Award Data

Multidimensional flow cytometry allows the discrimination of neoplastic cells from their normal counterparts. Using technology for the simultaneous measurement of 5 parameters, the abnormal expression of normal antigens can be used to identify leukemic populations. Distinction between normal and abnormal cells can be made by a highly trained scientist using a computer program which permits visuali ...

In this study, we will explore the development of an automated cervical analysis system for useafter manual screening of thinlayer cervical specimens as a quality control (QC) instrument. We shall testthe hypothesis that nuclear features termed "Malignancy Associated Changes" (MACs) measured by theinstrument can be employed to identify disease in samples found to be false negative by manualmethods ...

AS PROSTATE CANCER HAS RECENTLY BECOME THE MOST WIDELY DIAGNOSED FORM OF CANCER IN UNITED STATES' MALES, CLINICIANS ARE EXPECTED TO SEEK MORE EFFECTIVE TREATMENT MODALITIES. ONE OF THESE MAY BE HYPERTHERMIA AS AN ADJUNCT TO RADIATION AND CHEMOTHERAPY. THE MAIN LIMITATION TO THIS MODE OF THERAPY HAS BEEN THE LACK OF EFFECTIVE HEATING EQUIPMENT FOR THE PROSTATIC REGION. A NOVEL TWO-APPLICATOR MICROW ...

We will develop a computer program which will be used as an integral part of intravascular ultrasonic units for assessing the severity of arterial lesions. The software will use the digitized vessel geometry data directly from the units to produce a quantitative assessment of stenosis severity using fluid dynamics, stress analysis methods, and catheter derived flow and pressure data. The assessmen ...

This proposal focuses on the development of an in-situ atmospheric sensor capable of identifying and evaluating regions of corrosion occurring specifically on aircraft. The sensor is antiucipated to have an electrode applied on the coating of the test coupon. When this electrode and coupon are exposed to moisture, either by immersion or high humidity, the near de impedance of the coating-metal sys ...

The proposed research will determine the feasibility of developing a Hyperspectral InfraRed Imager (HIRI). This imager will be used to collect spatial and spectral data from ground based and airborne perspectives, which will then be used in conjunction with a computer based target identification process. The long term goal is to identify the targets of interest in real time using an automated re ...

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Businesses seeking to participate in NIST programs or to acquire technology from a federal laboratory are faced with a confusing myriad of starting points. Typically, time and money is expended to qualify the benefit of any program or technology. Even when the search is successfully concluded, it is common for the business or the federal contract to lack resources necessary to yield a commercial ...

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