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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 196021 - 196030 of 207714 results
  1. Hydraulic Artificial Urinary Sphincter (HydrAUS)

    SBC: GT UROLOGICAL, LLC            Topic: NIDDK

    Hydraulic Artificial Urinary Sphincter - HydrAUS GT Urological, LLC. has prepared this NIH SBIR Phase I Grant Application entitled Hydraulic Artificial Urinary Sphincter - HydrAUS to detail goals and activities related to the design and development ofan implantable, hydraulic urinary sphincter intended to safely and effectively prevent urinary leakage in males and females suffering from Urin ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  2. Optimized Receptor Binding Profile in an Ultra-Stable, Ultra-Rapid-Acting Insulin

    SBC: THERMALIN DIABETES, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): We seek to develop an ultra-fast, zinc-free insulin analog formulation for the treatment of diabetes mellitus. An ultra-fast pharmacokinetic-dynamic (PK/PD) profile promises to enable superior performance of pump therapy (continuous subcutaneous insulin infusion) with enhanced safety and more robust integration with glucose- sensing technologies. Ultra-fast kin ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  3. Anti-CD47 mAb Therapy to Improve Kidney Transplantation

    SBC: VASCULOX, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Organ transplantation is one of the great success stories of modern medicine. However, the supply of suitable organs lags far behind the need and many patients die while waitlisted for organs. While there have been manyrecent strides in organ procurement, preservation and follow-up immune suppression, prevention of ischemia-reperfusion injury (IRI) remains prob ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  4. Online patient self-assessment for chronic pancreatic and other pain

    SBC: CPM SYSTEMS, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): The pain associated with chronic pancreatitis is challenging to treat and to investigate. Chronic pancreatic pain (CPP) reflects multiple potential mechanisms: visceral factors (e.g., obstruction, inflammation), neuropathic pain due to central sensitization, and psychosocial and behavioral factors (e.g., depression, anxiety disorders, trauma or abuse, poorly to ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  5. Concentrating anti-UTI phytochemicals from cranberry in a functional food matrix

    SBC: Nutrasorb LLC            Topic: NIDDK

    DESCRIPTION (provided by applicant): The overall goal of this Phase 1 SBIR proposal resubmission (revised according the recommendations of the review panel) is to demonstrate that the biologically-active phytochemicals naturally present in the American cranberry, in particular, the anti-infective A-type proanthocyanidins that are clearly linked to prevention of urinary tract infections (UTIs) in h ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  6. Development of a discovery platform based on microfluidics and fluorescent cell f

    SBC: NIVARTA, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): The overall goal of the project is to develop discovery platform based on microfluidics and functional cell assays that is suitable for screening hundreds of proteins or small-molecule compounds simultaneously in a cost-effective and high throughput manner. The projects Specific Aims are: (1) To develop a microfluidic-based platform for high-throughput screenin ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  7. Advanced Hypoglycemia Prevention Capabilities in Fuzzy Logic Artificial Pancreas

    SBC: DOSE SAFETY INC            Topic: NIDDK

    DESCRIPTION (provided by applicant): The ultimate technical objective of this research is the development of an Artificial Pancreas (AP) controller that improves metabolic control and decreases glycemic excursions by robustly preventing hypoglycemic episodes. Proportional-integral-derivative control (PID) and model predictive control (MPC) have been widely considered to be promising candidate for ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  8. Improving Host Response to Implantable Glucose Sensors via Nitric Oxide Release

    SBC: Novan, Inc.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Approximately 24 million adults and children in the United States have 1 Diabetes Mellitus (diabetes) and 1.6 million new cases are diagnosed each year. Type 2 is the most common form of the disease accounting for over90% of the diabetics worldwide. The remaining 5 to 10% of diabetics are plagued with the more serious Type 1 condition which is most often diagno ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  9. Long-term Luminescence-based Glucose Monitoring

    SBC: PROFUSA, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Currently available continuous glucose sensors are inaccurate and prone to failure, making the goal of an artificial pancreas elusive. Furthermore, their designs are not patient-friendly and they require frequent user input (e.g. calibration). The largest hurdle in developing implantable glucose sensors is the foreign body response (FBR). In this Phase I SBIR, ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  10. Improving the Kinetics and Reliability of Continuous Glucose Monitoring

    SBC: Theranova LLC            Topic: NIDDK

    DESCRIPTION (provided by applicant): Patients with type 1 diabetes mellitus (T1DM) will experience dramatic improvements in their quality of life and life expectancy when the goal of engineering an artificial pancreas is finally realized. A critical component of such a system is to be able to measure changes in blood glucose rapidly, accurately, and continuously. Implantable continuous glucose mo ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
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