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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 195981 - 195990 of 207714 results
  1. Analgesics Targeting TRPA1 for Treatment of Chronic Pain

    SBC: ALGOMEDIX, INC.            Topic: NIDA

    DESCRIPTION (provided by applicant): Title: Analgesics Targeting TRPA1 for Treatment of Chronic Pain Abstract An effective treatment for chronic pain that is devoid of both addictive potential and abuse liability is a major unmet need in medicine today. These limitations drive the need for novel treatment options based on new molecular mechanisms. Our goal is to identify and develop a novel, ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  2. Point-of-care Testing for Illicit Drugs and Alcohol Intoxication in an Emergency

    SBC: SEACOAST SCIENCE, INC.            Topic: NIDA

    DESCRIPTION (provided by applicant): This Small Business Innovation Research Phase I proposal focuses on the development of a high-speed chromatographic analysis system based on a chemical sensor array that is specialized for the detection of ethanol and narcotics. The core technology is a miniature gas chromatograph that will utilize a dual detector system based on a MEMS microcapacitor sensor ar ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  3. Nicotine delivery to rodents with lung alveolar region-targeted aerosol tech

    SBC: AFASCI, INC.            Topic: NIDA

    DESCRIPTION (provided by applicant): This application is in response to NIH/PSH 2010-2 'Omnibus solicitation for SBIR/STTR Grant Application' under NIDA 2, Development of Alternate Drug Delivery Dosage Forms for Drugs Abuse Studies . Through the use of tobacco, nicotine is one of the most heavily used addictive drugs and the leading preventable cause of disease, disability, and death in ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  4. Transdermal Cannabidiol Prodrug Delivery

    SBC: ALLTRANZ, INC.            Topic: NIDA

    DESCRIPTION (provided by applicant): With over 8.5% of the U.S. population and 75 million people worldwide meeting the diagnostic criteria for alcohol use disorders (AUDs), alcohol abuse is among the top three preventable public health problems in the U.S.and the world. AUDs, commonly referred to as alcoholism, have a complex etiology where chronic alcohol associated neurodegeneration, withdrawal- ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  5. Mu opioid agonists with reduced side effects for the treatment of pain

    SBC: MENCURO THERAPEUTICS, INC.            Topic: NIDA

    DESCRIPTION (provided by applicant): New approaches are needed to improve the treatment options of over 50 million people in the United States suffering from chronic pain. The proposed research is designed to develop a novel class of opioid analgesicsthat produce less tolerance and may potentially reduce opiate-associated side effects. Opioid ligands activate G protein coupled receptors (GPCR) ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  6. Multi-day Pain Management Therapy with Novel Injectable Formulation

    SBC: ORBIS BIOSCIENCES, INC.            Topic: NIDA

    DESCRIPTION (provided by applicant): Our long term goal is to widespread the use of PPF technology for promoting effective production of drug-encapsulating microparticles with uniform size and physical characteristics that can be leveraged to release a specific drug at controlled rates over multi-day periods in vivo after a single administration. For this proposal, we are specifically targeting a ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  7. ACES: A Product to Suppress or Enhance Critical Components in Acoustic Signals

    SBC: Speech Technology and Applied Research Corporation            Topic: NIDCD

    DESCRIPTION (provided by applicant): Common acoustic environments are often complex mixtures of sounds from multiple acoustic sources. Some of these sources contain critical information listeners need to comprehend; others are distractions that interfere with listeners6 comprehension. As the US population ages, a significant and growing segment have difficulty coping with such complex sound fi ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  8. Computerized System for Phonemic Awareness Intervention

    SBC: BIOSPEECH INC            Topic: NIDCD

    DESCRIPTION (provided by applicant): Phonemic awareness, defined as ... the ability to notice, think about, and work with the individual sounds in spoken words (National Institute for Literacy, 2000), is considered a necessary skill for literacy. The financial and quality-of-life costs of these impairments are significant, not only because of the link with reading difficulties and hence with fut ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  9. Improved Noise Attenuation Foam for In the Ear Hearing and Noise Devices

    SBC: HEARING COMPONENTS, INC.            Topic: NIDCD

    DESCRIPTION (provided by applicant): Viscoelastic foam earplugs are commonly used for personal hearing protection to help reduce the incidence of hearing loss; however, many work environments exist where the protection from currently available earplugsis insufficient. In addition, the ability of existing foam earplugs to attenuate low frequency energy is relatively poor. Pilot experiments were ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  10. Molded Hydrogel Tympanic Membrane Repair Constructs

    SBC: GRACE MEDICAL, INC.            Topic: NIDCD

    DESCRIPTION (provided by applicant): Tympanic membrane perforations are commonly seen in otology practices and about 150,000 repair surgeries are performed each year in the United States. Current office-based procedures such as paper patch tympanoplasty are relatively ineffective or, like the irritant oil method, require multiple office visits. Surgical procedures including fascia and cartilag ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
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