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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 171 - 180 of 207712 results
  1. CN-105 Improves Functional Outcome After Intracranial Hemorrhage

    SBC: AegisCN LLC            Topic: 106

    Annually, approximately 100,000 patients in the USA suffer from intracerebral hemorrhage (ICH), which is associated with high mortality rates and poor long-term cognitive and physical recovery. At present, no pharmacological therapies have been demonstrated to improve functional outcomes after ICH. However, we have successfully demonstrated that CN-105, a pentapeptide derived from the receptor bin ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  2. Novel therapy for arthrofibrosis

    SBC: Panorama Research Incorporated            Topic: NIAMS

    Novel therapy for arthrofibrosis AbstractArthrofibrosis (AF) is a common result of joint surgeries. The formation of collagen-rich fibrotic scars is unconditionally necessary for AF and suggests an effective therapeutic approach. Collagen fibrils are formed in the extracellular space by aggregation of individual collagen I molecules (monomers) produced by cells in response to injury. The assembly ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  3. Boron-containing antimalarial drug discovery

    SBC: REACTIVE BIOSCIENCES INC            Topic: NIAID

    PROJECT SUMMARY New drugs to treat malaria, ideally with unique chemical structures and mechanisms of action, are urgently needed. Optimal drug candidates for the treatment and prevention of malaria will have potent activity against cultured parasites and in animal models of malaria, be rapidly active against erythrocytic malaria parasites, be orally bioavailable, have extended pharmacological exp ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  4. Low-Cost, Single-Use Trans-Nasal Cryotherapy Device for Low-Resource Settings

    SBC: RAHIMZADEH JASON            Topic: 102

    PROJECT SUMMARY/ABSTRACT Esophageal cancer is an aggressive disease with a five-year survival rate below 20 percent. The incidence of this cancer has increased dramatically over the last 50 years and is projected to continue increasing at least until 2030. Chronic acid reflux leads to changes in the lining of the esophagus and the development of Barrett’s Esophagus in some patients. Patients wit ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  5. Implementing and Scaling the STEADI Fall Prevention Algorithm Using a Conversational Relational Agent for Community-Dwelling Older Adults with and without Mild Cognitive Impairment (MCI).

    SBC: CARE.COACH CORPORATION            Topic: NIA

    ABSTRACT Falls are a serious threat to the health and well-being of older Americans, especially those with mild cognitive impairment (MCI) and dementia due to the role cognition plays in gait. Falls are the leading cause of injury- related deaths among Americans ≥ 65 years of age (older adults), and the age-adjusted rate of deaths from falls is increasing. One in three older adults falls each ye ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Sub-One PUE through Silicon Cooling Efficiency

    SBC: JETCOOL TECHNOLOGIES INC            Topic: 1

    To achieve a quantum step in data center efficiency, new thermal management technologies must be coupled to the devices they cool. This proposal seeks to build on recent observations that microconvective cooling not only functions as a high-performance chip cooling technique with the potential for a low PUE, but is also capable of increasing the intrinsic efficiency of the silicon processors them ...

    SBIR Phase II 2023 Department of EnergyARPA-E
  7. Sub-One PUE through Silicon Cooling Efficiency

    SBC: JETCOOL TECHNOLOGIES INC            Topic: 1

    To achieve a quantum step in data center efficiency, new thermal management technologies must be coupled to the devices they cool. This proposal seeks to build on recent observations that microconvective cooling not only functions as a high-performance chip cooling technique with the potential for a low PUE, but is also capable of increasing the intrinsic efficiency of the silicon processors them ...

    SBIR Phase I 2023 Department of EnergyARPA-E
  8. High performance polymer for dust tolerant extreme environment bearings

    SBC: ATSP Innovations, Inc.            Topic: S4

    In Phase I, we demonstrated ATSP-based coatings vs. ATSP-based coatings have excellent tribological performance: low coefficient of friction (COF) and ldquo;zero wearrdquo; in a widet emperature application range (from -196deg;C to 300deg;C). Additionally, for ATSP-based coatings, the 50-year equivalent low-earth-orbit proton exposure had no effect on its tribological performance. This excellent t ...

    SBIR Phase II 2023 National Aeronautics and Space Administration
  9. Tether blue sUAS with modular payload capability for emergency response mission set

    SBC: EASY AERIAL INC            Topic: AFX236DPCSO1

    Air Force bases face numerous physical security and other challenges that require immediate response and constant vigilance.  Situational awareness and the ability to respond are critical to Airmen and others’ safety and security.  In the United States, m

    SBIR Phase II 2023 Department of DefenseAir Force
  10. C17 Globemaster III Nucleated Foam On-wing engine performance restoration

    SBC: AEROCORE TECHNOLOGIES LLC            Topic: AFX236DPCSO1

    The United States Air Force (USAF) aims to enhance the energy efficiency and readiness of the C-17 Globemaster III through the application of AeroCore's advanced technologies. These technologies, including Nucleated Foam Technology and On-Wing Restoration

    SBIR Phase II 2023 Department of DefenseAir Force
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