) and reduced quality of life that are often not resolved with4 even the best-available current standard of care therapies. Residual symptom burden impairs cancer survivor5 functioning and leads to increased rates of ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  7. HBI-002 to Treat Parkinson’s Disease

    SBC: Hillhurst Biopharmaceuticals, Inc.            Topic: 107

    PROJECT SUMMARY The goal of the proposed project is to evaluate the potential of HBI-002, a novel oral formulation of carbon monoxide (CO), as a neuroprotective agent in Parkinson’s disease (PD). A growing body of research suggests that low doses of CO - and the heme oxygenase (HO) enzymes that generate endogenous CO - protect against neuronal cell loss in PD, and epidemiologic studies have asso ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  8. Development of perivascular space mapping toolset as a diagnostic aid for Alzheimer's disease

    SBC: NEUROSCOPE INC.            Topic: NIA

    Project Summary Alzheimer’s disease (AD) is a devastating disease that affects millions of Americans and imposes a huge socio- economic burden. AD-related cognitive decline is associated with the accumulation of Aβ (Amyloid beta) plaques and neurofibrillary tangles of hyperphosphorylated tau protein, which are insufficiently cleared and degraded by mechanisms such as the glia-lymphatic system o ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  9. Computational prediction of gut microbiome-mediated drug metabolism

    SBC: NEXILICO, INC.            Topic: 100

    Project Summary / Abstract Notwithstanding pre-clinical experiments and clinical trials performed to identify efficacy, side effects, and adverse drug reactions (ADRs), only 25-60% of patients respond favorably to prescribed drugs, leading to a cost of $30-$130 billion in the US annually. ADRs are partially attributed to the gut microbiome, i.e. the complex and dynamic community of microorganisms ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  10. Development of a Bio-tissue Oxygenation Nanophosphor Enabled Sensing (BONES) system for Quantifying Hypoxia in Bone Marrow

    SBC: SIGRAY, INC.            Topic: 400

    Project Summary/Abstract Low oxygen (hypoxic) environments are known to be important for maintaining the small number of adult stem cells in the human body, such as in bone marrow. These conditions are also believed to enable dormant cancer cells to survive and metastasize years or decades after the original tumor has been destroyed and the reason why bone marrow is one of the most common sites of ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
US Flag An Official Website of the United States Government