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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Assessment of mobile application-delivered lighting interventions for reducing circadian disruption in shift workers

    SBC: ARCASCOPE INC.            Topic: NHLBI

    PROJECT SUMMARY Shift workers experience profound circadian disruption, which can have deleterious long term effects on their health and quality of life. Mood, fatigue, and performance can be improved in shift workers by moving the timing of their peak circadian drive to sleep outside the hours they are expected to work. This can be achieved with a targeted lighting intervention, as light is the p ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  2. Solving Sepsis: Early Identification and Prompt Management Using Machine Learning

    SBC: Cohere-Med, Inc.            Topic: 300

    Abstract This fast-track STTR application proposes to enhance, validate, and scale Sepsis Watch, a deep learning sepsis detection and management system built using data from the Emergency Department (ED) Duke University Hospital (DUH). The proposal will extend and enhance Sepsis Watch to EDs, general inpatient wards, and intensive care unit (ICU) settings across multiple health systems in the Unit ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  3. Diagnosis of Esophageal Squamous Cell Carcinoma in Low-Income Countries

    SBC: CAPSULOMICS INC            Topic: 102

    Esophageal squamous cell carcinoma (ESCC) causes more than 509,000 deaths per year worldwide, and over 80% of these cases occur in low- and middle-income countries (LMICs). In the settings where it is available and affordable, ESCC diagnosis is made using the highly invasive and expensive procedure known as esophagogastroduodenoscopy (EGD, also referred to as upper endoscopy). However, citizens of ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  4. Triagonist Peptide Therapeutics for Neuroprotection

    SBC: VELUM INC            Topic: 300

    Project Summary Morbidity associated with neuronal degeneration and dysfunction poses an increasing public health burden. Among the wide range of etiologies that result in neuronal dysfunction, including chronic conditions such as Alzheimer’s and Parkinson’s disease and vascular dementias, one major cause that has been largely unnoticed but is increasingly recognized as a major concern is trau ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  5. Heteroduplex thermostable ligation assembly: a new platform to rapidly generate large DNA molecules

    SBC: CHESAPEAKE GENOMIC SYSTEMS, LLC            Topic: 400

    In vitro assembly of DNA fragments andgt;20 kb has recently identified as a critical technical challenge for writing synthetic genomes. Meeting this challenge will increase the efficiency of genome writing projects that depend on large synthetic DNAs, which are iteratively recombined to replace chromosome regions in a step-wise manner to partially or completely re-write bacterial or yeast chromoso ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  6. A two-dimensional antiscatter grid for dental cone beam computed tomography

    SBC: M2 Technologies LLC            Topic: NIDCR

    Project summary Cone beam computed tomography (CBCT) is a commonly used 3D x-ray imaging modality in dental and craniofacial imaging. While CBCT is primarily employed in evaluating bony anatomy in 3D, soft tissues are often poorly visualized in dental CBCT images. Moreover, tissue densities cannot be extracted accurately from CBCT images. The main culprit behind this problem is scattered radiation ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  7. The Nanopore-based Ion Selective Electrode Vial

    SBC: ELECTRONIC BIOSCIENCES, INC.            Topic: 400

    Project Summary An electrolyte panel is a blood test that measures the levels of electrolytes and carbon dioxide in your blood. Electrolytes are chemicals found naturally in the body, such as potassium, calcium, sodium, and are needed to keep the bodyandapos;s balance of fluids at the proper level and to maintain normal functions, such as heart rhythm, muscle contraction, and brain function. CO2 i ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  8. Development of low-cost, field-ready nanobodies against snake venom

    SBC: Venomyx, Inc.            Topic: 400

    PROJECT SUMMARY Snakebite constitutes one of the largest and most tenacious public health issues on a global scale. Every year, up to 5 million people will suffer snakebite envenomation, causing approximately 125,000 deaths and 400,000 left with permanent physical disability. Nearly 8,000 snakebites occur in the United States each year. The regions most affected are in Asia, Africa, Latin America, ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  9. Polymer use in Preservation of Tissue Perfusion to Address Sepsis

    SBC: PERFUSION MEDICAL LLC            Topic: 300

    Perfusion Medical is commercializing a novel pipeline product called PEG-20k IV Solution. The company believes this may be the first therapeutic to directly treat lethal complications of sepsis, and as such, support new thinking on the basic mechanisms of the disease. Sepsis or septic syndrome leads to a spectrum of illnesses and occurs at a frequency of 1.7 million people in the US each year and ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  10. A Mobile Tai Chi Platform for Fall Prevention in Older Adults

    SBC: BIOSENSICS LLC            Topic: NIA

    Project Summary Exercise-based interventions have been recently shown to have great potential for preserving and restoring cognitive function in older adults. In this context, Tai Chi has gained the interest of researchers and clinicians because it incorporates physical, cognitive, social, and meditative components within the same activity. Such multimodal exercise modality is expected to have a p ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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