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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. CBRN Sensor and Sensor Netting Algorithms

    SBC: Torch Technologies, Inc.            Topic: CBD09110

    This Phase I SBIR proposal presents the Torch Technologies approach for the development of advanced, innovative, robust real-time algorithms for the integration of passive and active electro-optical sensor detections and identification information. In our proposal, we detail our ideas regarding the optimal fusion of Chemical Warfare (CW) agent sensor data within the innovative data fusion archite ...

    SBIR Phase I 2009 Department of DefenseOffice for Chemical and Biological Defense
  2. Geo And Ortho Rectified Video With Fused 3d Mapping, Light Detection And Ranging (LIDAR), And Live Video Overlays

    SBC: TOYON RESEARCH CORPORATION            Topic: SOCOM09003

    While full motion video (FMV) data contains a wealth of information, its potential for providing actionable intelligence cannot be realized unless the data is provided within its geographic context and is correlated with available intelligence from human assets. To provide the necessary contextual, registration to/fusion with GIS data is a natural choice. This requires both geo- and ortho-rectific ...

    SBIR Phase I 2009 Department of DefenseSpecial Operations Command
  3. Compact, Efficient Motor Controllers with Active Noise Cancellation

    SBC: Applied Physical Sciences Corp.            Topic: SOCOM09005

    Most commercial motor controllers (MC’s) operate at relatively low switching frequency that produces a detectable acoustic signature and therefore drives the Navy to procure MC’s operating at higher frequencies in order to reduce acoustic signature. These custom MC’s, however, still generate significant noise, are not sufficiently reliable, and have obsolete components. APS will develop an i ...

    SBIR Phase I 2009 Department of DefenseSpecial Operations Command
  4. Nanoparticle Adhesive Deposition Process for Metal Hydroxide Nanoplatelets

    SBC: Physical Optics Corporation            Topic: SOCOM10007

    To address the USSOCOM need to develop new materials or processes using nanotechnology for chemical and biological warfare (CBW) defense, Physical Optics Corporation (POC) proposes to develop a new Nanoparticle Adhesive Deposition (NANOPAD) process. This proposed process is based on established chemical finishing techniques using chemically synthesized metal hydroxide nanoplatelets (MHN) to impreg ...

    SBIR Phase I 2010 Department of DefenseSpecial Operations Command
  5. Microfluidic High-throughput Platform for Determining of Kinetic Constants of Enzyme Variants

    SBC: CFD RESEARCH CORPORATION            Topic: CBD10107

    Molecular biology techniques allow generating combinatorial libraries of large number of enzyme variants. However, there is currently no technology available for screening the enzyme libraries for identifying variants with improved activity for the substrate. We propose to develop a novel, microfluidic, high-throughput platform for determining kinetic constants of enzyme variants and identifying v ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  6. A Novel Microfludic Device for Drug Toxicity Studies

    SBC: CFD RESEARCH CORPORATION            Topic: CBD10103

    Current drug discovery and development programs are severely limited by the expensive animal trials and oversimplified in vitro models. Results obtained from the in vitro models are not predictive of in vivo toxicity owing to significant difference in testing from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device for quantitati ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  7. In vitro Models Suitable for High-throughput Screening of Drug Toxicities in Human Tissues

    SBC: Nico Technologies Corp.            Topic: CBD10103

    The drug R&D cycle is long and very expensive. In many ways, this status quo can no longer be sustained. One of the reasons for such great cost is that the vast majority of drug candidates are screened out at the stages of animal and human trials. More efficient methods of testing of drugs at the stage of ex-vivo studies, which are substantially less expensive than animal and human testing cyc ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  8. Multifunctional Antisense Therapeutics Nanocarrier and Inhalation Device

    SBC: Physical Optics Corporation            Topic: CBD10102

    To address the CBD need for improved formulations to enhance the ease of use and bioavailability of antisense therapeutics, Physical Optics Corporation (POC) proposes to develop a Multifunctional Antisense Therapeutics Nanocarrier and Inhalation Device (MATEN). This proposed system is based on a new dry powder formulation and a novel design of an inhaler that uses in-house developed mature compone ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  9. 3D Microfluidic Platform for in vitro Hematopoietic Stem Cell (HSC) Culture

    SBC: Physical Optics Corporation            Topic: CBD10103

    To address the Chemical/Bio Defense (CBD) need for in vitro models suitable for high-throughput screening of drug toxicities in human tissues, Physical Optics Corporation (POC) proposes to develop a new three-dimensional (3D) Microfluidic Platform for in-vitro Hematopoietic Stem Cell (HSC) Culture (3D-Mic-Stem). This proposed system is based on a 3D microfluidic design that uses HSCs for assaying ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  10. Microfluidic Dielectrophoretic Screening System

    SBC: Physical Optics Corporation            Topic: CBD10107

    To address the U.S. Army/DTRA’s CBD program need for a robust screening process for use with large panels of enzymes to identify variants with higher affinity for organophosphorus (OP) substrates, Physical Optics Corporation (POC) proposes to develop a Microfluidic Dielectrophoretic Screening (MDS) system. This proposed system is based on the new design of a microfluidic mixer, enzymatic reactor ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
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