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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 195981 - 195990 of 207712 results
  1. Microscope system for large scale optical imaging of neuronal activity using kilohertz frame rates

    SBC: MICROBRIGHTFIELD, LLC            Topic: 105

    Abstract This project aims to develop the 2P-ActivityScope™, a revolutionary new microscope based on a technological breakthrough called second-generation Scanned Line Angular Projection (SLAP2) two photon laser scanning microscopy that was recently developed by Dr. Kaspar Podgorski (Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA). The game-changing innovation in the 2P-Ac ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  2. Clinical study of a wearable therapeutic ultrasound sleeve for treatment of neuro-ischemic and ischemic diabetic foot ulcers

    SBC: Vibrato Medical, Inc.            Topic: 200

    PROJECT SUMMARY Diabetes mellitus (DM) is a common condition (34M in USA). Approximately 1 in 7 DM patients have diabetic foot ulcers (DFU). Approximately half of patients with DFU have concomitant peripheral arterial disease (PAD), resulting in US prevalence of 2.5M patients with ischemic or neuroischemic DFUs. Patients with DFUs experience recurrent hospitalizations, chronic wound healing issues ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  3. Inhalation Repurposing of An Approved Drug to Treat Severe Asthma

    SBC: AEON RESPIRE, INC.            Topic: NHLBI

    Project Summary The business objective of Aeon Respire, and the purpose of this SBIR Project, is to execute key steps towards repurposing niclosamide as a new asthma treatment. The therapeutic rationale for these studies is based on initial findings that niclosamide inhibits an ion channel that is pivotal for airway smooth muscle contraction and mucin hypersecretion. Both of these pathologic proce ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  4. Opioid-Sparing pain management for Chronic Low Back Pain patients using TMC-CP01- A VANISH (Virtual Autonomic Neuromodulation Induced Systemic Healing) based program

    SBC: TAMADE LLC            Topic: NIDA

    An estimated 100 million Americans suffer from chronic pain and low back pain is the leading type of chronic pain. In fact, low back pain (LBP) is the number one cause of disability in the world and in the U.S. this chronic disease accounts for 264 million lost work days in one year. While 31 million Americans suffer from chronic low back pain (CLBP), today the most commonly prescribed drug for lo ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  5. A New and Disruptive Gene Based Therapy for Atrial Fibrillation

    SBC: Inomagen Therapeutics, Inc            Topic: NHLBI

    PROJECT SUMMARY Atrial fibrillation (AF) is the most common heart rhythm disorder that affects rt3 million Americans and is a major cause of stroke. Since AF is primarily an age-related disease, it is fast becoming an epidemic in a rapidly aging population. Unfortunately, current therapeutic approaches to AF – both pharmacological and ablation- based - are sub-optimal in patients with persistent ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  6. Magnetic Rotational Exploratory Platform for Coronary Lesions

    SBC: UNANDUP, LLC            Topic: NHLBI

    Cardiovascular disease (CVD) is the leading cause of mortality in the United States (US), resulting in 850,000 annual deaths, of which nearly 400,000 are associated with coronary heart disease (CHD) and myocardial infarction (MI). By 2030, global annual deaths will exceed 20 million. More than 90 million US adults currently live with CVD, which is associated with an annual economic burden of more ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  7. SBIR Phase I:Oral delivery systems for sterilizing strains of a sexually-transmitted insect virus

    SBC: LEPIDEXT, INC.            Topic: BT

    The Broader Impact of this Small Business Innovation Research (SBIR) Phase I project is to support widespread distribution and adoption of sterilizing biopesticides that are effective and efficient to control Lepidoptera. Lepidopterans, such as the corn earworm, circumvent insecticidal properties of certain crops by developing resistance.Models show that incorporating sterile insects in a corn ear ...

    SBIR Phase I 2022 National Science Foundation
  8. SBIR Phase II:A STEM curriculum platform using augmented reality for real-time collaboration and problem solving

    SBC: EXPLORE INTERACTIVE, INC            Topic: LC

    The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project is to use augmented reality (AR) to activate rich and measurable STEM experiences such as engineering design projects for any child anywhere in the world. The market for AR globally and specifically in education is projected to reach over $200 B and $60 B respectively by 2025 by growing at 40 ...

    SBIR Phase II 2022 National Science Foundation
  9. Hearable System for Impact and Blast

    SBC: PAXAURIS LLC            Topic: DHA20B002

    Service members need head protection that goes beyond the impact protection provided by their helmets. Traumatic brain injury (TBI) can last years with severe consequences. Repeated mild traumatic brain injuries (mTBI) can affect performance and build to permanent damage. Monitoring impact and blast exposure will enable the military to protect service members’ health by evaluating the effectiven ...

    STTR Phase II 2022 Department of DefenseDefense Health Agency
  10. Crypto-Financial Mapping for Critical Infrastructure and Austere Environments

    SBC: INCA DIGITAL FEDERAL LLC            Topic: J201CSO1

    Complex systems like those in biology, ecology, and finance are ever evolving and difficult to represent. Emergent agents and properties can lead to rapid paradigm shifts within entire ecosystems. Changes and vulnerabilities that may seem small or are not apparent can emerge at the level of the system as a whole. Blockchain technology, and cryptocurrency more specifically, are evolving at a faster ...

    SBIR Phase II 2022 Department of DefenseDefense Advanced Research Projects Agency
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