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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Method for Discovering Novel Transcriptional Regulators

    SBC: CROSSLINK GENETICS CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Regulation of gene expression by transcription factors is one of the most fundamental biological processes. The pharmaceutical manipulation of this process would open doors toward new approaches to treatment of cancer and other major diseases. We aim to develop a novel, comprehensive technology for manipulation of gene expression based on synthetic analogu ...

    STTR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  2. METHOD FOR DISCOVERING NOVEL TRANSCRIPTIONAL REGULATORS

    SBC: CROSSLINK GENETICS CORPORATION            Topic: N/A

    N/A

    STTR Phase I 1998 Department of Health and Human Services
  3. Mapping disease-specific human protein networks

    SBC: Curagen Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): While the human genome sequence is known, medical advances will require knowledge of how individual genes and proteins assemble into functional biological networks. These networks are built in part through physical interactions between proteins. Protein interaction networks can now be probed using highthroughput experimental methods, yet challenges remain: dat ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  4. N/A

    SBC: Cutanogen, Inc.            Topic: N/A

    N/A

    STTR Phase I 2000 Department of Health and Human ServicesNational Institutes of Health
  5. N/A

    SBC: Cutanogen, Inc.            Topic: N/A

    N/A

    STTR Phase II 2000 Department of Health and Human ServicesNational Institutes of Health
  6. N/A

    SBC: Cynosure, Inc.            Topic: N/A

    N/A

    STTR Phase I 2000 Department of Health and Human ServicesNational Institutes of Health
  7. N/A

    SBC: Cynosure, Inc.            Topic: N/A

    N/A

    STTR Phase II 2000 Department of Health and Human ServicesNational Institutes of Health
  8. SCANNING CYTOMETRY FOR BONE MARROW PURGING

    SBC: CYNTELLECT, INC.            Topic: N/A

    N/A

    STTR Phase I 1999 Department of Health and Human Services
  9. Cellular Ion Control by Laser-Induced Permeabilization

    SBC: CYNTELLECT, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Cells have intricate control mechanisms for regulating intracellular concentrations of several key ions, and ion imbalances often lead to dramatic consequences on cell physiology. Therefore, many researchers study how various ions and their concentrations affect cells, and the impact of various pharmaceutical agents on these parameters. Current techniques for a ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  10. Cell-based screening of combinatorial siRNA libraries

    SBC: CYNTELLECT, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): RNA interference (RNAi) is a specific post-transcriptional gene silencing pathway mediated by intracellular dsRNAs of 21-23 bp in length known as small interfering RNA (siRNA). Since the recent discovery of effective siRNA-mediated gene silencing in mammalian cells, there has been significant validation and enormous interest in the approach from both academic a ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
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